Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Shoshana Spring"'
Autor:
Juan M. Godoy-Corchuelo, Zeinab Ali, Jose M. Brito Armas, Aurea B. Martins-Bach, Irene García-Toledo, Luis C. Fernandez-Beltrán, Juan I. Lopez-Carbonero, Pablo Bascunana, Shoshana Spring, Irene Jimenez-Coca, Ramón A. Muñozde Bustillo Alfaro, Maria J. Sanchez-Barrena, Remya R. Nair, Brian J. Nieman, Jason P. Lerch, Karla L. Miller, Hande P. Ozdinler, Elizabeth M.C. Fisher, Thomas J. Cunningham, Abraham Acevedo-Arozena, Silvia Corrochano
Publikováno v:
Neurobiology of Disease, Vol 202, Iss , Pp 106708- (2024)
Externí odkaz:
https://doaj.org/article/418fc08c4bb144dfbd73a56508341368
Autor:
Juan M. Godoy-Corchuelo, Zeinab Ali, Jose M. Brito Armas, Aurea B. Martins-Bach, Irene García-Toledo, Luis C. Fernández-Beltrán, Juan I. López-Carbonero, Pablo Bascuñana, Shoshana Spring, Irene Jimenez-Coca, Ramón A. Muñoz de Bustillo Alfaro, Maria J. Sánchez-Barrena, Remya R. Nair, Brian J. Nieman, Jason P. Lerch, Karla L. Miller, Hande P. Ozdinler, Elizabeth M.C. Fisher, Thomas J. Cunningham, Abraham Acevedo-Arozena, Silvia Corrochano
Publikováno v:
Neurobiology of Disease, Vol 193, Iss , Pp 106437- (2024)
TDP-43 pathology is found in several neurodegenerative disorders, collectively referred to as “TDP-43 proteinopathies”. Aggregates of TDP-43 are present in the brains and spinal cords of >97% of amyotrophic lateral sclerosis (ALS), and in brains
Externí odkaz:
https://doaj.org/article/76599e797bbd49ac8a63e0a6d72160dc
Autor:
Zeinab Ali, Juan M. Godoy-Corchuelo, Aurea B. Martins-Bach, Irene Garcia-Toledo, Luis C. Fernández-Beltrán, Remya R. Nair, Shoshana Spring, Brian J. Nieman, Irene Jimenez-Coca, Rasneer S. Bains, Hamish Forrest, Jason P. Lerch, Karla L. Miller, Elizabeth M. C. Fisher, Thomas J. Cunningham, Silvia Corrochano
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/3f0a2c5de56a43eca3efee6113651e7a
Autor:
Hannah George, Grace V. Mercer, Darcie Stapleton, Laura Dawson, Phillip E. MacCallum, Shoshana Spring, John G. Sled, Jacqueline Blundell, Lindsay S. Cahill
Publikováno v:
Brain and Behavior, Vol 12, Iss 11, Pp n/a-n/a (2022)
Abstract Introduction Endothelial nitric oxide synthase (eNOS) produces nitric oxide, which is essential for a variety of physiological functions in the brain. Previous work has demonstrated the detrimental effects of eNOS deficiency on brain functio
Externí odkaz:
https://doaj.org/article/26d5513ff5bb439a8e95de616bcb1784
Autor:
Michelle Zuo, Naomi M. Fettig, Louis-Philippe Bernier, Elisabeth Pössnecker, Shoshana Spring, Annie Pu, Xianjie I. Ma, Dennis S.W. Lee, Lesley A. Ward, Anshu Sharma, Jens Kuhle, John G. Sled, Anne-Katrin Pröbstel, Brian A. MacVicar, Lisa C. Osborne, Jennifer L. Gommerman, Valeria Ramaglia
Publikováno v:
JCI Insight, Vol 7, Iss 12 (2022)
People living with multiple sclerosis (MS) experience episodic CNS white matter lesions instigated by autoreactive T cells. With age, patients with MS show evidence of gray matter demyelination and experience devastating nonremitting symptomology. Wh
Externí odkaz:
https://doaj.org/article/3179dda5d85f4c3d98777afc0ce6961d
Autor:
Darren J. Fernandes, Shoshana Spring, Anna R. Roy, Lily R. Qiu, Yohan Yee, Brian J. Nieman, Jason P. Lerch, Mark R. Palmert
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Maternal environmental exposures, such as high-fat diets, diabetes and obesity, can induce long-term effects in offspring. These effects include increased risk of neurodevelopmental disorders (NDDs) including autism spectrum disorder (ASD),
Externí odkaz:
https://doaj.org/article/d97b5868a8fe46028363b423214433bb
Autor:
Hirotaka Tao, Min Zhu, Kimberly Lau, Owen K. W. Whitley, Mohammad Samani, Xiao Xiao, Xiao Xiao Chen, Noah A. Hahn, Weifan Liu, Megan Valencia, Min Wu, Xian Wang, Kelli D. Fenelon, Clarissa C. Pasiliao, Di Hu, Jinchun Wu, Shoshana Spring, James Ferguson, Edith P. Karuna, R. Mark Henkelman, Alexander Dunn, Huaxiong Huang, Hsin-Yi Henry Ho, Radhika Atit, Sidhartha Goyal, Yu Sun, Sevan Hopyan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Morphogenesis of tissue sheets is well studied, but mechanisms that shape bulk tissues are unclear. Here, the authors show that mesenchymal cells intercalate in 3D to shape the mouse branchial arch, with cortical forces driving intercalations in a Wn
Externí odkaz:
https://doaj.org/article/a1919169bcc7429c80847ae4da278f58
Autor:
Ellinore R. Doroshenko, Paulina C. Drohomyrecky, Annette Gower, Heather Whetstone, Lindsay S. Cahill, Milan Ganguly, Shoshana Spring, Tae Joon Yi, John G. Sled, Shannon E. Dunn
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Peroxisome proliferator-activated receptor (PPAR)-δ is a nuclear receptor that functions to maintain metabolic homeostasis, regulate cell growth, and limit the development of excessive inflammation during immune responses. Previously, we reported th
Externí odkaz:
https://doaj.org/article/347a98b58b624f6a99e35593d835cc6d
Autor:
Elisa Guma, Emily Snook, Shoshana Spring, Jason P. Lerch, Brian J. Nieman, Gabriel A. Devenyi, M. Mallar Chakravarty
Publikováno v:
NeuroImage: Clinical, Vol 32, Iss , Pp 102868- (2021)
Prenatal exposure to maternal immune activation (MIA) is a risk factor for a variety of neurodevelopmental and psychiatric disorders. The timing of MIA-exposure has been shown to affect adolescent and adult offspring neurodevelopment, however, less i
Externí odkaz:
https://doaj.org/article/07e124d91a5848289b88f45d5e293cc3
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84321 (2013)
The International Mouse Phenotyping Consortium has been established to conduct large-scale phenotyping of the approximately 23,000 single-gene knockout mice generated by the International Knockout Mouse Consortium to investigate the role of each gene
Externí odkaz:
https://doaj.org/article/a0c659ee3ffd45148497f68e100199e5