Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Shozo Takayama"'
Publikováno v:
Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
This review covers chemical carcinogenesis studies in nonhuman primates performed by the National Cancer Institute, USA, to provide hitherto unavailable information on their susceptibility to compounds producing carcinogenic effects in rodents. From
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a00da6822e26758e76a5d2b5cf4a3d
https://doi.org/10.2183/pjab.84.176
https://doi.org/10.2183/pjab.84.176
Publikováno v:
Journal of Veterinary Epidemiology. 6:19-23
平成13年4月, A農場 (酪農, 飼養頭数: 220頭; 長野県) で, 流産した牛1頭にネオスポラ抗体が確認されたため, 浸潤状況と損失を分析し, 対策を検討した。その結果, 搾乳牛130頭を調査し, 陽性
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::568c3bcc83883502c5a52cc61d711177
https://doi.org/10.2743/jve.6.19
https://doi.org/10.2743/jve.6.19
Autor:
S. L. Johansson, M. Tsutsumi, Unnur P. Thorgeirsson, A. G. Renwick, Dalgard Dw, Shozo Takayama, S. M. Sieber
Publikováno v:
Toxicological Sciences. 53:33-39
Twenty-one monkeys (cynomolgus, rhesus, African green) were fed cyclamate (100 mg/kg and 500 mg/kg) in the diet five times per week from a few days after birth and continuing for up to 24 years. Malignant tumors were diagnosed in three 24-year-old cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d817dacc03f5f8c050e0d2ca0d7ff3
https://doi.org/10.1093/toxsci/53.1.33
https://doi.org/10.1093/toxsci/53.1.33
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 125:219-225
Because of reports on tumorigenic activity in different animal species exposed to DDT a decision was made in 1969 to evaluate the long-term effects of DDT on 24 cynomolgus and rhesus monkeys. DDT (20 mg/kg) was given in the diet for 130 months, follo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02126273c8dfc129cb580553917ad43
https://doi.org/10.1007/s004320050266
https://doi.org/10.1007/s004320050266
Autor:
Susan M. Sieber, Unnur P. Thorgeirsson, Samuel M. Cohen, Steven H. Eklund, Dan W. Dalgard, Richard H. Adamson, Lora L. Arnold, Shozo Takayama, M. Cano
Publikováno v:
JNCI: Journal of the National Cancer Institute. 90:19-25
Background: It was observed in the early 1970s that saccharin produced bladder cancer in rats. However, it has been unclear whether sodium saccharin when consumed by humans poses a substantial carcinogenic hazard. Numerous epidemiologic studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d7bd5bc2e17e4796acece8d61199489
https://doi.org/10.1093/jnci/90.1.19
https://doi.org/10.1093/jnci/90.1.19
Publikováno v:
Carcinogenesis. 1(2)
The binding of benzo(a)pyrene (BP) to DNA in the presence of liver microsomal preparations from 3-methylcholanthrene-treated rats was increased 28.5% (P < 0.001) by addition of UDP-glucuronic acid to the incubation mixture at a 100 microM concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e444563c0d02ea76bb80196de0c54b
https://pubmed.ncbi.nlm.nih.gov/22282989
https://pubmed.ncbi.nlm.nih.gov/22282989
Autor:
Amit Ghoshal, Elizabeth G. Snyderwine, Karl-Heinz Preisegger, Snorri S. Thorgeirsson, Shozo Takayama
Publikováno v:
Carcinogenesis. 15:2429-2433
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), a carcinogen found in cooked meat, was determined to be a mammary carcinogen in female Sprague-Dawley rats on a high fat diet. Forty-three-day-old female Sprague-Dawley rats received 10 doses of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860b75778f7213edd8a75efef33caf2b
https://doi.org/10.1093/carcin/15.11.2429
https://doi.org/10.1093/carcin/15.11.2429
Publikováno v:
Mutation Research/Genetic Toxicology. 259:399-410
Mutagenic heterocyclic amines in cooked foods were carcinogenic to mice, rats and/or monkeys, when they were given orally continuously. The most common target organ was the liver, but in CDF1 mice lung tumors, forestomach tumors, lymphomas/leukemias,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27d38629ddd04a28dce4074583b7b11
https://doi.org/10.1016/0165-1218(91)90130-e
https://doi.org/10.1016/0165-1218(91)90130-e
Autor:
Hiroko Ohgaki, Takashi Sugimura, Shozo Takayama, Zoltan Szentirmay, Keiichi Maruyama, Hiroyasu Esumi
Publikováno v:
Japanese Journal of Cancer Research : Gann
A signet ring cell carcinoma in the gastric antrum of a Cynomolgus monkey induced by N‐ethyl‐N′‐nitro‐N‐nitrosoguanidine was sequentially studied by endoscopy, biopsy, and autopsy. The carcinoma was first detected on the angulus of the st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40fcf8e161e001beb7a8b789291cdf4
http://europepmc.org/articles/PMC5917948
http://europepmc.org/articles/PMC5917948
Autor:
Dan W. Dalgard, Richard H. Adamson, Unnur P. Thorgeirsson, Snorri S. Thorgeirsson, Elizabeth G. Snyderwine, Takashi Sugimura, Shozo Takayama, Jeanette Reeves
Publikováno v:
Japanese Journal of Cancer Research : Gann
The carcinogenic potential of 2‐amino‐3‐methylimidazo[4,5f]quinoline (IQ) was evaluated in cynomolgus monkeys. Monkeys received IQ, beginning at the age of one year, at doses of 10 or 20 mg/kg by gavage. Thus far, IQ has induced hepatocellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cab463fb89dde006e7d4ee6fddaaae0
https://doi.org/10.1111/j.1349-7006.1990.tb02500.x
https://doi.org/10.1111/j.1349-7006.1990.tb02500.x