Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Shou P. Guan"'
Autor:
Jennifer P. Newman, Grace Y. Wang, Kazuhiko Arima, Shou P. Guan, Michael R. Waters, Webster K. Cavenee, Edward Pan, Edita Aliwarga, Siao T. Chong, Catherine Y. L. Kok, Berwini B. Endaya, Amyn A. Habib, Tomohisa Horibe, Wai H. Ng, Ivy A. W. Ho, Kam M. Hui, Tomasz Kordula, Paula Y. P. Lam
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Interleukin-13 receptor alpha 2 is highly expressed in glioblastoma multiforme but its role in this malignancy is unclear. Here the authors show that this receptor interacts with mutant EGFR, stimulating its kinase activity, thus inducing proliferati
Externí odkaz:
https://doaj.org/article/86a25a0c882247c39b38bbcac00ca539
Autor:
Aarthi Ravikrishnan, Indrik Wijaya, Eileen Png, Kern Rei Chng, Eliza Xin Pei Ho, Amanda Hui Qi Ng, Ahmad Nazri Mohamed Naim, Jean-Sebastien Gounot, Shou Ping Guan, Jasinda Lee Hanqing, Lihuan Guan, Chenhao Li, Jia Yu Koh, Paola Florez de Sessions, Woon-Puay Koh, Lei Feng, Tze Pin Ng, Anis Larbi, Andrea B. Maier, Brian K. Kennedy, Niranjan Nagarajan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract While rapid demographic changes in Asia are driving the incidence of chronic aging-related diseases, the limited availability of high-quality in vivo data hampers our ability to understand complex multi-factorial contributions, including gut
Externí odkaz:
https://doaj.org/article/847efc33d26e47edb08e63e509b16783
Autor:
Chang Cheng, W Eugene Ho, Fera Y Goh, Shou Ping Guan, Li Ren Kong, Wen-Qi Lai, Bernard P Leung, W S Fred Wong
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20932 (2011)
BACKGROUND: Phosphoinositide 3-kinase (PI3K)/Akt pathway is linked to the development of asthma. Anti-malarial drug artesunate is a semi-synthetic derivative of artemisinin, the principal active component of a medicinal plant Artemisia annua, and has
Externí odkaz:
https://doaj.org/article/97583af4ba884750a84169648efc068e
Autor:
Ivy A.W. Ho, Berwini Endaya, Catherine Y. L. Kok, Siao T. Chong, Paula Y.P. Lam, Kazuhiko Arima, Jennifer P. Newman, Kam M. Hui, Michael R. Waters, Edita Aliwarga, Edward Pan, Webster K. Cavenee, Tomohisa Horibe, Amyn A. Habib, Tomasz Kordula, Shou P. Guan, Grace Y. Wang, Wai Hoe Ng
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Nature Communications
Nature Communications
The interleukin-13 receptor alpha2 (IL-13Rα2) is a cancer-associated receptor overexpressed in human glioblastoma multiforme (GBM). This receptor is undetectable in normal brain which makes it a highly suitable target for diagnostic and therapeutic
Autor:
Catherine Y. L. Kok, Melvin L.K. Chua, Kevin L.M. Chua, Alan T.L. Lam, Shou P. Guan, Siao T. Chong, Jennifer P. Newman, Paula Y.P. Lam
Publikováno v:
FEBS Open Bio
The specific mechanism underlying the tumor tropism of human mesenchymal stem cells (MSCs) for cancer is not well defined. We previously showed that the migration potential of MSCs correlated with the expression and protease activity of matrix metall
Autor:
Shou P. Guan, Kam M. Hui, Kian Chuan Sia, Siao T. Chong, Alexander Y. F. Chung, Berwini Endaya, Catherine Y. L. Kok, Jennifer P. Newman, Bin B. Liu, Paula Y.P. Lam, Hung Huynh
Publikováno v:
Oncotarget
The epithelial cell adhesion molecule (EpCAM) is a type I transmembrane glycoprotein that is regarded as one of the markers for tumor initiating cells (TIC) in human hepatocellular carcinoma (HCC). Much work has been directed towards targeting these