Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Shozo Ajimi"'
Autor:
Naoki Hashizume, Yutaka Oshima, Makoto Nakai, Toshio Kobayashi, Takeshi Sasaki, Kenji Kawaguchi, Kazumasa Honda, Masashi Gamo, Kazuhiro Yamamoto, Yasuhiro Tsubokura, Shozo Ajimi, Yoshiyuki Inoue, Nobuya Imatanaka
Publikováno v:
Toxicology Reports, Vol 3, Iss , Pp 490-500 (2016)
A potentially useful means of predicting the pulmonary risk posed by new forms of nano-structured titanium dioxide (nano-TiO2) is to use the associations between the physicochemical properties and pulmonary toxicity of characterized forms of TiO2. In
Externí odkaz:
https://doaj.org/article/24bb576486c149ad87ccb34a08654c5d
Autor:
Toshio Kobayashi, Yasuhiro Tsubokura, Yutaka Oshima, Takeshi Sasaki, Kenji Kawaguchi, Kenji Koga, Kunio Uchida, Naohide Shinohara, Shozo Ajimi, Takakazu Kayashima, Makoto Nakai, Nobuya Imatanaka
Publikováno v:
Journal of Applied Toxicology. 43:649-661
Crystalline silica is an important cause of serious pulmonary diseases, and its toxic potential is known to be associated with its surface electrical properties. However, in vivo data clarifying the relevance of silica's toxic potential, especially i
Autor:
Yasuhiro Tsubokura, Yutaka Oshima, Takeshi Sasaki, Shozo Ajimi, Toshio Kobayashi, Nobuya Imatanaka, Makoto Nakai, Takako Muroi, Kenji Kawaguchi, Naohide Shinohara
Publikováno v:
Journal of Toxicologic Pathology
Occupational exposure to nickel oxide (NiO) is an important cause of respiratory tract cancer. Toxicity is known to be associated with the dissociated component, i.e. nickel (II) ions. To address the relationship between physicochemical properties, i
Autor:
Shozo Ajimi, Kenji Koga, Takakazu Kayashima, Sasaki Takeshi, Toshio Kobayashi, Yutaka Oshima, Yasuhiro Tsubokura, Kenji Kawaguchi, Makoto Nakai, Naohide Shinohara, Kunio Uchida, Nobuya Imatanaka
Background: Crystalline silica is an important cause of serious pulmonary diseases. The relationship between this hazard and various physicochemical parameters of crystalline silica has been studied for more than a century, and the toxic potential of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea1b85b98b3851a9f8e8d37744590194
https://doi.org/10.21203/rs.3.rs-51340/v1
https://doi.org/10.21203/rs.3.rs-51340/v1
Autor:
Naoki Hashizume, Shozo Ajimi, Nobuya Imatanaka, Yasuhiro Tsubokura, Takakazu Kayashima, Takeshi Sasaki, Kenji Kawaguchi, Makoto Nakai, Toshio Kobayashi, Yutaka Oshima
Publikováno v:
Regulatory Toxicology and Pharmacology. 81:233-241
The intratracheal (IT) test is useful for screening the pulmonary toxicity of inhaled materials, including nanomaterials. However, a standard procedure has not yet been authorized internationally, and the effects of different test parameters are unkn
Autor:
Toshio Kobayashi, Masashi Gamo, Naoki Hashizume, Makoto Nakai, Takeshi Sasaki, Yutaka Oshima, Nobuya Imatanaka, Shozo Ajimi, Yoshiyuki Inoue, Kenji Kawaguchi, Yasuhiro Tsubokura, Kazumasa Honda, Kazuhiro Yamamoto
Publikováno v:
Scipedia Open Access
Scipedia SL
Toxicology Reports, Vol 3, Iss, Pp 490-500 (2016)
Toxicology Reports
Scipedia SL
Toxicology Reports, Vol 3, Iss, Pp 490-500 (2016)
Toxicology Reports
A potentially useful means of predicting the pulmonary risk posed by new forms of nano-structured titanium dioxide (nano-TiO2) is to use the associations between the physicochemical properties and pulmonary toxicity of characterized forms of TiO2. In
Autor:
Yasuhiro Tsubokura, Ryuichi Hasegawa, Shozo Ajimi, Naoki Hashizume, Takayuki Koga, Sunao Aso, Takako Muroi, Yutaka Oshima, Katsumi Miyata, Toshio Kobayashi, Kotaro Furukawa, Yoshiyuki Inoue, Yuji Kusune, Satsuki Hoshuyama
Publikováno v:
Drug and chemical toxicology. 41(4)
We have conducted animal toxicity tests of chemicals for a chemical safety program implemented by the Ministry of Economy, Trade and Industry of Japan. Here we conducted a combined repeated-dose and reproductive/developmental toxicity screening test
Autor:
Takako Muroi, Kotaro Furukawa, Saori Takakura, Katsumi Miyata, Yuji Kusune, Satsuki Hoshuyama, Sunao Aso, Shozo Ajimi
Publikováno v:
Drug and Chemical Toxicology. 37:17-24
Ethyl tertiary-butyl ether (ETBE) is commonly used as an oxygenated gasoline additive. In this study, we evaluated its developmental toxicity in rats. ETBE was administered by gavage to 21 or 22 pregnant female Sprague-Dawley rats per group at dose l
Autor:
Naoki Hashizume, Yutaka Oshima, Toshio Kobayashi, Makoto Nakai, Shozo Ajimi, Yasuhiro Tsubokura, Nobuya Imatanaka
Publikováno v:
The Journal of toxicological sciences. 41(5)
Bronchoalveolar lavage fluid (BALF) is commonly examined for pulmonary toxicity in animal studies. Two common means of anesthesia before euthanasia and bronchoalveolar lavage in rats are intraperitoneal injection of pentobarbital and inhalation of is
Autor:
Toshio, Kobayashi, Yutaka, Oshima, Yasuhiro, Tsubokura, Naoki, Hashizume, Shozo, Ajimi, Takakazu, Kayashima, Makoto, Nakai, Takeshi, Sasaki, Kenji, Kawaguchi, Nobuya, Imatanaka
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 81
The intratracheal (IT) test is useful for screening the pulmonary toxicity of inhaled materials, including nanomaterials. However, a standard procedure has not yet been authorized internationally, and the effects of different test parameters are unkn