Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shraddha, Gaonkar"'
Autor:
Tyler Landrith, Bing Li, Ashley A. Cass, Blair R. Conner, Holly LaDuca, Danielle B. McKenna, Kara N. Maxwell, Susan Domchek, Nichole A. Morman, Christopher Heinlen, Deborah Wham, Cathryn Koptiuch, Jennie Vagher, Ragene Rivera, Ann Bunnell, Gayle Patel, Jennifer L. Geurts, Morgan M. Depas, Shraddha Gaonkar, Sara Pirzadeh-Miller, Rebekah Krukenberg, Meredith Seidel, Robert Pilarski, Meagan Farmer, Khateriaa Pyrtel, Kara Milliron, John Lee, Elizabeth Hoodfar, Deepika Nathan, Amanda C. Ganzak, Sitao Wu, Huy Vuong, Dong Xu, Aarani Arulmoli, Melissa Parra, Lily Hoang, Bhuvan Molparia, Michele Fennessy, Susanne Fox, Sinead Charpentier, Julia Burdette, Tina Pesaran, Jessica Profato, Brandon Smith, Ginger Haynes, Emily Dalton, Joy Rae-Radecki Crandall, Ruth Baxter, Hsiao-Mei Lu, Brigette Tippin-Davis, Aaron Elliott, Elizabeth Chao, Rachid Karam
Publikováno v:
npj Precision Oncology, Vol 4, Iss 1, Pp 1-9 (2020)
Abstract Germline variants in tumor suppressor genes (TSGs) can result in RNA mis-splicing and predisposition to cancer. However, identification of variants that impact splicing remains a challenge, contributing to a substantial proportion of patient
Externí odkaz:
https://doaj.org/article/50f2e0c212b24359a87e5f0fd59980ac
Autor:
Gayle Patel, Morgan M Depas, Lily Hoang, Rob Pilarski, Brigette Tippin Davis, Elizabeth Hoodfar, Cara S. Dresbold, Olivia L. Tan, Meagan Farmer, Danielle Menashe, Samantha Stachowiak, Deborah Wham, Khateriaa Pyrtel, Sandra B. Jenkinson, Tiffani Demarco, Sara Pirzadeh-Miller, Elizabeth C. Chao, Danielle McKenna, Catherine Koptiuch, Jessica Profato, Rebekah C. Krukenberg, Jennifer L. Geurts, John G. Lee, Shraddha Gaonkar, Jen Moore, Nichole A. Morman, Danielle Dondanville, Deepika Nathan, Rachid Karam, Meredith Seidel, Holly LaDuca, Amal Yussuf, Kara J. Milliron, Carolyn Horton, Jill S. Dolinsky, Diane Samad, Cassie Garcia
Publikováno v:
Cancer Research. 80:P6-08
BACKGROUND: Germline genetic testing is routinely incorporated into clinical care for breast cancer patients to inform management decisions and reduce risk for developing subsequent cancers. While the diagnostic yield of cancer genetic testing has in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a50932ad25e8a5992a3fd2a38eb880ba
https://doi.org/10.1158/1538-7445.sabcs19-p6-08-08
https://doi.org/10.1158/1538-7445.sabcs19-p6-08-08
Autor:
Whitney, Espinel, Marjan, Champine, Heather, Hampel, Joanne, Jeter, Kevin, Sweet, Robert, Pilarski, Rachel, Pearlman, Kate, Shane, Pamela, Brock, Judith A, Westman, Lindsay, Kipnis, Jilliane, Sotelo, Anu, Chittenden, Samantha, Culver, Jill E, Stopfer, Katherine A, Schneider, Rosalba, Sacca, Diane R, Koeller, Shraddha, Gaonkar, Erica, Vaccari, Sarah, Kane, Scott T, Michalski, Shan, Yang, Sarah M, Nielsen, Sara L, Bristow, Stephen E, Lincoln, Robert L, Nussbaum, Edward D, Esplin
Publikováno v:
Cancers. 14(10)
Consensus guidelines for hereditary breast and ovarian cancer include management recommendations for pathogenic/likely pathogenic (P/LP) variants in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24cf0bd64bd4582859098cbce772d872
https://pubmed.ncbi.nlm.nih.gov/35626031
https://pubmed.ncbi.nlm.nih.gov/35626031
Autor:
Lauren K. Brais, Shraddha Gaonkar, Brian M. Wolpin, Chinedu Ukaegbu, Hajime Uno, Sapna Syngal, Kimberly Perez, Matthew B. Yurgelun, Meghan Underhill-Blazey, Anu Chittenden, Sigurdis Haraldsdottir
Publikováno v:
JCO Oncol Pract
PURPOSE: National guidelines recommend genetic counseling and multigene germline testing (GC/MGT) for all patients with pancreatic ductal adenocarcinoma (PDAC). This study's aim was to assess real-world effectiveness of implementing systematic GC/MGT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba345adbcf697c5f7ad5726503247ad2
https://europepmc.org/articles/PMC8257923/
https://europepmc.org/articles/PMC8257923/
Autor:
Meagan Farmer, Brandon Smith, Kara N. Maxwell, Brigette Tippin-Davis, Julia Burdette, Danielle McKenna, Ashley A. Cass, Sinead Charpentier, Sitao Wu, Emily Dalton, Melissa Parra, Susanne Fox, Aaron Elliott, Holly LaDuca, Cathryn Koptiuch, Susan M. Domchek, Elizabeth Hoodfar, Robert Pilarski, Dong Xu, Khateriaa Pyrtel, Kara J. Milliron, Michele Fennessy, Gayle Patel, Lily Hoang, Morgan M Depas, Tina Pesaran, Rachid Karam, Meredith Seidel, Ann Bunnell, Huy Gia Vuong, Deborah Wham, Bing Li, Ragene Rivera, Jennie Vagher, Nichole A. Morman, Aarani Arulmoli, Sara Pirzadeh-Miller, Hsiao-Mei Lu, Jessica Profato, Joy Rae-Radecki Crandall, Elizabeth C. Chao, Ruth Baxter, Shraddha Gaonkar, Ginger Haynes, Amanda Ganzak, Deepika Nathan, Jennifer L. Geurts, Blair R. Conner, Tyler Landrith, Rebekah Krukenberg, John J. Lee, Christopher Heinlen, Bhuvan Molparia
Publikováno v:
npj Precision Oncology, Vol 4, Iss 1, Pp 1-9 (2020)
NPJ Precision Oncology
NPJ Precision Oncology
Germline variants in tumor suppressor genes (TSGs) can result in RNA mis-splicing and predisposition to cancer. However, identification of variants that impact splicing remains a challenge, contributing to a substantial proportion of patients with su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d16807d808110f22b027a699b83d981
https://doi.org/10.1038/s41698-020-0109-y
https://doi.org/10.1038/s41698-020-0109-y
Autor:
Kimberly Perez, Matthew B. Yurgelun, Audrey P. Madigan, Andrew J. Aguirre, Anu Chittenden, Chinedu Ukaegbu, Sapna Syngal, Shraddha Gaonkar, Brian M. Wolpin, James M. Cleary
Publikováno v:
Journal of Clinical Oncology. 38:678-678
678 Background: MGT identifies cancer susceptibility gene variants in 4-10% of unselected PC pts. Such data have prompted national guidelines to recommend GC and MGT of all PC pts, but the benefits and barriers to implementing systematic testing are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd82271cdfeb9dbbe346429c727c4c4a
https://doi.org/10.1200/jco.2020.38.4_suppl.678
https://doi.org/10.1200/jco.2020.38.4_suppl.678
Autor:
Thomas A. Abrams, Shraddha Gaonkar, Thomas E. Clancy, Tara G. Dhingra, Chinedu Ukaegbu, Lauren K. Brais, Anu Chittenden, James M. Cleary, Jiliane Sotelo, Audrey P. Madigan, Kimberly Perez, Matthew B. Yurgelun, Nadine Jackson McCleary, Brian M. Wolpin, Sapna Syngal, Douglas A. Rubinson
Publikováno v:
Journal of Clinical Oncology. 36:1512-1512
1512Background: MGT will identify cancer susceptibility gene variants in 4-10% of unselected PC pts. Such data have prompted calls for universal GC and MGT of all PC pts, but the real-world benefit...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5938059644814845b6c776fdd0ae6e03
https://doi.org/10.1200/jco.2018.36.15_suppl.1512
https://doi.org/10.1200/jco.2018.36.15_suppl.1512
Autor:
Rachel Pearlman, Heather Hampel, Rosalba Sacca, Robert Pilarski, Katherine A. Schneider, Pamela Brock, Edward D. Esplin, Whitney Espinel, Diane R. Koeller, Kevin Sweet, Lindsay Kipnis, Anu Chittenden, Joanne M. Jeter, Marjan Champine, Jill Stopfer, Shraddha Gaonkar, Jilliane Sotelo, Kate P Shane-Carson, Judith A. Westman, Samantha Stickevers
Publikováno v:
Journal of Clinical Oncology. 36:e18705-e18705
e18705Background: Germline testing guidelines are centered on BRCA1 and BRCA2 despite clear medical management recommendations in several other high and moderate penetrance genes. Clinician utiliza...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f63dfee931a10ef82c1fbe719bd8d505
https://doi.org/10.1200/jco.2018.36.15_suppl.e18705
https://doi.org/10.1200/jco.2018.36.15_suppl.e18705
Autor:
Robert L. Nussbaum, S Stickevers, S Cochrane, K Shane, L Kipnis, P Brock, D Koeller, Shan Yang, J Sotelo, J Jeter, K Sweet, R Sacca, Edward D. Esplin, Stephen E Lincoln, Robert Pilarski, A Chittenden, M Champine, Scott T. Michalski, K Schneider, Judith A. Westman, E Vaccari, W Espinel, Heather Hampel, R Pearlman, Jill E. Stopfer, Shraddha Gaonkar
Publikováno v:
Cancer Research. 78:P3-03
Background The clinical utility of germline genetic testing for BRCA1 and BRCA2 has long been established. However, management recommendations for pathogenic variants in other genes, typically included in multigene panels, have only recently been inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d97cd06ebd1da994aaf870d55a7f260
https://doi.org/10.1158/1538-7445.sabcs17-p3-03-01
https://doi.org/10.1158/1538-7445.sabcs17-p3-03-01
Autor:
Espinel, Whitney1 (AUTHOR) whitney.espinel@hci.utah.edu, Champine, Marjan1 (AUTHOR) mjchampine@gmail.com, Hampel, Heather2 (AUTHOR) hhampel@coh.org, Jeter, Joanne2 (AUTHOR) joanne.jeter@hci.utah.edu, Sweet, Kevin2 (AUTHOR) kevin.sweet@osumc.edu, Pilarski, Robert2 (AUTHOR) rpilarski@ambrygen.com, Pearlman, Rachel2 (AUTHOR) rachel.pearlman@osumc.edu, Shane, Kate2 (AUTHOR) kate.shane@osumc.edu, Brock, Pamela2 (AUTHOR) pamela.brock@osumc.edu, Westman, Judith A.2 (AUTHOR) judith.westman@osumc.edu, Kipnis, Lindsay3 (AUTHOR) lindsay_kipnis@dfci.harvard.edu, Sotelo, Jilliane3 (AUTHOR) jilliane.sotelo@thermofisher.com, Chittenden, Anu3 (AUTHOR) anu_chittenden@dfci.harvard.edu, Culver, Samantha3 (AUTHOR) samantha.culver@invitae.com, Stopfer, Jill E.3 (AUTHOR) jille_stopfer@dfci.harvard.edu, Schneider, Katherine A.3 (AUTHOR) katherine_schneider@dfci.harvard.edu, Sacca, Rosalba3 (AUTHOR) saccar@mskcc.org, Koeller, Diane R.3 (AUTHOR) dianer_koeller@dfci.harvard.edu, Gaonkar, Shraddha3 (AUTHOR) shraddha.gaonkar@invitae.com, Vaccari, Erica3 (AUTHOR) erica.m.vaccari@gmail.com
Publikováno v:
Cancers. May2022, Vol. 14 Issue 10, p2426-N.PAG. 13p.