Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Shouhai Gao"'
Autor:
Binghe Wang, Wenqian Yang, Johnny L. Carson, Weijuan Ni, Brent W. Weston, Shouhai Gao, Mengyuan Zhu, Vishnu Vardhan Reddy Karnati, Haiying Fan, Xingming Gao
Two fluorescent diboronic acid compounds (6a and 6b) with a dipeptide linker were synthesized as potential sensors for cell surface saccharide Lewis X (Le(X)). Compound 6a with a dipeptide (H-Asp-Ala-) as the linker was found to selectively label CHO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc4ea405bf9748ef780ec2a88127f19
Publikováno v:
Bioorganic Chemistry. 29:259-270
Boronic acids bind certain 1,2- and 1,3-diols with high affinity through reversible formation of boronate esters. They have been utilized as the recognition moiety for artificial receptors, particularly receptors for carbohydrates that have cis -diol
Autor:
John L. Carson, Xingming Gao, Binghe Wang, Vishnu Vardhan Reddy Karnati, Weijuan Ni, W.Borden Hooks, Shouhai Gao, Wenqian Yang, Brent W. Weston
Publikováno v:
ChemInform. 33
A series of fluorescent diboronic acids was synthesized in nine steps as potential sensors for sialyl Lewis X (sLex). The fluorescent binding studies of these sensors with sLex were carried out in a mixed aqueous solution. Compound 7e was found to sh
Autor:
Shouhai Gao, Binghe Wang, W.Borden Hooks, Haiying Fan, Wenqian Yang, Brent W. Weston, John L. Carson, Xingming Gao, Vishnu Vardhan Reddy Karnati, Weijuan Ni
Publikováno v:
Chemistrybiology. 11(4)
Carbohydrate antigens with subterminal fucosylation have been implicated in the development and progression of several cancers, including hepatocellular carcinoma (HCC). Fluorescent sensors targeting fucosylated carbohydrate antigens could potentiall
Autor:
Sabapathy Sankar, Shouhai Gao, Binghe Wang, Weijuan Ni, Wenqian Yang, Xingming Gao, Vishnu Vardhan Reddy Karnati
Publikováno v:
ChemInform. 34
A glucose selective diphenylboronic acid fluorescent sensor (10a) with a K(a) of 1472M(-1) has been synthesized and evaluated. This sensor shows a 43- and 49-fold selectivity for glucose over fructose and galactose, respectively. The binding affinity
Autor:
Shouhai Gao, Weijuan Ni, W.Borden Hooks, John L. Carson, Xingming Gao, Vishnu Vardhan Reddy Karnati, Brent W. Weston, Binghe Wang, Wenqian Yang
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(16)
A series of fluorescent diboronic acids was synthesized in nine steps as potential sensors for sialyl Lewis X (sLex). The fluorescent binding studies of these sensors with sLex were carried out in a mixed aqueous solution. Compound 7e was found to sh
Publikováno v:
ChemInform. 32
Publikováno v:
Bioorganic chemistry. 29(5)
The ability to custom-make fluorescent sensors for different analytes could have a tremendous impact in a variety of areas. Template-directed polymerization or molecular imprinting seems to be a promising approach for the preparation of high-affinity
Publikováno v:
Scopus-Elsevier
[formula: see text] The application of molecular imprinting in making fluorescent sensors has been hampered by the lack of suitable fluorescent tags, which would respond to the binding event with significant fluorescence intensity changes. We have de