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pro vyhledávání: '"Shouta Fujisawa"'
Characterization and optimization of two-chain folding pathways of insulin via native chain assembly
Autor:
Kenji Inaba, Hidekazu Katayama, Shouta Fujisawa, Reina Shinozaki, Setsuko Ando, Toshiki Takei, Masato Noguchi, Hironobu Hojo, Luis Moroder, Michio Iwaoka, Kenta Arai, Masaki Okumura
Publikováno v:
Communications Chemistry
Communications Chemistry, Vol 1, Iss 1, Pp 1-11 (2018)
Communications Chemistry, Vol 1, Iss 1, Pp 1-11 (2018)
Until recently the total synthesis of insulin, with its characteristic heterodimeric structure crosslinked by two interchain and one intrachain disulfide (SS) bridge, remained largely an unsolved challenge. By optimizing the synthesis and directed di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494d852b6071ab6dcfd3f35497602b7d
https://hdl.handle.net/21.11116/0000-0002-A4BB-221.11116/0000-0002-A4BD-0
https://hdl.handle.net/21.11116/0000-0002-A4BB-221.11116/0000-0002-A4BD-0