Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shoshana Keynan"'
Autor:
Michael Bursztyn, Itamar Raz, Shoshana Keynan, Rachel Dahan, Etti Reinhartz, Haim Ovadia, Mogher Khamaisi
Publikováno v:
Nephron Physiology. 102:p72-p80
Background: Several studies have suggested that an early increase in renal nitric oxide (NO) production or activity mediates pathophysiologic and morphologic changes in diabetic nephropathy. To evaluate the role of NO in developing diabetic kidney di
Autor:
Rachel Dahan, Shoshana Keynan, Kay Barnes, Mogher Khamaisi, Anthony J. Turner, Itamar Raz, Carolyn D. Jackson
Publikováno v:
Journal of Vascular Research. 41:131-140
Endothelin-1 (ET-1) is both a potent vasoconstrictor and mitogenic factor that has been implicated as a cause of the micro- and macrovascular complications of diabetes mellitus. The pathway by which the high-glucose environment of diabetes mediates i
Publikováno v:
FEBS Letters. 349:50-54
Pig renal membrane dipeptidase cDNA has been expressed in COS-1 cells. Directed mutagenesis was used to investigate the roles of some conserved histidyl and aspartyl residues. Mutation of His219 to Arg, Lys or Leu results in complete abolition of enz
Autor:
Andanthony J. Turner, Nigel M. Hooper, Shoshana Keynan, Antonio Felici, Gianfranco Amicosante
Publikováno v:
Antimicrobial Agents and Chemotherapy. 39:1629-1631
The Aeromonas hydrophila AE036 chromosome contains a cphA gene encoding a metallo-beta-lactamase which is highly active against carbapenem antibiotics such as imipenem. Here we show that the cphA gene product shares inhibitory similarities with a mam
Autor:
Rachel Dahan, Boaz Hirshberg, Etty Reinhartz, Haim Ovadia, Adrian Iaina, Yoram Wollman, Isaiah D. Wexler, Tamara Chernihovskey, Shoshana Keynan, Nomy Levin-Iaina, Itamar Raz
Publikováno v:
Kidney international. 58(2)
Renal nitric oxide production during the early phase of experimental diabetes mellitus. Background Diabetic nephropathy (DN) is characterized by hyperfiltration and hypertrophy in experimental models of diabetes mellitus (DM). Several studies have de
Autor:
Doron Schwartz, Roland C. Blantz, Miriam Blum, Shoshana Keynan, Yoram Wolman, Kobi Sade, Idit F. Schwartz, Itamar Raz, Eli Brazowski, Adrian Iaina, Tamara Chernichovski
Publikováno v:
The Journal of laboratory and clinical medicine. 134(5)
The decrease in glomerular filtration rate that is characteristic of sepsis has been shown to result from the local glomerular inhibition of endothelial nitric oxide synthase (NOS) by nitric oxide (NO) generated from the inducible isoform of NOS (iNO
Publikováno v:
Oncogene. 15(10)
Membrane dipeptidase (MDP) is a zinc metalloenzyme located in the lungs and on the brush border membranes of the kidney and intestine. The gene for MDP (also termed DPEP1) is both frequently lost in Wilm's tumours and is located on human chromosome 1
Publikováno v:
The Biochemical journal. 326
Membrane dipeptidase (EC 3.4.13.19) is a plasma membrane zinc peptidase that is involved in the renal metabolism of glutathione and its conjugates, such as leukotriene D4. The enzyme lacks the classical signatures of other zinc-dependent hydrolases a
Publikováno v:
Biochemistry. 35(38)
Membrane dipeptidase (EC 3.4.13.19) is a glycosylphosphatidylinositol-anchored glycoprotein of the renal brush border which exists as a disulfide-linked homodimer. Porcine membrane dipeptidase has a subunit M(r) of 47 kDa, and the mature protein cont
Autor:
Mogher Khamaisi, Martine Lelièvre-Pégorier, Shigeaki Muto, Rachel Dahan, Jacques Marti, Shuichi Tsuruoka, David Piquemal, Itamar Raz, Ken-ichiro Kosai, Hisayoshi Fujiwara, Tomoyo Kagawa, Isabelle Guinobert, Selma Cirrik, Mélanie Viltard, Etti Reinhartz, Eiji Kusano, Masayasu Esaki, Yukio Miyata, Tomoyuki Takahashi, Akio Fujimura, Hiroshige Ohashi, Takako Fujiwara, Takamasa Ohno, Jean-Marc Elalouf, Shoshana Keynan, Gülsen Öner, Ichijiro Murata, Haim Ovadia, Rumi Maruyama, Michael Bursztyn, Genzou Takemura
Publikováno v:
Nephron Physiology. 102:p104-p104