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High Yield Preparation of Functionally Active Catalytic-Translocation Domain Module of Botulinum Neurotoxin Type A That Exhibits Uniquely Different Enzyme Kinetics

Autor: Bal Ram Singh, Kruti Patel, Raj Kumar, Nagarajan Thiruvanakarasu, Ghuncha Ambrin, Shouwei Cai, Harkiranpreet Kaur Dhaliwal

Botulinum neurotoxins (BoNTs) are the most toxic proteins known to cause flaccid muscle paralysis as a result of inhibition of neurotransmitter release from peripheral cholinergic synapses. BoNT type A (BoNT/A) is a 150 kDa protein consisting of two

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49a86a98657000da31ac1f872cae22c
https://europepmc.org/articles/PMC5705016/

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