Baicalein Induces G2/M Cell Cycle Arrest Associated with ROS Generation and CHK2 Activation in Highly Invasive Human Ovarian Cancer Cells

Autor: Tzu-Chao Chuang, Wei-Syun Shao, Shih-Chung Hsu, Shou-Lun Lee, Ming-Ching Kao, Vinchi Wang

Publikováno v: Molecules, Vol 28, Iss 3, p 1039 (2023)

Ovarian cancer is a lethal gynecological cancer because drug resistance often results in treatment failure. The CHK2, a tumor suppressor, is considered to be an important molecular target in ovarian cancer due to its role in DNA repair. Dysfunctional

Externí odkaz: https://doaj.org/article/cfd2cfceff464b119f9ad53f1da4db35

Perceptions and Reality of Antimicrobial Prescribing During the Transition to Comfort Measures Only at an Academic Medical Center

Autor: Jeffrey Larnard, Leslie Blackshear, Matthew Shou Lun Lee, Mary K Buss, Wendy Stead

Publikováno v: Open Forum Infectious Diseases. 10

Background Little is known about antimicrobial prescribing when patient care is transitioned to comfort measures only (CMO). We used a multidisciplinary survey and retrospective cohort study to gain insight into antimicrobial prescribing in this popu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ad39dd12dbaf957713d5c6c4d3eebdf4
https://doi.org/10.1093/ofid/ofac692

Growth-suppressive effect of berberine on endometrial carcinoma cells: Role of mitochondrial and PI3K/Akt pathway

Autor: Han-Peng Kuo, Yi-Jen Lee, Chih-Yu Hsu, Shou-Lun Lee, Shih-Chung Hsu, Tzu-Chao Chuang, Jah-Yao Liu, Chao-Lin Kuo, Chi-Tang Ho, Ming-Ching Kao

Publikováno v: Journal of Functional Foods, Vol 17, Iss , Pp 600-609 (2015)

Berberine is an isoquinoline alkaloid and a popular dietary supplement in the US market for lowering blood glucose and managing a healthy lipid profile. The anti-tumour activity of berberine is also known. Endometrial cancer is a gynecological malign

Externí odkaz: https://doaj.org/article/6c52dadf0ab5417c9ba4c0aa52682097

Patients who report night sweats.

Autor: Larnard, Jeffrey, Berry, Jonathan, Majety, Priyanka, Moeng, Letumile, Lille, Marianne, Shou Lun Lee, Matthew

Publikováno v: BMJ: British Medical Journal; 5/20/2023, Vol. 381 Issue 8383, p1-5, 5p

Erinacine A Prevents Lipopolysaccharide-Mediated Glial Cell Activation to Protect Dopaminergic Neurons against Inflammatory Factor-Induced Cell Death In Vitro and In Vivo

Autor: Shou-Lun Lee, Jing-Ya Hsu, Ting-Chun Chen, Chun-Chih Huang, Tzong-Yuan Wu, Ting-Yu Chin

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 810, p 810 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 810
International Journal of Molecular Sciences

Hericium erinaceus (HE) is a common edible mushroom consumed in several Asian countries and considered to be a medicinal mushroom with neuroprotective effects. Erinacine A (EA) is a bioactive compound in Hericium erinaceus mycelium (HEM) that has bee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1852a93578f104f39dfd726b2e641f1e
https://www.mdpi.com/1422-0067/23/2/810