Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shoshanna C, Kahne"'
Autor:
Shoshanna C. Kahne, Tierra Ouellette, Priya Saha, Huilin Li, Michael Foley, Toshihiro Imaeda, Kazuyoshi Aso, Ryoma Hara, K. Heran Darwin, Carl Nathan, Masanori Kawasaki, Akinori Toita, Wenhu Zhan, Francesca Moraca, Gang Lin, Jeremie Vendome, Takafumi Yukawa, John Ginn, Xiuju Jiang, Mayako Michino, Kenjiro Sato, Peter T. Meinke, Hao Zhang, Kristin Burns-Huang, Rei Okamoto, Tzu-Tshin Wong, Hao-Chi Hsu
Publikováno v:
Journal of Medicinal Chemistry. 64:6262-6272
Treatment of tuberculosis (TB) currently takes at least 6 months. Latent Mycobacterium tuberculosis (Mtb) is phenotypically tolerant to most anti-TB drugs. A key hypothesis is that drugs that kill nonreplicating (NR) Mtb may shorten treatment when us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49ac426b4c19d0fdaa3f695a2619ad2e
https://doi.org/10.1021/acs.jmedchem.1c00296
https://doi.org/10.1021/acs.jmedchem.1c00296
Publikováno v:
Journal of Biological Chemistry. 298:102478
Mycobacteria use a proteasome system that is similar to a eukaryotic proteasome but do not use ubiquitin to target proteins for degradation. Instead, mycobacteria encode a prokaryotic ubiquitin-like protein (Pup) that posttranslationally modifies pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99cdaa2c845bd2df3c9f2610fab424da
https://doi.org/10.1016/j.jbc.2022.102478
https://doi.org/10.1016/j.jbc.2022.102478
Autor:
Hao, Zhang, Hao-Chi, Hsu, Shoshanna C, Kahne, Ryoma, Hara, Wenhu, Zhan, Xiuju, Jiang, Kristin, Burns-Huang, Tierra, Ouellette, Toshihiro, Imaeda, Rei, Okamoto, Masanori, Kawasaki, Mayako, Michino, Tzu-Tshin, Wong, Akinori, Toita, Takafumi, Yukawa, Francesca, Moraca, Jeremie, Vendome, Priya, Saha, Kenjiro, Sato, Kazuyoshi, Aso, John, Ginn, Peter T, Meinke, Michael, Foley, Carl F, Nathan, K Heran, Darwin, Huilin, Li, Gang, Lin
Publikováno v:
J Med Chem
Treatment of tuberculosis (TB) currently takes at least 6 months. Latent Mycobacterium tuberculosis (Mtb) are phenotypically tolerant to most anti-TB drugs. A key hypothesis is that drugs that kill non-replicating (NR) Mtb may shorten treatment when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9ddc822052e96f40a4907042b230377
https://pubmed.ncbi.nlm.nih.gov/33949190
https://pubmed.ncbi.nlm.nih.gov/33949190
Autor:
K. Heran Darwin, Shoshanna C. Kahne
Publikováno v:
Curr Opin Struct Biol
Bacteria use gated proteolytic machines for routine protein quality control and regulated responses to environmental conditions. This review discusses recent advances in understanding the structure and regulation of ClpP proteases, nanomachines widel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db3f523068578abdf979f23dc38fd05
https://pubmed.ncbi.nlm.nih.gov/33221704
https://pubmed.ncbi.nlm.nih.gov/33221704
Autor:
Roberto C. Molina-Quiroz, Y Nguyen, Cecilia A. Silva-Valenzuela, Andrew Camilli, David W. Lazinski, Shoshanna C. Kahne
Publikováno v:
The ISME Journal. 11:2718-2728
Vibrio cholerae is a water-borne bacterial pathogen and causative agent of cholera. Although V. cholerae is a halophile, it can survive in fresh water, and this has a major role in cholera epidemics through consumption of contaminated water and subse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e9d6f04ff33b1d58363d7581349e68
https://doi.org/10.1038/ismej.2017.121
https://doi.org/10.1038/ismej.2017.121
Autor:
Richard J. Harrison, Steven M. Bogdanowicz, Crista B. Wadsworth, Genevieve M. Kozak, Brad S. Coates, Erik B. Dopman, Shoshanna C. Kahne
Genetic variation in life-history timing allows populations to synchronize with seasonal cycles but little is known about the molecular mechanisms that produce differences in circannual rhythm in nature. Changes in diapause timing in the European cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8d2af2bd56a24f9cd1bf053f3183df
https://doi.org/10.1101/633362
https://doi.org/10.1101/633362
Autor:
Brad S. Coates, Genevieve M. Kozak, Richard J. Harrison, Steven M. Bogdanowicz, Erik B. Dopman, Crista B. Wadsworth, Shoshanna C. Kahne
Publikováno v:
Molecular ecology. 26(8)
Chromosomal rearrangements between sympatric species often contain multiple loci contributing to assortative mating, local adaptation and hybrid sterility. When and how these associations arise during the process of speciation remains a subject of de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715a8e7d1e3654fa7b75205ce5ee0c4a
https://pubmed.ncbi.nlm.nih.gov/28141898
https://pubmed.ncbi.nlm.nih.gov/28141898