Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Shoucang Shen"'
Publikováno v:
Journal of the Mechanical Behavior of Biomedical Materials. 91:91-98
To overcome the disadvantage of current antibiotic bone cements with low drug elution efficiency, the hollow nanostructured titanium-dioxide (TiO2) nanotubes (TNTs) were formulated with antibiotic loaded bone cement to create nano diffusion networks,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a98e6a09ffa3f014c4a7fb1010e0721f
https://doi.org/10.1016/j.jmbbm.2018.11.020
https://doi.org/10.1016/j.jmbbm.2018.11.020
Autor:
Shoucang Shen, Reginald B. H. Tan, Wai Kiong Ng, Wilson Wang, Poddar Kingshuk, Kumaran Letchmanan, Zhilong Shi
Publikováno v:
Journal of the Mechanical Behavior of Biomedical Materials. 72:163-170
The influence of mesoporous silica nanoparticles (MSNs) loaded with antibiotics on the mechanical properties of functional poly(methyl methacrylate)-(PMMA) based bone cements is investigated. The incorporation of MSNs to the bone cements (8.15 wt%) s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6663aef63f9131c7692754ad89734171
https://doi.org/10.1016/j.jmbbm.2017.05.003
https://doi.org/10.1016/j.jmbbm.2017.05.003
Publikováno v:
Advanced Powder Technology. 28:1316-1324
To improve the dissolution properties of poorly water soluble active pharmaceutical ingredients (APIs), a solvent-free melt-absorption process was applied to directly load the APIs into mesoporous SBA-15 silica powder as an amorphous solid dispersion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfe6ea7e045c970c1fc9cf38a42e0cf4
https://doi.org/10.1016/j.apt.2017.02.020
https://doi.org/10.1016/j.apt.2017.02.020
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 161
Biopharmaceutical properties of poorly water-soluble antimalarial drug, Artemisinin (ART), were improved by formulating amorphous solid dispersions with transglycosylated food additives (Hsp-G and Stevia-G) via co-spray drying. Both the formulated AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d991945ca28f69805ed8fe403115ea
https://pubmed.ncbi.nlm.nih.gov/29054047
https://pubmed.ncbi.nlm.nih.gov/29054047
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 155
The objective of this study is to enhance the dissolution rate, supersaturation and physicochemical stability of combination of two poorly water-soluble anti-malarial drugs, artemisinin (ART) and mefloquine (MFQ), by encapsulating them inside mesopor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a877ea209188bca461374570aaef66e
https://pubmed.ncbi.nlm.nih.gov/28499218
https://pubmed.ncbi.nlm.nih.gov/28499218
To enhance the therapeutic efficacy of oral dosage forms, the development and application of mesoporous excipients with pore size ranging 2–300 nm has attracted much attention from both academia and industry in recent years. As drug carriers, mesop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14891d47a0937461cddbc123a4f12b52
https://doi.org/10.1016/b978-0-323-47720-8.00024-9
https://doi.org/10.1016/b978-0-323-47720-8.00024-9
Publikováno v:
Powder Technology. 268:424-428
Slow dissolution rate is responsible for poor oral bioavailability of fenofibrate. This work aimed at synthesizing a redispersible and rapidly-dissolved fenofibrate nanoformulation by combination of antisolvent precipitation-in-microfluidics and spra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acbea0bd45331cded96476d6ef2e6e39
https://doi.org/10.1016/j.powtec.2014.08.053
https://doi.org/10.1016/j.powtec.2014.08.053
Preparation and application of monodispersed mesoporous submicron carbon particles as a drug carrier
Publikováno v:
Powder Technology. 261:241-249
Monodispersed mesoporous carbon (MMPC) submicron carbon particles have been fabricated by co-spray drying of SBA-15 submicron particles and sucrose, followed by carbonization in a nitrogen environment and removal of the hard SBA-15 template in NaOH s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47d3522b95add86f195ed1392135d321
https://doi.org/10.1016/j.powtec.2014.04.044
https://doi.org/10.1016/j.powtec.2014.04.044
Autor:
Kennan C. Marsh, Rajeev Gokhale, Reginald B. H. Tan, Wai Kiong Ng, David Cheng Thiam Tan, Steven A. Nowak, Anastasia Windy Irwan, Xueming Liu, Shiqi Hong, Leonard Chia, Shoucang Shen
Publikováno v:
Drug Delivery. 23:316-327
Encapsulation of drugs in mesoporous silica using co-spray drying process has been recently explored as potential industrial method. However, the impact of spray drying on manufacturability, physiochemical stability and bioavailability in relation to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0a9266cc46ff2e37d4329456a00c6f
https://doi.org/10.3109/10717544.2014.913323
https://doi.org/10.3109/10717544.2014.913323
Publikováno v:
International Journal of Pharmaceutics. 465:83-89
Utilization of sugars (e.g. lactose, sucrose) as matrix formers for spray drying of drug nanosuspensions is associated with two drawbacks: (1) sugars are incapable of preventing agglomeration of drug nanoparticles (NPs) in the suspension state; and (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f0c6748f7e3d75c50f0d6cf0fbc1da
https://doi.org/10.1016/j.ijpharm.2014.02.025
https://doi.org/10.1016/j.ijpharm.2014.02.025