Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Shotaro Kamata"'
Autor:
Shotaro Kamata, Akihiro Honda, Nonoka Kashiwagi, Ayumi Shimamura, Sayaka Yashiro, Yuna Komori, Aoi Hosoda, Noriyuki Akahoshi, Isao Ishii
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 624 (2024)
Three peroxisome proliferator-activated receptor subtypes, PPARα, PPAR(ß/)δ, and PPARγ, exert ligand-dependent transcriptional control in concert with retinoid X receptors (RXRs) on various gene sets harboring PPAR response elements (PPREs) in th
Externí odkaz:
https://doaj.org/article/e0100f18dab94f4cb159c0659b44680b
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1264 (2023)
The number of patients with nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH) is increasing globally and is raising serious concerns regarding the increasing medical and economic burden incurred for their treatment. The pro
Externí odkaz:
https://doaj.org/article/1c08f3f259e84fa99d6471d3aa221987
Autor:
Shotaro Kamata, Akihiro Honda, Ryo Ishikawa, Makoto Akahane, Ayane Fujita, Chihiro Kaneko, Saeka Miyawaki, Yuki Habu, Yui Shiiyama, Kie Uchii, Yui Machida, Takuji Oyama, Isao Ishii
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1523 (2023)
No therapeutic drugs are currently available for nonalcoholic steatohepatitis (NASH) that progresses from nonalcoholic fatty liver via oxidative stress-involved pathways. Three cognate peroxisome proliferator-activated receptor (PPAR) subtypes (PPAR
Externí odkaz:
https://doaj.org/article/0accaf46209a47e383198c9c9eddc003
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100364- (2021)
Summary: Peroxisome proliferator-activated receptors (PPARs) are nuclear receptor-type transcription factors with three subtypes (α, δ, and γ) that regulate cell differentiation and metabolism. Co-crystals of human PPARα-ligand-binding domain (LB
Externí odkaz:
https://doaj.org/article/53ce7e7731544411be941c2d5ade6d26
Autor:
Shotaro Kamata, Takuji Oyama, Kenta Saito, Akihiro Honda, Yume Yamamoto, Keisuke Suda, Ryo Ishikawa, Toshimasa Itoh, Yasuo Watanabe, Takahiro Shibata, Koji Uchida, Makoto Suematsu, Isao Ishii
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101727- (2020)
Summary: Most triacylglycerol-lowering fibrates have been developed in the 1960s–1980s before their molecular target, peroxisome proliferator-activated receptor alpha (PPARα), was identified. Twenty-one ligand-bound PPARα structures have been dep
Externí odkaz:
https://doaj.org/article/019e9a2e669140bd9f38f82355fbf354
Autor:
Shotaro Kamata, Junya Yamamoto, Haruka Ohtani, Yuka Tosaka, Sayumi Yoshikawa, Noriyuki Akahoshi, Isao Ishii
Publikováno v:
FEBS Open Bio, Vol 8, Iss 9, Pp 1524-1543 (2018)
Overnight fasting is a routine procedure before surgery in clinical settings. Intermittent fasting is the most common diet/fitness trend implemented for weight loss and the treatment of lifestyle‐related diseases. In either setting, the effects not
Externí odkaz:
https://doaj.org/article/ea059c6dca5b4c3eaed59c9be4cf3e32
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 357-368 (2015)
Dietary or caloric restriction confers various clinical benefits. Short‐term fasting of mice is a common experimental procedure that may involve systemic metabolic remodeling, which may significantly affect experimental outputs. This study evaluate
Externí odkaz:
https://doaj.org/article/3196b720ddc64784a50410a33c6d5c1f
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 535-541 (2015)
Cystathionine β‐synthase‐deficient (Cbs−/−) mice, an animal model for homocystinuria, exhibit hepatic steatosis and juvenile semilethality via as yet unknown mechanisms. The plasma protein profile ofCbs−/− mice was investigated by proteo
Externí odkaz:
https://doaj.org/article/4fb54efd06fa427cbfa40306e152f7d4
Autor:
Shotaro Kamata, Isao Ishii
Publikováno v:
YAKUGAKU ZASSHI. 141:1267-1274
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptor-type transcription factors that consist of three subtypes (α, γ, and β/δ) with distinct physiological functions and ligand recognition. PPARs regulate energy metabolism and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df9346a8b748c0ca4a4b8cd31a023c8
https://doi.org/10.1248/yakushi.21-00138
https://doi.org/10.1248/yakushi.21-00138
Autor:
Shotaro Kamata, Isao Ishii
Publikováno v:
Methods in Molecular Biology ISBN: 9781071628300
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18083a3256c0dd82af9582e9874b541a
https://doi.org/10.1007/978-1-0716-2831-7_16
https://doi.org/10.1007/978-1-0716-2831-7_16
