Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Shouhai Wu"'
Autor:
Shouhai Wu, Cuiping Rong, Ruishan Lin, Kaiyuan Ji, Tongxiang Lin, Weimin Chen, Wei Mao, Yang Xu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPaBing-II Formula (PB-II) is a traditional Chinese medicine for treating Parkinson’s disease (PD). However, owing to the complexity of PB-II and the difficulty in obtaining human dopaminergic neurons (DAn), the mechanism of action of PB-I
Externí odkaz:
https://doaj.org/article/153f9207006b4ae0969a684d734cb4ca
Autor:
Delun Li, Yimeng Li, Xuesheng Chen, Jianting Ouyang, Danyao Lin, Qiaoru Wu, Xinwen Fu, Haohao Quan, Xiaowan Wang, Shouhai Wu, Siyu Yuan, Anqi Liu, Jiaxiong Zhao, Xiaowu Liu, Gangxing Zhu, Chuang Li, Wei Mao
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Objective(MSU) crystals usually in the kidney tubules especially collecting ducts in the medulla. Previous animal models have not fully reproduced the impact of MSU on kidneys under non-hyperuricemic conditions.MethodsIn the group treated with MSU, t
Externí odkaz:
https://doaj.org/article/80b47cf8c97e4066b2ba491663c0a9c8
Autor:
Shouhai Wu, Meixia Yan, Junyi Liu, Yizhen Li, Ruimin Tian, Chuang Li, Lihuang Huang, Zhisheng Lu, Peng Xu, Wei Mao
Publikováno v:
Pharmaceutical Biology, Vol 61, Iss 1, Pp 1274-1285 (2023)
AbstractContext Clerodendranthus spicatus Thunb. (Labiatae) (CS), a perennial traditional Chinese medicinal herb that can reduce serum uric acid (sUA) levels and ameliorate renal function is widely used to treat hyperuricaemic nephropathy (HN).Object
Externí odkaz:
https://doaj.org/article/2d3b5230d4c349809a1b4aa916c9e1b2
Autor:
Jianting Ouyang, Danyao Lin, Xuesheng Chen, Yimeng Li, Qin Liu, Delun Li, Haohao Quan, Xinwen Fu, Qiaoru Wu, Xiaowan Wang, Shouhai Wu, Chuang Li, Yi Feng, Wei Mao
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0304852 (2024)
BackgroundKnown for its strong diuretic properties, the perennial herbaceous plant Orthosiphon stamineus Benth. is believed to preserve the kidney disease. This study compared the boiling water extract with powdered Orthosiphon stamineus Benth. and u
Externí odkaz:
https://doaj.org/article/9400f983771b422b993c3cdcca38eaa2
Autor:
Shouhai Wu, Chuang Li, Yizhen Li, Junyi Liu, Cuiping Rong, Hongfei Pei, Xiong Li, Xiang Zeng, Wei Mao
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Introduction: The excretion and absorption of uric acid (UA) by the kidneys helps regulate serum UA levels. GLUT9, encoded by SLC2A9, is mainly expressed in the renal tubules responsible for UA absorption. SLC2A9 polymorphisms are associated with dif
Externí odkaz:
https://doaj.org/article/aa10e8ed77b148c6b68aa0a26c021f1b
Autor:
Delun Li, Siyu Yuan, Yiyao Deng, Xiaowan Wang, Shouhai Wu, Xuesheng Chen, Yimeng Li, Jianting Ouyang, Danyao Lin, Haohao Quan, Xinwen Fu, Chuang Li, Wei Mao
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Changes in lifestyle induce an increase in patients with hyperuricemia (HUA), leading to gout, gouty arthritis, renal damage, and cardiovascular injury. There is a strong inflammatory response in the process of HUA, while dysregulation of immune cell
Externí odkaz:
https://doaj.org/article/8dc09a66c4e0499da22527d1242a2996
Publikováno v:
Protein & Cell, Vol 11, Iss 1, Pp 71-78 (2019)
Abstract Pluripotent stem cells (PSCs) are capable of unlimited self-renewal in culture and differentiation into all functional cell types in the body, and thus hold great promise for regenerative medicine. To achieve their clinical potential, it is
Externí odkaz:
https://doaj.org/article/1e08c48dad744870b42c9d952aa0d6fb
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Are shorter telomeres causal risk factors for Alzheimer’s disease (AD)? This study aimed to examine if shorter telomeres were causally associated with a higher risk of AD using Mendelian randomization (MR) analysis. Two-sample MR methods were appli
Externí odkaz:
https://doaj.org/article/ca5deb2d03a34ce6b3de553cd6deb6ad
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189198 (2017)
Oxidative stress has been associated with diverse diseases, including obesity, cancer and neurodegeneration. In fact, Valeriana jatamansi Jones (valerian) and its extracts possess strong antioxidant activities that extend their application in clinica
Externí odkaz:
https://doaj.org/article/9ef9162ac01940faa1ed8832afd0a435
Autor:
Tongxiang Lin, Shouhai Wu
Publikováno v:
Stem Cells International, Vol 2015 (2015)
Induced pluripotent stem cells (iPSCs) could be employed in the creation of patient-specific stem cells, which could subsequently be used in various basic and clinical applications. However, current iPSC methodologies present significant hidden risks
Externí odkaz:
https://doaj.org/article/051bd72dec93451d81277527ee17ea59