Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Shoshana, Eitan"'
Autor:
Roanna A. Debler, Caitlin A. Madison, Lauren Hillbrick, Paula Gallegos, Stephen Safe, Robert S. Chapkin, Shoshana Eitan
Publikováno v:
Journal of Affective Disorders. 333:409-419
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38a938e201ea0b1d2c439603fbef1db9
https://doi.org/10.1016/j.jad.2023.04.044
https://doi.org/10.1016/j.jad.2023.04.044
Autor:
Caitlin A, Madison, Roanna A, Debler, Nathan I, Vardeleon, Lauren, Hillbrick, Arul, Jayaraman, Stephen, Safe, Robert S, Chapkin, Shoshana, Eitan
Publikováno v:
Journal of Affective Disorders. 319:213-220
Our recent study demonstrated that selective aryl hydrocarbon receptor modulators (SAhRMs), such as 1,4-dihydroxy-2-napthoic acid (DHNA) act as antidepressants in female mice. Given that some effects of certain SAhRMs are known to also be mediated vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec61d6eaf79d71817a4563a9866047a2
https://doi.org/10.1016/j.jad.2022.09.155
https://doi.org/10.1016/j.jad.2022.09.155
Autor:
Caitlin A. Madison, Jacob Kuempel, Georgia Lee Albrecht, Lauren Hillbrick, Arul Jayaraman, Stephen Safe, Robert S. Chapkin, Shoshana Eitan
Publikováno v:
J Affect Disord
BACKGROUND: Current pharmaceutical treatments for depression are sometimes ineffective and may have unwanted side effects that interfere with patient compliance. This study examined the potential antidepressant-like effects of dietary- and microbial-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2fb2bea5120e0bdc74daf9ef807fe0c
https://doi.org/10.1016/j.jad.2022.04.106
https://doi.org/10.1016/j.jad.2022.04.106
Publikováno v:
Neuroscience & Biobehavioral Reviews. 127:284-295
Opioids are highly efficacious in their ability to relieve pain, but they are liable for abuse, dependence, and addiction. Risk factors to develop opioid use disorders (OUD) include chronic stress, socio-environment, and preexisting major depressive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3d543e04e05a1ab01f56e78d17fe25
https://doi.org/10.1016/j.neubiorev.2021.04.019
https://doi.org/10.1016/j.neubiorev.2021.04.019
Autor:
Caitlin A. Madison, Lauren Hillbrick, Jacob Kuempel, Georgia Lee Albrecht, Kerstin K. Landrock, Stephen Safe, Robert S. Chapkin, Shoshana Eitan
Publikováno v:
Behavioural brain research. 440
The aryl hydrocarbon receptor (AhR) is a key regulator in the microbiome-gut-brain axis, and AhR-active microbial metabolites modulate multiple neuronal responses. We recently demonstrated that 3,3'-diindolylmethane (DIM) and 1,4-dihydroxy-2-naphthoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b8293197242818586a3ce86929befa
https://pubmed.ncbi.nlm.nih.gov/36528169
https://pubmed.ncbi.nlm.nih.gov/36528169
Publikováno v:
Journal of Psychopharmacology. 34:771-777
Background: Opioids are commonly prescribed to treat moderate-to-severe pain. However, their use can trigger the development of opioid use disorder. A major problem in treating opioid use disorder remains the high rate of relapse. Aim: The purpose of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24349f89393a8d92fb91618a94fa7604
https://doi.org/10.1177/0269881120926675
https://doi.org/10.1177/0269881120926675
Publikováno v:
ACS Chemical Neuroscience. 11:1955-1964
Chronic use of opioids can lead to tolerance, dependence, abuse, and addiction. This in turn can result in dose escalation and opioid overdose. Opioid overdose can be fatal due to severe opioid-induced respiratory depression (OIRD). Naloxone, a nonsp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8891b75f760cfa3e62317b0ac9569bf0
https://doi.org/10.1021/acschemneuro.0c00141
https://doi.org/10.1021/acschemneuro.0c00141
Publikováno v:
Behavioural Pharmacology. 31:293-307
Social environment influences the trajectory of developing opioid use disorder (OUD). Thus, the present study tested the hypothesis that sociability levels will affect the responses to opioids. Mice were tested for their baseline sociability, anxiety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5d1138cfd8d6c236ec4b7f5b69f155
https://doi.org/10.1097/fbp.0000000000000552
https://doi.org/10.1097/fbp.0000000000000552
Autor:
Shoshana Eitan, Caitlin A Madison
Publikováno v:
Psychological medicine. 50(6)
BackgroundDepression and post-traumatic stress disorder (PTSD) are leading causes of disability and loss of life by suicide. Currently, there are less than satisfactory medical solutions to treat these mental disorders. Here, we explore recent precli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e2b28310378fe49faaf4703c9b11ef
https://pubmed.ncbi.nlm.nih.gov/32204739
https://pubmed.ncbi.nlm.nih.gov/32204739
Publikováno v:
Drug and Alcohol Dependence. 188:113-118
Background The association with opioid-abusing individuals or even the perception of opioid abuse by peers are risk factors for the initiation and escalation of abuse. Similarly, we demonstrated that morphine-treated animals housed with only morphine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9cf01f9e421d1669c91e118361c90d
https://doi.org/10.1016/j.drugalcdep.2018.03.021
https://doi.org/10.1016/j.drugalcdep.2018.03.021