Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Shougo Asanami"'
Autor:
Shougo Asanami, Kazuyuki Shimono
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 676:102-105
Species-level differences in response to micronucleus induction with haloperidol, a drug that can induce hypothermia, were investigated. Haloperidol was intraperitoneally (i.p.) administered to mice (12.5-50 mg/kg) and rats (25-100 mg/kg), and the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9ca7aa66b3abfd856023241142f692
https://doi.org/10.1016/j.mrgentox.2009.04.011
https://doi.org/10.1016/j.mrgentox.2009.04.011
Autor:
Kazuyuki Shimono, Shougo Asanami
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 471:81-86
We investigated micronucleus induction in rats treated with chlorpromazine and reserpine, drugs that induce hypothermia. We administered chlorpromazine (31.3--250mg/kg) or reserpine (500--2000 mg/kg) intraperitoneally and measured temperature rectall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14cef1d4cb359f091ec62ab93eb6e0e
https://doi.org/10.1016/s1383-5718(00)00119-4
https://doi.org/10.1016/s1383-5718(00)00119-4
Publikováno v:
The Journal of Toxicological Sciences. 24:113-121
This study aims to determine the pH that peripheral veins can tolerate. Intravenous nutrient solutions with different pHs (from 4.52 to 6.71) were infused into rabbit ear veins, and the veins were examined histopathologically. After 6-hr infusion at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3dfea05e02dd55cc2cc954d8a237ef7
https://doi.org/10.2131/jts.24.113
https://doi.org/10.2131/jts.24.113
Publikováno v:
Nutrition. 14:496-501
This study aimed to determine the osmolality that peripheral venous endothelial cells can tolerate and to clarify the relationship between tolerance osmolality and duration of infusion. Nutrient solutions of 539-917 mOsm/kg, prepared to have no acidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f526d9acf98cb853f04f149a8a4a16
https://doi.org/10.1016/s0899-9007(98)00037-9
https://doi.org/10.1016/s0899-9007(98)00037-9
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 413:7-14
We investigated the effect of hypothermia on micronucleus induction in mouse bone marrow cells. To induce hypothermia, we administered chlorpromazine, which was negative in an in vitro chromosome aberration test, at 3.13, 6.25, 12.5, 25, 50, and 100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2eb13fef34e4026f56a8c0c0769301
https://doi.org/10.1016/s1383-5718(98)00004-7
https://doi.org/10.1016/s1383-5718(98)00004-7
Publikováno v:
The Journal of Toxicological Sciences. 23:77-85
In this study, we investigated the phlebitic potentials of several infusion solutions for peripheral parenteral nutrition to clarify the effects of pH and osmolality on the development of infusion phlebitis. A 10% glucose solution with electrolytes (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4ef428ca91e8c6f4ad9226dd8aedf6
https://doi.org/10.2131/jts.23.77
https://doi.org/10.2131/jts.23.77
Publikováno v:
Mutation Research Letters. 347:73-78
To examine the suitability of using rat peripheral blood from animals used in subchronic toxicity studies for micronucleus analysis, we orally administered phenacetin or 6-mercaptopurine for 14 days to groups of six rats and compared their micronucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4376b07ab34d7f63a5eeef3026377e16
https://doi.org/10.1016/0165-7992(95)90073-x
https://doi.org/10.1016/0165-7992(95)90073-x
Publikováno v:
The Journal of toxicological sciences. 26(5)
We previously reported that both hyperthermia and hypothermia induced micronuclei in mouse bone marrow cells (Asanami and Shimono, 1997a, 1997b, 1999). To investigate the effects of temperature on chromosome aberration in vitro, we conducted chromoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9560404e202a6b05eed5d90f748b9065
https://pubmed.ncbi.nlm.nih.gov/11871128
https://pubmed.ncbi.nlm.nih.gov/11871128
Autor:
Dorothea K. Torous, Yasushi Kondo, Catherine Moore, Koji Kondo, Richard Marshall, Madoka Nakajima, Shuichi Hamada, Shigenari Ozawa, Makoto Hayashi, Norihide Asano, Koichi Osawa, James L. Weaver, Takeshi Morita, Hironobu Tamura, Ray Proudlock, Leonard M. Schechtman, Satoko Hosoya, David H. Blakey, Nobuhiro Yajima, Akihiro Wakata, Chiaki Namiki, Shougo Asanami, Sei-ichi Sato, Sizuyo Sutou, Seiichi Ito, Hiroyasu Shimada
Publikováno v:
Environmental and molecular mutagenesis. 37(2)
To examine whether micronucleus tests can be incorporated into general toxicology assays, we performed micronucleus tests applying the treatment protocols typically used in such assays. In this 13th Collaborative Study of the CSGMT, both rats and mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8e2cfa9fbdecc41fa3491234922a3e
https://pubmed.ncbi.nlm.nih.gov/11246216
https://pubmed.ncbi.nlm.nih.gov/11246216
Publikováno v:
Nutrition (Burbank, Los Angeles County, Calif.). 14(2)
To clarify conflicting clinical results that had been reported as to whether dilution is effective or not in reducing infusion phlebitis, this study was undertaken. We undertook two experiments with the different infusion conditions in rabbits to con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b635dbcd22ecadb972965e4cbf25aaa
https://pubmed.ncbi.nlm.nih.gov/9530653
https://pubmed.ncbi.nlm.nih.gov/9530653