Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Shosuke Okamoto"'
Autor:
Megumi Yokoyama, Kikuo Onozaki, Masafumi Takeno, Miki Adachi, Satomi Chujyo, Yuko Waguri-Nagaya, Aki Hayashi, Takanobu Otsuka, Takemasa Takii, Kazuichi Hayakawa, Shosuke Okamoto, Keiji Miyazawa, Saotomo Itoh, Kyohei Yamada, Tomohiro Arakawa, Kunihiko Akita
Publikováno v:
Journal of Interferon & Cytokine Research. 33:297-307
Cigarette smoking is a major established environmental risk factor for rheumatoid arthritis (RA), and synoviocyte-derived proinflammatory cytokines are implicated in the pathogenesis of RA. We have reported that aryl hydrocarbon or cigarette smoke co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee8816f3d779ce5c3aadc34a4ea09bc
https://doi.org/10.1089/jir.2012.0107
https://doi.org/10.1089/jir.2012.0107
Autor:
Shosuke Okamoto, Kikuo Onozaki, Kyohei Yamada, Takemasa Takii, Kunihiko Akita, Miki Adachi, Kazuichi Hayakawa, Satomi Chujo, Saotomo Itoh
Publikováno v:
Biochemical and Biophysical Research Communications. 404:1088-1092
Cigarette smoking is a major environmental risk factor for rheumatoid arthritis (RA). However, the experimental bases supporting the etiological role of cigarette smoking in RA have not been fully provided. We have reported that cigarette smoke conde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7683182d9a38baa00aa10b1fb71afd88
https://doi.org/10.1016/j.bbrc.2010.12.118
https://doi.org/10.1016/j.bbrc.2010.12.118
Autor:
Kikuo Onozaki, Satomi Chujo, Takemasa Takii, Kazuichi Hayakawa, Ryohei Sunahara, Kyohei Yamada, Miki Adachi, Shosuke Okamoto, Hidetoshi Hayashi
Publikováno v:
International Immunopharmacology. 10:1194-1199
Although cigarette smoking is a solid environmental risk factor for rheumatoid arthritis (RA) as revealed by epidemiological studies, the scientific basis has not been provided. Proinflammatory cytokines produced by synoviocytes are implicated in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa4d2f0eae9c995b7ac023dcc62bb10
https://doi.org/10.1016/j.intimp.2010.06.026
https://doi.org/10.1016/j.intimp.2010.06.026
Autor:
Shosuke OKAMOTO, Utako OKAMOTO
Publikováno v:
Japanese Journal of Thrombosis and Hemostasis. 13:259-266
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39b68b3026d33fc026cdfdee46c83932
https://doi.org/10.2491/jjsth.13.259
https://doi.org/10.2491/jjsth.13.259
Autor:
Shosuke Okamoto, Yoshio Okada, Yuko Tsuda, Utako Okamoto, Mayako Tada, Keiko Wanaka, Akiko Hijikata-Okunomiya
Publikováno v:
Chemical and Pharmaceutical Bulletin. 49:1457-1463
Based on the structure of Tra-Tyr(O-Pic)-octylamide, a portion of the octylamine was replaced with moieties bearing hydrophobic, basic or acidic groups. Replacement of the C-terminal residue with a moiety bearing a hydrophobic group gave the proper a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09bf4cbcaefcce78c62766c747aa18f
https://doi.org/10.1248/cpb.49.1457
https://doi.org/10.1248/cpb.49.1457
Autor:
Akiko Hijikata-Okunomiya, Yoshio Okada, Mayako Tada, Atsuko Fukumizu, Keiko Wanaka, Yoko Tsuda, Shosuke Okamoto
Publikováno v:
Chemical and Pharmaceutical Bulletin. 47:1141-1144
Pseudo-peptide analogs of trans-4-aminomethylcyclohexanecarbonyl-L-phenylalanyl-4-aminopheny l acetic acid (PKSI-527, plasma kallikrein selective inhibitor), in which an amide bond (peptide bond) has been replaced by a CH2-NH bond, i.e., trans-4-amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8baf6ee956cc9e513bc78e82ec816023
https://doi.org/10.1248/cpb.47.1141
https://doi.org/10.1248/cpb.47.1141
Autor:
Yoshio Okada, Shosuke Okamoto, Yuko Tsuda, Utako Okamoto, Mayako Tada, Akiko Hijikata-Okunomiya, Keiko Wanaka
Publikováno v:
Biopolymers. 51:41-50
During the course of the development of active center-directed plasmin inhibitors, it was found that N-(trans-4-aminomethylcyclohexanecarbonyl)-lysine-4-methoxycarbonylanilide inhibited plasma kallikrein more potently than other enzymes such as plasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283403b09c2bf7ab1ffb8ef538c761c9
https://doi.org/10.1002/(sici)1097-0282(1999)51:1<41::aid-bip5>3.0.co
https://doi.org/10.1002/(sici)1097-0282(1999)51:1<41::aid-bip5>3.0.co
Autor:
Keiko Wanaka, Yuko Tsuda, Akiko Hijikata-Okunomiya, Noburo Horie, Yoshio Okada, Utako Okamoto, Yukiko Nakaya, Shosuke Okamoto, Mayako Tada
Publikováno v:
Biological and Pharmaceutical Bulletin. 21:105-108
We synthesized a new affinity gel (PKSI-Toyopearl) using a selective synthetic inhibitor of plasma kallikrein (PKSI-527) as an affinity ligand, and employed it for the rapid purification of plasma kallikrein from human plasma. Human plasma activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca84be359cf3be06f322d420c923d2af
https://doi.org/10.1248/bpb.21.105
https://doi.org/10.1248/bpb.21.105
Autor:
Shosuke, Okamoto
Publikováno v:
研究論集 = Journal of Inquiry and Research. 61:315-331
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::e13360923f854a784a988afa2b890f39
http://id.nii.ac.jp/1443/00006799/
http://id.nii.ac.jp/1443/00006799/
Autor:
Shosuke, Okamoto
Publikováno v:
研究論集 = Journal of Inquiry and Research. 59:265-279
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::a6305a472bed51575a253138691915bd
http://id.nii.ac.jp/1443/00006862/
http://id.nii.ac.jp/1443/00006862/