Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Shounan Yi"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Porcine islets surviving the acute injury caused by humoral rejection and IBMIR will be subjected to cellular xenograft rejection, which is predominately mediated by CD4+ T cells and is characterised by significant infiltration of macrophages, B cell
Externí odkaz:
https://doaj.org/article/12bb05949bd04ebba9a8119115c4f7dd
Autor:
Xingxing An, Guangneng Liao, Younan Chen, Ai Luo, Jingping Liu, Yujia Yuan, Lan Li, Lichuan Yang, Hong Wang, Fang Liu, Guang Yang, Shounan Yi, Yuanmin Li, Jingqiu Cheng, Yanrong Lu
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-16 (2019)
Abstract Background Diabetic nephropathy (DN) is one of the most severe chronic diabetic complications and the main cause of end-stage renal disease. Chronic inflammation plays a key role in the development of DN. However, few treatment strategies ar
Externí odkaz:
https://doaj.org/article/3215e12f96ed4d7e8b93d7855ef8c368
Autor:
Xing He, Sang Li, Juan Zhang, Lu Cao, Cejun Yang, Pengfei Rong, Shounan Yi, Kedar Ghimire, Xiaoqian Ma, Wei Wang
Publikováno v:
Cell Transplantation, Vol 30 (2021)
The role of Regulatory T cells (Tregs) in tolerance induction post-transplantation is well-established, but Tregs adoptive transfer alone without combined immunosuppressants have failed so far in achieving clinical outcomes. Here we applied a set of
Externí odkaz:
https://doaj.org/article/e659ab66db8b4a19acc7749c40f3a0e1
Autor:
Elvira Jimenez Vera, Yi Vee Chew, Leigh Nicholson, Heather Burns, Patricia Anderson, Hsiao-Ting Chen, Lindy Williams, Karen Keung, Negar Talaei Zanjani, Suat Dervish, Ellis Patrick, Xin Maggie Wang, Shounan Yi, Wayne Hawthorne, Stephen Alexander, Philip J O'Connell, Min Hu
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217163 (2019)
Understanding the immunological phenotype of transplant recipients is important to improve outcomes and develop new therapies. Immunophenotyping of whole peripheral blood (WPB) by flow cytometry is a rapid method to obtain large amounts of data relat
Externí odkaz:
https://doaj.org/article/a1e416a56f2c4bc2993941ecd793b207
Autor:
Chengshi Wang, Xiaojiong Du, Sirong He, Yujia Yuan, Pengfei Han, Dan Wang, Younan Chen, Jingping Liu, Bole Tian, Guang Yang, Shounan Yi, Fabao Gao, Zhihui Zhong, Hongxia Li, Jingqiu Cheng, Yanrong Lu
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174505 (2017)
The bone marrow cavity (BMC) has recently been identified as an alternative site to the liver for islet transplantation. This study aimed to compare the BMC with the liver as an islet allotransplantation site in diabetic monkeys. Diabetes was induced
Externí odkaz:
https://doaj.org/article/14f058f87cd74f18b9a61255e9641ee7
Autor:
Ruxing Zhao, Dongqi Tang, Shounan Yi, Wenjuan Li, Chuanlong Wu, Yiran Lu, Xinguo Hou, Jun Song, Peng Lin, Li Chen, Lei Sun
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85770 (2014)
OBJECTIVE: Chronic low-grade inflammation has long been recognized as the central link between obesity and type 2 diabetes (T2D). The novel subset of T helper (Th) cells, Th22, plays an emerging role in chronic inflammation. We investigated the poten
Externí odkaz:
https://doaj.org/article/4c95037402164024a09e5c40504ac4c6
Autor:
Xiaoqian Ma, Bin Ye, Feng Gao, Qi Liang, Qiong Dong, Yin Liu, Pengfei Rong, Wei Wang M.D., Ph.D., Shounan Yi M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Tissue factor (TF) expression on islets has been shown to trigger instant blood-mediated inflammatory reaction (IBMIR), leading to rapid islet loss in portal vein islet transplantation. This study investigated whether antisense RNA-mediated TF gene k
Externí odkaz:
https://doaj.org/article/13f5992189c74aa9bb1d3ea14c2da38f
Autor:
Juan Zhang, Xiaoqian Ma, Lu Cao, Xing He, Sang Li, Min Yang, Cejun Yang, Pengfei Rong, Shounan Yi, Kedar Ghimire, Xiangfeng Kong, Wei Wang
Publikováno v:
Clin Exp Immunol
FOXP3+ regulatory T cells (Tregs) are central to maintaining peripheral tolerance and immune homeostasis. They have the potential to be developed as a cellular therapy to treat various clinical ailments such as autoimmune disorders, inflammatory dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96233a9666ddad88ca8c953d5206d5ca
https://doi.org/10.1093/cei/uxac035
https://doi.org/10.1093/cei/uxac035
Autor:
Karen Keung, Yi Vee Chew, Yi Wen Qian, Philip J. O'Connell, Wayne J. Hawthorne, Shounan Yi, Debbie Watson, Natasha M. Rogers, Lindy Williams, Stephen I. Alexander, David Liuwantara, Min Hu, Heather Burns, Leigh Nicholson, Elvira Jimenez Vera
Publikováno v:
Diabetes. 69:1735-1748
Islet transplantation is an emerging therapy for type 1 diabetes and hypoglycemic unawareness. However, a key challenge for islet transplantation is cellular rejection and the requirement for long-term immunosuppression. In this study, we established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::509ef85afda9ec5108ccd030c2de2b58
https://doi.org/10.2337/db19-0525
https://doi.org/10.2337/db19-0525
Autor:
Xiaoqian Ma, Kedar Ghimire, Wei Wang, Pengfei Rong, Lu Cao, Shounan Yi, Sang Li, Juan Zhang, Xing He, Cejun Yang
Publikováno v:
Cell Transplantation
Cell Transplantation, Vol 30 (2021)
Cell Transplantation, Vol 30 (2021)
The role of Regulatory T cells (Tregs) in tolerance induction post-transplantation is well-established, but Tregs adoptive transfer alone without combined immunosuppressants have failed so far in achieving clinical outcomes. Here we applied a set of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7202779350ae586b2b8f6eeb470e425
https://pubmed.ncbi.nlm.nih.gov/34570631
https://pubmed.ncbi.nlm.nih.gov/34570631