Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Shota Kasai"'
1
Visualizing the Adenylation Activities and Protein-Protein Interactions of Aryl Acid Adenylating Enzymes
Autor: Hideaki Kakeya, Shota Kasai, Genzoh Tanabe, Fumihiro Ishikawa
Publikováno v: ChemBioChem. 18:2199-2204
Structural and activity studies have revealed the dynamic and transient actions of carrier protein (CP) activity in primary and secondary metabolic pathways. CP-mediated interactions play a central role in nonribosomal peptide biosynthesis, serving a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c839f446f844e8baea0fe896f846b8
https://doi.org/10.1002/cbic.201700361
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3
Introduction of Japanese Association of Disaster Medicine (JADM) Disaster Medical Coordination Support Team
Autor: Tomohiko Mase, Hisayoshi Kondo, Shota Kasai, Yuichi Koido, Yoshiki Toyokuni
Publikováno v: Prehospital and Disaster Medicine. 34:s142-s142
Introduction:The Japanese Association for Disaster Medicine (JADM) Disaster Medical Coordination Support Team (DMCST) was formed in 2016 when Japan experienced Kumamoto earthquake to support other disaster medical assistance teams in terms of headqua
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2ed3ec7104c020d5ab2f0dc4003cb8b
https://doi.org/10.1017/s1049023x19003157
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6
A chemical proteomic probe for detecting native carrier protein motifs in nonribosomal peptide synthetases
Autor: Shota Kasai, Takehiro Suzuki, Hideaki Kakeya, Fumihiro Ishikawa, Naoshi Dohmae
Publikováno v: Chemical communications (Cambridge, England). 52(98)
Derivatization of a 5′-(vinylsulfonylaminodeoxy)adenosine scaffold with a clickable functionality provided an activity-based probe that was used to label native carrier protein (CP) motifs in nonribosomal peptide synthetases (NRPSs). When coupled w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c80a6fef645e0fc7586f96d820ed71
https://pubmed.ncbi.nlm.nih.gov/27869277
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7
Accurate Detection of Adenylation Domain Functions in Nonribosomal Peptide Synthetases by an Enzyme-linked Immunosorbent Assay System Using Active Site-directed Probes for Adenylation Domains
Autor: Hideaki Kakeya, Kengo Miyamoto, Shota Kasai, Fumihiro Ishikawa, Sho Konno
Publikováno v: ACS chemical biology. 10(12)
A significant gap exists between protein engineering and enzymes used for the biosynthesis of natural products, largely because there is a paucity of strategies that rapidly detect active-site phenotypes of the enzymes with desired activities. Herein
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4b3730f6031a781083632cd444bbc5
https://pubmed.ncbi.nlm.nih.gov/26474351
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8
Functional profiling of adenylation domains in nonribosomal peptide synthetases by competitive activity-based protein profiling
Autor: Hideaki Kakeya, Sho Konno, Shota Kasai, Fumihiro Ishikawa
Publikováno v: Chemical communications (Cambridge, England). 51(87)
We describe competitive activity-based protein profiling (ABPP) to accelerate the functional prediction and assessment of adenylation (A) domains in nonribosomal peptide synthetases (NRPSs) in proteomic environments. Using a library of sulfamoyloxy-l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ad3959343312e061ce16629be95cae
https://pubmed.ncbi.nlm.nih.gov/26365322
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