Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Shouzou Wei"'
Autor:
Megan M Shuey, Frederic T Billings, Shouzou Wei, Ginger L Milne, Hui Nian, Chang Yu, Nancy J Brown
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0175292 (2017)
Twenty to thirty percent of patients undergoing cardiac surgery develop acute kidney injury (AKI). In mice, inhibition of soluble epoxide hydrolase (sEH) attenuates renal injury following ischemia-reperfusion. We tested the hypothesis that functional
Externí odkaz:
https://doaj.org/article/89f5e6d017f94ee787bf194b3ec3094c
Autor:
Pavel Soucek, Shouzou Wei, F. P. Guengerich, Renata Kozevnikovova, Yune-Fang Ueng, David Vrána
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM). 56:e78-e81
Introduction Oxygenated metabolites of cholesterol (“oxysterols”) can influence carcinogenesis and contribute to resistance to endocrine therapy, an effect mostly described in vitro. Objectives We sought to establish a method for screening plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc4ad7abebbcead3c967883742b0d5c
https://doi.org/10.1515/cclm-2017-0409
https://doi.org/10.1515/cclm-2017-0409
Autor:
Alzbeta Kloudova-Spalenkova, F. Peter Guengerich, Shouzou Wei, Pavel Soucek, Yune-Fang Ueng, Katerina Kopeckova
Publikováno v:
J Steroid Biochem Mol Biol
Oxygenated metabolites of cholesterol (oxysterols) have been previously demonstrated to contribute to progression of various cancers and to modulate resistance to breast cancer endocrine therapy in vitro. We measured prognostic roles of circulating l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3edb4aade3887600cffbb1eb9aa46dd
https://pubmed.ncbi.nlm.nih.gov/31874216
https://pubmed.ncbi.nlm.nih.gov/31874216
Autor:
F. Peter Guengerich, John R. Falck, Mei Hui Hsu, Jorge H. Capdevila, Üzen Savas, Shouzou Wei, Eric F. Johnson
Publikováno v:
Journal of Biological Chemistry. 291:16904-16919
Male and female homozygous 129/Sv mice carrying four copies of the human cytochrome P450 4A11 gene (CYP4A11) under control of its native promoter (B-129/Sv-4A11(+/+)) develop hypertension (142 ± 8 versus 113 ± 7 mm Hg systolic blood pressure (BP)),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57dc5e2fcffc190446321cc3dd2c031d
https://doi.org/10.1074/jbc.m116.732297
https://doi.org/10.1074/jbc.m116.732297
Autor:
Ginger L. Milne, Hui Nian, Megan M Shuey, Frederic T. Billings, Chang Yu, Shouzou Wei, Nancy J. Brown
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 5, p e0175292 (2017)
PLoS ONE, Vol 12, Iss 5, p e0175292 (2017)
Twenty to thirty percent of patients undergoing cardiac surgery develop acute kidney injury (AKI). In mice, inhibition of soluble epoxide hydrolase (sEH) attenuates renal injury following ischemia-reperfusion. We tested the hypothesis that functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3223974b31c32c4ea6aa1fe4eddad93b
http://europepmc.org/articles/PMC5446112
http://europepmc.org/articles/PMC5446112
Autor:
Satish Srinivasan, Leslie D. Nagy, Narayan G. Avadhani, Jyotirmoy Ghosh, F. Peter Guengerich, Prachi Bajpai, Shouzou Wei
Publikováno v:
The Journal of biological chemistry. 289(43)
In this study, we found that the full-length CYP2C8 (WT CYP2C8) and N-terminal truncated splice variant 3 (∼ 44-kDa mass) are localized in mitochondria in addition to the endoplasmic reticulum. Analysis of human livers showed that the mitochondrial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750c42042e80ac9a3a0db8b6edb199b0
https://pubmed.ncbi.nlm.nih.gov/25160618
https://pubmed.ncbi.nlm.nih.gov/25160618
Publikováno v:
The FASEB Journal. 28
Cytochrome P450 (P450) 2U1 has been shown to be expressed (at the mRNA level) in human brain and thymus. In order to elucidate the physiological function of this enzyme, an LC-MS-based metabolomics...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1c3fe053f648bab7b1c26669854ffca
https://doi.org/10.1096/fasebj.28.1_supplement.lb174
https://doi.org/10.1096/fasebj.28.1_supplement.lb174
Autor:
Shouzou Wei, Bruce D. Hammock, J. H. Capdevila, J. R. Snapper, Darryl C. Zeldin, John R. Falck
Publikováno v:
Archives of Biochemistry and Biophysics. 316:443-451
The metabolism of cis-epoxyeicosatrienoic acids (EETs), methyl cis-epoxyeicosatrienoates, and cis-epoxyeicosanoic acids by cytosolic epoxide hydrolase was studied to identify substrate structural features important for stereoselective metabolism and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f01df3f26edabe66362524b680753e
https://doi.org/10.1006/abbi.1995.1059
https://doi.org/10.1006/abbi.1995.1059
Autor:
Siddam Anjaiah, Vijaya L. Manthati, Jorge H. Capdevila, John D. Imig, Venugopal Raju Tuniki, Shouzou Wei, Bhavani Sangras, Ahmed A. Elmarakby, John R. Falck, Kasem Nithipatikom, D. Sudarshan Reddy
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 1 (2010)
Frontiers in Physiology, Vol 1 (2010)
Epoxyeicosatrienoic acids (EETs) contribute importantly to the regulation of vascular tone and blood pressure control. The purpose of this study was to develop stable EET analogs and test their in vivo blood pressure lowering effects in hypertensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440c90eed0d1cce61d22961d74306951
https://doi.org/10.3389/fphys.2010.00157
https://doi.org/10.3389/fphys.2010.00157
Autor:
F. P. Guengerich, H. R. Jacobson, Jorge H. Capdevila, J Yan, Raymond N. DuBois, John R. Falck, Shouzou Wei, Armando Karara
Publikováno v:
Scopus-Elsevier
The rat kidney microsomal epoxygenase catalyzed the asymmetric epoxidation of arachidonic acid to generate as major products: 8(R),9(S)-, 11(R),12(S)- and 14(S),15(R)-epoxyeicosatrienoic acids with optical purities of 97, 88, and 70%, respectively. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0dac50ec36034b72de42dc78290ce8d
https://doi.org/10.1016/s0021-9258(19)36671-2
https://doi.org/10.1016/s0021-9258(19)36671-2