Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Shouliang Dong"'
Autor:
Yaofeng Zhao, Zhonghua Zhang, Dingnian Gou, Pengtao Li, Tong Yang, Zhanyu Niu, Jerine Peter Simon, Xuyan Guan, Xinyu Li, Chunbo He, Shouliang Dong
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 179, Iss , Pp 117389- (2024)
An important goal in the opioid field is to discover effective analgesic drugs with minimal side effects. MCRT demonstrated potent antinociceptive effects with limited side effects, making it a promising candidate. However, its pharmacological proper
Externí odkaz:
https://doaj.org/article/578624141d154bc280e6dbc47e885b6a
Publikováno v:
Sensors, Vol 20, Iss 6, p 1746 (2020)
Glutathione (GSH) is the main component of the mitochondrial thiol pool and plays key roles in the biological processes. Many evidences have suggested that cysteine and homocysteine also exist in mitochondria and are interrelated with GSH in biologic
Externí odkaz:
https://doaj.org/article/430a3876592543ecb5a06c55dd692b62
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141918 (2015)
A novel amino acid derivative 3-(4-(1, 2, 4, 5-tetrazine-3-yl) phenyl)-2-aminopropanoic acid was synthesized in this study. The compound possessed better water-solubility and was synthesized more easily compared with the well-known and commercially a
Externí odkaz:
https://doaj.org/article/0ccd7d08b4a947d9b801a9cab923285e
Autor:
Shouliang Dong, Hasan Sh. Majdi, As'ad Alizadeh, Russul Thaibat, Furqan S. Hashim, Hasan Mohammed Abdullah, Qusay Husam Aziz, Maboud Hekmatifar, Rozbeh Sabetvand
Publikováno v:
Journal of the Taiwan Institute of Chemical Engineers. 145:104781
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 98:691-699
Endokinin A/B (EKA/B), the common C-terminal decapeptide in endokinins A and B, is a preferred ligand of the NK1 receptor and regulates pain and itch. The study focused on the effects of EKA/B on rat gastric motility in vivo and in vitro. Gastric emp
Publikováno v:
Bioorganic Chemistry. 129:106221
Glutathione (GSH) level has long been recognized as a valuable tumor biomarker. GSH-mediated activation and release systems have been extensively developed for cancer diagnosis and treatment, but mainly focused on disulfide-based conjugate. We report
Autor:
Jing Zhang, Xiaoli Wang, Hao Wang, Yaofeng Zhao, Jagat Narayan Shah, Chan Ma, Lanxia Zhou, Hailan Li, Shouliang Dong, Chunbo He, Wenting Su, Shasha Chen, Zhe Zhang
Publikováno v:
Basicclinical pharmacologytoxicologyREFERENCES. 128(6)
Chimeric peptide MCRT (YPFPFRTic-NH2 ) was a multifunctional ligand of opioid and neuropeptide FF (NPFF) receptors and reported to be potentially antalgic in acute tail-flick test. Here, we developed spared nerve injury (SNI) model to explore its eff
Publikováno v:
Sensors
Volume 20
Issue 6
Sensors (Basel, Switzerland)
Sensors, Vol 20, Iss 6, p 1746 (2020)
Volume 20
Issue 6
Sensors (Basel, Switzerland)
Sensors, Vol 20, Iss 6, p 1746 (2020)
Glutathione (GSH) is the main component of the mitochondrial thiol pool and plays key roles in the biological processes. Many evidences have suggested that cysteine and homocysteine also exist in mitochondria and are interrelated with GSH in biologic
Publikováno v:
Bioscience Reports
The core of the tumor microenvironment in the hematological system is formed by bone marrow stromal cells (BMSCs). In the present study, we explored the interaction between the urokinase plasminogen activator (uPA) system and the leukemia bone marrow
Publikováno v:
Journal of Pharmacy and Pharmacology. 69:1244-1251
Objectives Chimeric peptide MCRT, based on morphiceptin and PFRTic-NH2, was a bifunctional ligand of μ- and δ-opioid receptors (MOR-DOR) and produced potent analgesia in tail-withdrawal test. The study focused on the supraspinal effects of morphice