Zobrazeno 1 - 10
of 13
pro vyhledávání: '"ShouTang Wang"'
Autor:
Xinyu Wu, Ruonan Liu, Zhongtian Zhang, Jie Yang, Xin Liu, Liqiang Jiang, Mengmeng Fang, Shoutang Wang, Liangxue Lai, Yuning Song, Zhanjun Li
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2002-2023 (2024)
Abstract Cerebral palsy (CP) is a prevalent neurological disorder that imposes a significant burden on children, families, and society worldwide. Recently, the RhoB p.S73F mutation was identified as a de novo mutation associated with CP. However, the
Externí odkaz:
https://doaj.org/article/a28d7bf44ab84ac38c6a8dcf9e0fc51c
Autor:
Shoutang Wang, Marco Colonna
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 2, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/fb9036be979c4be69133924a3c480fa4
Autor:
Shoutang Wang, Deshan Ren, Brahim Arkoun, Anna-Lila Kaushik, Gabriel Matherat, Yann Lécluse, Dominik Filipp, William Vainchenker, Hana Raslova, Isabelle Plo, Isabelle Godin
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Wang et al. use transcriptomic analysis to show that disruption of the transcription factor Lyl-1 in primitive macrophage progenitors results in defective differentiation that impacts on embryonic patterning and neurodevelopment. They also show that
Externí odkaz:
https://doaj.org/article/b0632c6c599e422eadabd6a0186dda22
Autor:
Marco Colonna, Shoutang WANG
Publikováno v:
Clinical and Translational Medicine. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a05d308c100d77edbaf95b70072e6de
https://doi.org/10.1002/ctm2.1200
https://doi.org/10.1002/ctm2.1200
Autor:
Simone Brioschi, Julia A. Belk, Vincent Peng, Martina Molgora, Patrick Fernandes Rodrigues, Khai M. Nguyen, Shoutang Wang, Siling Du, Wei-Le Wang, Gary E. Grajales-Reyes, Jennifer M. Ponce, Carla M. Yuede, Qingyun Li, John M. Baer, David G. DeNardo, Susan Gilfillan, Marina Cella, Ansuman T. Satpathy, Marco Colonna
Publikováno v:
Immunity. 56:1027-1045.e8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7cb105939c763b25d6363d01849d88e
https://doi.org/10.1016/j.immuni.2023.01.028
https://doi.org/10.1016/j.immuni.2023.01.028
Autor:
Shoutang Wang, Raki Sudan, Vincent Peng, Yingyue Zhou, Siling Du, Carla M. Yuede, Tingting Lei, Jinchao Hou, Zhangying Cai, Marina Cella, Khai Nguyen, Pietro L. Poliani, Wandy L. Beatty, Yun Chen, Siyan Cao, Kent Lin, Cecilia Rodrigues, Ali H. Ellebedy, Susan Gilfillan, Gordon D. Brown, David M. Holtzman, Simone Brioschi, Marco Colonna
Publikováno v:
Cell. 185(22)
Genetic studies have highlighted microglia as pivotal in orchestrating Alzheimer's disease (AD). Microglia that adhere to Aβ plaques acquire a transcriptional signature, "disease-associated microglia" (DAM), which largely emanates from the TREM2-DAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2518bade01cf27e82ea856c7902f272d
https://pubmed.ncbi.nlm.nih.gov/36306735
https://pubmed.ncbi.nlm.nih.gov/36306735
Autor:
Shoutang Wang, Marco Colonna
Publikováno v:
Journal of Leukocyte Biology. 106:219-227
Microglia are resident Mϕs of the CNS that play pleiotropic functions in brain development and homeostasis. Impaired microglial functions are thought to be involved in the onset and progression of various neurodevelopmental and neurodegenerative dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891e6b3b328050b2bee59eee0d0034c6
https://doi.org/10.1002/jlb.mr0818-319r
https://doi.org/10.1002/jlb.mr0818-319r
Autor:
Dawn Weishuhn, Simone Brioschi, Diana Cha, Marco Colonna, Daniel Yoo, Sara Rao, Samuel A. Hasson, Jodi Bradley, Peng Luan, Ian Foltz, Shilpa Sambashivan, Shoutang Wang, Daniel C. Ellwanger, Menno Van Lookeren Campagne, Susan Gilfillan, Palaniswami Rathanaswami, Ryan Case, Lydia Green, Zhifei Shao
Publikováno v:
Proc Natl Acad Sci U S A
Triggering receptor expressed on myeloid cells 2 (TREM2) sustains microglia response to brain injury stimuli including apoptotic cells, myelin damage, and amyloid β (Aβ). Alzheimer’s disease (AD) risk is associated with the TREM2(R47H) variant, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e7e2a0334e1a0bf5f3ff55b8cfd453
https://doi.org/10.1073/pnas.2017742118
https://doi.org/10.1073/pnas.2017742118
Autor:
Gabriel Matherat, Dominik Filipp, Hana Raslova, Shoutang Wang, Isabelle Godin, Anna-Lila Kaushik, Isabelle Plo, Yann Lécluse, Deshan Ren, William Vainchenker
During ontogeny, macrophages (MΦ) populations emerge in the Yolk Sac (YS) via two distinct progenitor waves, prior to hematopoietic stem cell development. MΦ-progenitors from the primitive/”early EMP” and transient-definitive/”late EMP” wav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28127af1db6f88983dde578bc0861996
https://doi.org/10.1101/2020.09.28.316570
https://doi.org/10.1101/2020.09.28.316570
Autor:
Adiljan Ibrahim, Santiago Viveros Salazar, Tina Schwabe, Marco Colonna, Ilaria Tassi, Siddiqui Omer Rizwan, Meer Mustafa, Philip Kong, Arnon Rosenthal, Herve Rhinn, Susan Gilfillan, Shoutang Wang, Hua Long, Carla M. Yuede, Michael E. Ward, Robert H. Paul
Publikováno v:
The Journal of Experimental Medicine
Wang et al. demonstrate that a mAb specific for the human microglial receptor TREM2 induces microglia proliferation, ameliorates Aβ-induced pathology in a mouse model of Alzheimer’s disease, and can be given safely in a first-in-human phase I clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1fec3d76840f743afe4b22eebc736ba
https://pubmed.ncbi.nlm.nih.gov/32579671
https://pubmed.ncbi.nlm.nih.gov/32579671