Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Shozo Nishida"'
Autor:
Masanobu Tsubaki, Tomoya Takeda, Takuya Matsuda, Kana Kishimoto, Honoka Takefuji, Yuzuki Taniwaki, Misa Ueda, Tadafumi Hoshida, Kazufumi Tanabe, Shozo Nishida
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background KRAS mutations are fraught with the progression of colorectal cancer and resistance to chemotherapy. There are pathways such as extracellular regulated protein kinase 1/2 (ERK1/2) and Akt downstream and farnesylation and geranylge
Externí odkaz:
https://doaj.org/article/574e7e3b1f0a4c66a81feedc7a68e2eb
Autor:
Mitsuki Tabata, Masanobu Tsubaki, Tomoya Takeda, Keisuke Tateishi, Katsumasa Tsurushima, Motohiro Imano, Takao Satou, Toshihiko Ishizaka, Shozo Nishida
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Current chemotherapies for Burkitt lymphoma (BL) have dramatically improved its clinical outcome. However, chemoresistance can lead to chemotherapy failure and very poor prognosis; thus, novel strategies are urgently required for
Externí odkaz:
https://doaj.org/article/71679fa4f83842319f69d72308f53430
Autor:
Masashi Yanae, Shinichiro Fujimoto, Kaori Tane, Maki Tanioka, Kimiko Fujiwara, Masanobu Tsubaki, Yuzuru Yamazoe, Yoshiyuki Morishima, Yasutaka Chiba, Shintaro Takao, Yoshifumi Komoike, Junji Tsurutani, Kazuhiko Nakagawa, Shozo Nishida
Publikováno v:
Journal of Bone Oncology, Vol 8, Iss C, Pp 18-22 (2017)
Background: Bone represents one of the most common sites to which breast cancer cells metastasize. Patients experience skeletal related adverse events (pathological fractures, spinal cord compressions, and irradiation for deteriorated pain on bone) e
Externí odkaz:
https://doaj.org/article/37c64dea0fb64444ae3ca308ef4db150
Autor:
Masanobu Tsubaki, Tomoya Takeda, Takuya Matsuda, Shiori Seki, Yoshika Tomonari, Shoutaro Koizumi, Miki Nagatakiya, Mai Katsuyama, Yuuta Yamamoto, Katsumasa Tsurushima, Toshihiko Ishizaka, Shozo Nishida
Publikováno v:
Biomedicines, Vol 9, Iss 1, p 33 (2021)
Multiple myeloma (MM) is an incurable malignancy often associated with primary and acquired resistance to therapeutic agents, such as proteasome inhibitors. However, the mechanisms underlying the proteasome inhibitor resistance are poorly understood.
Externí odkaz:
https://doaj.org/article/4fcafab1c8fc424aab4ffc18a3730b78
Autor:
Masanobu Tsubaki, Shuuji Genno, Tomoya Takeda, Takuya Matsuda, Naoto Kimura, Yuuma Yamashita, Yuusuke Morii, Kazunori Shimomura, Shozo Nishida
Publikováno v:
Biomedicines, Vol 9, Iss 1, p 35 (2021)
The high mortality rate of cancer is strongly correlated with the development of distant metastases at secondary sites. Although Rho GTPases, such as RhoA, RhoB, RhoC, and RhoE, promote tumor metastasis, the main roles of Rho GTPases remain unidentif
Externí odkaz:
https://doaj.org/article/e06148d08e254f55bb0e0ca9fe19010a
Autor:
Natsuki Kato, Keisuke Tateishi, Masanobu Tsubaki, Tomoya Takeda, Mikihiro Matsumoto, Katsumasa Tsurushima, Toshihiko Ishizaka, Shozo Nishida
Publikováno v:
Pharmaceuticals, Vol 14, Iss 1, p 30 (2020)
Chemotherapy-induced peripheral neuropathy is a common factor in limiting therapy which can result in therapy cessation or dose reduction. Gabapentin, a calcium channel inhibitor, and duloxetine, a serotonin noradrenaline reuptake inhibitor, are used
Externí odkaz:
https://doaj.org/article/5cbaddc26da642438f852a34f019915c
Autor:
Masanobu Tsubaki, Tomoya Takeda, Mikihiro Matsumoto, Natsuki Kato, Shota Yasuhara, Yu-ichi Koumoto, Motohiro Imano, Takao Satou, Shozo Nishida
Publikováno v:
Tumor Biology, Vol 40 (2018)
Chemotherapy-induced neuropathy is a highly problematic, dose-limiting effect of potentially curative regimens of cancer chemotherapy. When neuropathic pain is severe, patients often either switch to less-effective chemotherapy agents or choose to di
Externí odkaz:
https://doaj.org/article/df1c254299f3463c837e2b6cf8bdb1ec
Autor:
Daichiro Fujiwara, Masanobu Tsubaki, Tomoya Takeda, Yoshika Tomonari, Yu-ichi Koumoto, Katsuhiko Sakaguchi, Shozo Nishida
Publikováno v:
Tumor Biology, Vol 39 (2017)
Recently, statins have been demonstrated to improve cancer-related mortality or prognosis in patients of various cancers. However, the details of the apoptosis-inducing mechanisms remain unknown. This study showed that the induction of apoptosis by s
Externí odkaz:
https://doaj.org/article/f4f1ae15430d4521920701336ad49c88
Autor:
Yasuhiro Kidera, Hisato Kawakami, Tsutomu Sakiyama, Kunio Okamoto, Kaoru Tanaka, Masayuki Takeda, Hiroyasu Kaneda, Shin-ichi Nishina, Junji Tsurutani, Kimiko Fujiwara, Morihiro Nomura, Yuzuru Yamazoe, Yasutaka Chiba, Shozo Nishida, Takao Tamura, Kazuhiko Nakagawa
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101902 (2014)
Nephrotoxicity remains a problem for patients who receive cisplatin chemotherapy. We retrospectively evaluated potential risk factors for cisplatin-induced nephrotoxicity as well as the potential impact of intravenous magnesium supplementation on suc
Externí odkaz:
https://doaj.org/article/2127ad550f014310826f2ead74b7747e
Autor:
Masanobu Tsubaki, Tomoya Takeda, Takuya Matsuda, Akihiro Kimura, Remi Tanaka, Sakiko Nagayoshi, Tadafumi Hoshida, Kazufumi Tanabe, Shozo Nishida
Publikováno v:
BMB Reports. 56:78-83