SAD-B Phosphorylation of CAST Controls Active Zone Vesicle Recycling for Synaptic Depression

Autor: Sumiko Mochida, Yamato Hida, Shota Tanifuji, Akari Hagiwara, Shun Hamada, Manabu Abe, Huan Ma, Misato Yasumura, Isao Kitajima, Kenji Sakimura, Toshihisa Ohtsuka

Publikováno v: Cell Reports, Vol 16, Iss 11, Pp 2901-2913 (2016)

Short-term synaptic depression (STD) is a common form of activity-dependent plasticity observed widely in the nervous system. Few molecular pathways that control STD have been described, but the active zone (AZ) release apparatus provides a possible

Externí odkaz: https://doaj.org/article/f666f1de962349539dbcc7ad73ff9e31

Transcriptome Analysis Reveals Differential Gene Expression between the Closing Ductus Arteriosus and the Patent Ductus Arteriosus in Humans

Autor: Tomoyuki Kojima, Yasuhiro Ichikawa, Toshihide Asou, Yuko Kato, Sayuki Oka, Tsuyoshi Tachibana, Utako Yokoyama, Shota Tanifuji, Junichi Saito, Etsuko Miyagi

Publikováno v: Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease, Vol 8, Iss 45, p 45 (2021)
Volume 8
Issue 4

The ductus arteriosus (DA) immediately starts closing after birth. This dynamic process involves DA-specific properties, including highly differentiated smooth muscle, sparse elastic fibers, and intimal thickening (IT). Although several studies have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2738dff0a79b7cbd1fb5629c84c5504e
http://europepmc.org/articles/PMC8073410

CaV2.2 (N-type) voltage-gated calcium channels are activated by SUMOylation pathways

Autor: Shota Tanifuji, Graeme S. Cottrell, Sumiko Mochida, Hong Lin, Gary J. Stephens, Helena Cimarosti, Vasco Silveirinha

Publikováno v: Cell Calcium. 93:102326

SUMOylation is an important post-translational modification process involving covalent attachment of SUMO (Small Ubiquitin-like MOdifier) protein to target proteins. Here, we investigated the potential for SUMO-1 protein to modulate the function of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f8eb710bcb066e85839f0968db82cfb
https://doi.org/10.1016/j.ceca.2020.102326

Kinetic Organization of Ca2+ Signals That Regulate Synaptic Release Efficacy in Sympathetic Neurons

Autor: Michinori Mori, Shota Tanifuji, Sumiko Mochida

Publikováno v: Molecular Pharmacology. 86:297-305

Calcium regulation of neurotransmitter release is essential for maintenance of synaptic transmission. However, the temporal and spatial organization of Ca(2+) dynamics that regulate synaptic vesicle (SV) release efficacy in sympathetic neurons is poo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f35f8304132747f49c0ce7de4afd04a
https://doi.org/10.1124/mol.114.094029

Dynamin Is a Key Molecule to Decode Action Potential Firing

Autor: Sumiko Mochida, Shota Tanifuji

Publikováno v: Presynaptic Terminals ISBN: 9784431551652

The maintenance of neurotransmission relies on the replenishment of synaptic vesicles (SVs) adapted to wide variations in the number and frequency of incoming action potentials (APs). A candidate mechanism for SV recycling indexed to AP firing activi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bcc26095e5874a60825243c1a9ab2700
https://doi.org/10.1007/978-4-431-55166-9_11