Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shouqi Luo"'
Autor:
Sujatha Kumar, Srimoyee Ghosh, Geeta Sharma, Zebin Wang, Marilyn R. Kehry, Margaret H. Marino, Tamlyn Y. Neben, Sharon Lu, Shouqi Luo, Simon Roberts, Sridhar Ramaswamy, Hadi Danaee, David Jenkins
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Inhibitors of programmed cell death protein 1 (PD-1) and its ligand (PD-L1) have dramatically changed the treatment landscape for patients with cancer. Clinical activity of anti-PD-(L)1 antibodies has resulted in increased median overall survival and
Externí odkaz:
https://doaj.org/article/9da6bd9d6003443393ec5b573b0b1c81
Autor:
Zebin Wang, Sharon Lu, Simon Roberts, Hadi Danaee, Tamlyn Y. Neben, Sujatha Kumar, Marino Margaret Habash, Srimoyee Ghosh, Sridhar Ramaswamy, David Jenkins, Marilyn Kehry, Shouqi Luo, Geeta Sharma
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Inhibitors of programmed cell death protein 1 (PD-1) and its ligand (PD-L1) have dramatically changed the treatment landscape for patients with cancer. Clinical activity of anti-PD-(L)1 antibodies has resulted in increased median overall survival and
Publikováno v:
Humanexperimental toxicology. 35(5)
The single- and repeat-dose toxicity profile of IDX14184, a novel guanosine nucleotide prodrug with antiviral activity against hepatitis C viral infection, was characterized following once daily oral administration for durations up to 13, 26, and 32
Autor:
Yves Merand, Van Luu-The, Claude Labrie, Shankar M. Singh, Alain Bélanger, Gilles Tremblay, Céline Martel, Fernand Labrie, Shouqi Luo, Sylvain Gauthier, Gilles Charpenet, Vincent Giguère, Ronald Charbonneau, Lionel Cusan, Agnès Coquet, Raymonde Veilleux, Virgile Richard, Jacques Simard, Bernard Candas, André J. Tremblay, Marc Fournier
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 69:51-84
Breast cancer is the most frequent cancer in women while it is the second cause of cancer death. Estrogens are well recognized to play the predominant role in breast cancer development and growth and much efforts have been devoted to the blockade of
Autor:
Shouqi Luo, Claude Labrie, Alain Bélanger, Fernand Labrie, Antigone Sourla, Yves Merand, Sylvain Gauthier
Publikováno v:
Endocrinology. 139:2645-2656
Treatment with the antiestrogen EM-800, at the daily oral dose of 3μ g, 10 μg, 30 μg, or 100 μg for 24 weeks, caused a marked inhibition of uterine and vaginal weight in both intact and ovariectomized mice. Maximal 64% and 41% inhibitions of uter
Publikováno v:
Breast Cancer Research and Treatment. 49:1-11
The effect of EM-800, a new non-steroidal antiestrogen having pure antiestrogenic activity, was studied on chemical carcinogenesis induced by dimethylbenz(a)anthracene (DMBA) as well as on serum lipids and bone mass in the rat. Treatment with EM-800
Publikováno v:
International Journal of Cancer. 73:580-586
The novel anti-estrogen EM-800 and medroxyprogesterone acetate (MPA) inhibit estrone (E1)-stimulated growth of dimethylbenz[a]anthracene (DMBA)-induced mammary tumors in a rat model. After 65 days, ovariectomy (OVX) decreased total tumor area to 9.6
Publikováno v:
Endocrinology. 138:4435-4444
Although treatment with dehydroepiandrosterone (DHEA) and the antiestrogen EM-800 alone decreased dimethylbenz(A)anthracene (DMBA)-induced mammary tumor incidence from 95% to 57% and 38%, respectively, approximately 9 months after DMBA administration
Autor:
Fernand Labrie, G LeBlanc, C. Labrie, Jacques Simard, A Bélanger, Shouqi Luo, C Martel, Bernard Candas, Shankar M. Singh
Publikováno v:
Endocrine Related Cancer. 3:229-241
Autor:
Shankar M. Singh, Céline Martel, Cailin Chen, Claude Labrie, Shouqi Luo, Bernard Cands, Fernand Labrie
Publikováno v:
Urology. 50(6)
Objectives Because the large increase in luteinizing hormone secretion induced by flutamide in the intact rat is not found in men, we have used castrated rats and mice supplemented with androstenedione (4-dione) instead of intact animals to measure t