Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Shota Kaseda"'
Autor:
Kohei Omachi, Shota Kaseda, Tsubasa Yokota, Misato Kamura, Keisuke Teramoto, Jun Kuwazuru, Haruka Kojima, Hirofumi Nohara, Kosuke Koyama, Sumio Ohtsuki, Shogo Misumi, Toru Takeo, Naomi Nakagata, Jian-Dong Li, Tsuyoshi Shuto, Mary Ann Suico, Jeffrey H. Miner, Hirofumi Kai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Metformin is widely used for the treatment of type 2 diabetes, and increasing numbers of studies have shown that metformin also ameliorates tumor progression, inflammatory disease, and fibrosis. However, the ability of metformin to improve n
Externí odkaz:
https://doaj.org/article/d6c03b25c7634eeda9e0874c08df981e
Autor:
Yuya Sannomiya, Shota Kaseda, Misato Kamura, Hiroshi Yamamoto, Hiroyuki Yamada, Masataka Inamoto, Jun Kuwazuru, Saki Niino, Tsuyoshi Shuto, Mary Ann Suico, Hirofumi Kai
Publikováno v:
Renal Failure, Vol 43, Iss 1, Pp 510-519 (2021)
Alport syndrome (AS) is a hereditary glomerular nephritis caused by mutation in one of the type IV collagen genes α3/α4/α5 that encode the heterotrimer COL4A3/4/5. Failure to form a heterotrimer due to mutation leads to the dysfunction of the glom
Externí odkaz:
https://doaj.org/article/28d44a4ee9d64770bbe74e7703793f73
Autor:
Misato Kamura, Tomohiko Yamamura, Kohei Omachi, Mary Ann Suico, Kandai Nozu, Shota Kaseda, Jun Kuwazuru, Tsuyoshi Shuto, Kazumoto Iijima, Hirofumi Kai
Publikováno v:
Kidney International Reports, Vol 5, Iss 5, Pp 718-726 (2020)
Introduction: Alport syndrome is a hereditary glomerulonephritis that results from the disruption of collagen α345(IV) heterotrimerization caused by mutation in COL4A3, COL4A4 or COL4A5 genes. Many clinical studies have elucidated the correlation be
Externí odkaz:
https://doaj.org/article/bdf5f8fc4dca439b84ccb1b4dfed6dc8
Autor:
Tsubasa Yokota, Kohei Omachi, Mary Ann Suico, Haruka Kojima, Misato Kamura, Keisuke Teramoto, Shota Kaseda, Jun Kuwazuru, Tsuyoshi Shuto, Hirofumi Kai
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0183959 (2017)
A seminal study recently demonstrated that bromide (Br-) has a critical function in the assembly of type IV collagen in basement membrane (BM), and suggested that Br- supplementation has therapeutic potential for BM diseases. Because salts of bromide
Externí odkaz:
https://doaj.org/article/3ae93002d9c9477bb7d49f7bdfe95c79
Autor:
Jun Kuwazuru, Mary Ann Suico, Kohei Omachi, Haruka Kojima, Misato Kamura, Shota Kaseda, Teppei Kawahara, Yuki Hitora, Hikaru Kato, Sachiko Tsukamoto, Mikiyo Wada, Toshifumi Asano, Shunsuke Kotani, Makoto Nakajima, Shogo Misumi, Yuya Sannomiya, Jun Horizono, Yuimi Koyama, Aimi Owaki, Tsuyoshi Shuto, Hirofumi Kai
Publikováno v:
Kidney360.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4943a1b056c79567c40dbe8e17e28a59
https://doi.org/10.34067/kid.0000000000000134
https://doi.org/10.34067/kid.0000000000000134
Autor:
Jian Dong Li, Misato Kamura, Haruka Kojima, Tsuyoshi Shuto, Kohei Omachi, Hirofumi Nohara, Shogo Misumi, Mary Ann Suico, Jun Kuwazuru, Jeffrey H. Miner, Kosuke Koyama, Sumio Ohtsuki, Keisuke Teramoto, Shota Kaseda, Toru Takeo, Tsubasa Yokota, Naomi Nakagata, Hirofumi Kai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Metformin is widely used for the treatment of type 2 diabetes, and increasing numbers of studies have shown that metformin also ameliorates tumor progression, inflammatory disease, and fibrosis. However, the ability of metformin to improve non-diabet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b89f186792b71383e279a761741580
https://doaj.org/article/d6c03b25c7634eeda9e0874c08df981e
https://doaj.org/article/d6c03b25c7634eeda9e0874c08df981e
Autor:
Shota Kaseda, Yuya Sannomiya, Jun Horizono, Jun Kuwazuru, Mary Ann Suico, Sayaka Ogi, Ryoko Sasaki, Hidetoshi Sunamoto, Hirohiko Fukiya, Hayato Nishiyama, Misato Kamura, Saki Niinou, Yuimi Koyama, Futoshi Nara, Tsuyoshi Shuto, Kazuhiro Onuma, Hirofumi Kai
Publikováno v:
Kidney360
BACKGROUND: Bardoxolone methyl activates nuclear factor erythroid 2–related factor 2 (Nrf2) via covalent binding and irreversible inhibition of Kelch-like ECH-associated protein 1 (Keap1), the negative regulator of Nrf2. Ongoing clinical trials of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3d502c89ec9099fd5c10558fc0c7bb
https://pubmed.ncbi.nlm.nih.gov/35721612
https://pubmed.ncbi.nlm.nih.gov/35721612
Autor:
Hirofumi Kai, Tatsuya Kondo, Mary Ann Suico, Tsubasa Yokota, Mariam Piruzyan, Keisuke Teramoto, Eiichi Araki, Tsuyoshi Shuto, Kohei Omachi, Yu Tsurekawa, Misato Kamura, Shota Kaseda
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Nephrotic syndrome (NS) is a renal disorder that is characterized by massive proteinuria, hypoalbuminemia and edema. One of the main causes of NS is focal segmental glomerulosclerosis (FSGS), which has extremely poor prognosis. Although steroids and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5424cabbed388687ec58c583e2a5d351
https://doi.org/10.1038/s41598-020-75761-8
https://doi.org/10.1038/s41598-020-75761-8
Autor:
Mary Ann Suico, Jun Kuwazuru, Kohei Omachi, Haruka Kojima, Shota Kaseda, Tsuyoshi Shuto, Hirofumi Kai
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:2-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c45fba761918414c65c5a70c7a2fb09
https://doi.org/10.1254/jpssuppl.96.0_2-b-p-161
https://doi.org/10.1254/jpssuppl.96.0_2-b-p-161