Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shotaro, Wani"'
Autor:
Ai Sugita, Ryoya Kano, Hiroyasu Ishiguro, Natsuki Yanagisawa, Soichiro Kuruma, Shotaro Wani, Aki Tanaka, Yoshiaki Tabuchi, Yoshiaki Ohkuma, Yutaka Hirose
Publikováno v:
Cells, Vol 13, Iss 20, p 1689 (2024)
Chemical modifications of cellular RNAs play key roles in gene expression and host defense. The cap-adjacent N6,2′-O-dimethyladenosine (m6Am) is a prevalent modification of vertebrate and viral mRNAs and is catalyzed by the newly discovered N6 meth
Externí odkaz:
https://doaj.org/article/e13f73404abe4261a76d08bd4171d61f
Autor:
Shotaro Wani, Masamichi Yuda, Yosuke Fujiwara, Masaya Yamamoto, Fumio Harada, Yoshiaki Ohkuma, Yutaka Hirose
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e106040 (2014)
In eukaryotes, the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) is composed of tandem repeats of the heptapeptide YSPTSPS, which is subjected to reversible phosphorylation at Ser2, Ser5, and Ser7 during the trans
Externí odkaz:
https://doaj.org/article/fbbf5f9672c241bb9c0eb72f9cb55845
Autor:
Yuma Ishigami, Mariko Kimura-Asami, Shotaro Wani, Keiko Hirota, Yutaka Suzuki, Eichi Watabe, Marina Togo-Ohno, Tsutomu Suzuki, Akiyoshi Fukamizu, Satomi Takei, Hidehito Kuroyanagi, Sharmin Hasan
Publikováno v:
The EMBO Journal. 40
Alternative splicing of pre-mRNAs can regulate gene expression levels by coupling with nonsense-mediated mRNA decay (NMD). In order to elucidate a repertoire of mRNAs regulated by alternative splicing coupled with NMD (AS-NMD) in an organism, we perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89a5fd8810b9d003cd59a02ae4121a9b
https://doi.org/10.15252/embj.2020106434
https://doi.org/10.15252/embj.2020106434
Autor:
Eichi, Watabe, Marina, Togo-Ohno, Yuma, Ishigami, Shotaro, Wani, Keiko, Hirota, Mariko, Kimura-Asami, Sharmin, Hasan, Satomi, Takei, Akiyoshi, Fukamizu, Yutaka, Suzuki, Tsutomu, Suzuki, Hidehito, Kuroyanagi
Publikováno v:
EMBO J
Alternative splicing of pre‐mRNAs can regulate gene expression levels by coupling with nonsense‐mediated mRNA decay (NMD). In order to elucidate a repertoire of mRNAs regulated by alternative splicing coupled with NMD (AS‐NMD) in an organism, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2aa3ad3070140afa75a54dc072dcc21d
https://pubmed.ncbi.nlm.nih.gov/34152017
https://pubmed.ncbi.nlm.nih.gov/34152017
Autor:
Seiji Yamamoto, Tokuyuki Yoshida, Yutaka Hirose, Akira Okui, Yoshiyuki Horiuchi, Yoshiaki Ohkuma, Aki Tanaka, Takashi Ito, Takao Inoue, Tomoko Hagihara, Shotaro Wani
Publikováno v:
Genes to Cells. 22:265-276
In eukaryotes, the Mediator complex has important roles in regulation of transcription by RNA polymerase II. Mediator is a large complex with more than 20 subunits that form head, middle, tail and CDK/cyclin modules. Among them, CDK8 and/or CDK19 (CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd3dc8393444b1afc935d680f33cc01
https://doi.org/10.1111/gtc.12475
https://doi.org/10.1111/gtc.12475
Publikováno v:
Journal of Biochemistry. Aug2016, Vol. 160 Issue 2, p111-120. 10p.
Publikováno v:
Journal of Biochemistry. 160:111-120
The C-terminal domain (CTD) of the RNA polymerase II (Pol II) large subunit contains tandem repeats of the heptapeptide, Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. The CTD is subject to dynamic phosphorylation during transcription, mainly at serine residues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7986c62d668f022b6b873aec7b439da
https://doi.org/10.1093/jb/mvw018
https://doi.org/10.1093/jb/mvw018
Autor:
Shotaro Wani, Mai Iizuka, Yumiko Yamasaki-Kato, Marina Togo-Ohno, Matteo Vatta, Taeko Naruse, Katherine G. Spoonamore, Akinori Kimura, Tomohiko Ai, Yuichi Hiraoka, Richard J. Kovacs, Rie Murayama, Takeshi Yamamoto, Takeharu Hayashi, Masumi Saito, Mariko Kimura-Asami, Hidehito Kuroyanagi
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
RBM20 is a major regulator of heart-specific alternative pre-mRNA splicing of TTN encoding a giant sarcomeric protein titin. Mutation in RBM20 is linked to autosomal-dominant familial dilated cardiomyopathy (DCM), yet most of the RBM20 missense mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb74ab83efb92cae5193a54562d6fb5
https://doi.org/10.1038/s41598-018-26624-w
https://doi.org/10.1038/s41598-018-26624-w
Autor:
Shotaro Wani, Hidehito Kuroyanagi
Publikováno v:
WIREs RNA. 8
A nematode Caenorhabditis elegans is an intron-rich organism and up to 25% of its pre-mRNAs are estimated to be alternatively processed. Its compact genomic organization enables construction of fluorescence splicing reporters with intact genomic sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90228b52a92979c2f49c5be36db7caaa
https://doi.org/10.1002/wrna.1428
https://doi.org/10.1002/wrna.1428
Publikováno v:
Drug discoveriestherapeutics. 8(6)
The C-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) is composed of tandem repeats of the heptapeptide Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. The CTD of Pol II undergoes reversible phosphorylation during the transcription cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6962847c8659ec4e026c97c68ac70ef1
https://pubmed.ncbi.nlm.nih.gov/25639305
https://pubmed.ncbi.nlm.nih.gov/25639305