Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Shortnacy-Fowler AT"'
Autor:
Tiwari, KamalN.1 (AUTHOR), Shortnacy-Fowler, AnitaT.1 (AUTHOR), Parker, WilliamB.1 (AUTHOR), Waud, WilliamR.1 (AUTHOR), Secrist III, JohnA.1 (AUTHOR) Secrist@sri.org
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. May2009, Vol. 28 Issue 5-7, p657-677. 21p. 2 Diagrams, 2 Charts, 1 Graph.
Autor:
Shortnacy-Fowler, AnitaT.1 (AUTHOR), Tiwari, KamalN.1 (AUTHOR), Montgomery, JohnA.1 (AUTHOR), Secrist III, JohnA.1 (AUTHOR)
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. Aug2001, Vol. 20 Issue 8, p1583-1598. 16p.
Autor:
William R. Waud, John A. Secrist, William B. Parker, Kamal N. Tiwari, Anita T. Shortnacy-Fowler
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 28:657-677
As part of an ongoing program to develop novel antitumor agents over the years, we have synthesized and evaluated a number of 4'-C-substituted nucleosides. A few years ago, we reported the first synthesis of 4'-C-hydroxymethyl-2'-fluoro arabino nucle
Autor:
William B. Parker, Loredana Cappellacci, Kamal N. Tiwari, William R. Waud, John A. Secrist, Anita T. Shortnacy-Fowler, John A. Montgomery
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 19:2005-2017
Four 5-substituted (chloro, fluoro, bromo, methyl) 1-(4-thio-beta-D-arabinofuranosyl)cytosines and their alpha anomers were synthesized by a facile route in high yields. All of these nucleosides were evaluated for cytotoxicity against a panel of huma
Autor:
William B. Parker, John A. Secrist, Kamal N. Tiwari, Loredana Cappellacci, John A. Montgomery, William R. Waud, Anita T. Shortnacy-Fowler
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 19:329-340
4'-thio-beta-D-arabinofuranosylcytosine was synthesized by a facile route in high yields. It was evaluated for antitumor activity against a panel of human tumors, both in vitro and in vivo.
Autor:
Kamal N. Tiwari, John A. Secrist, Robert W. Buckheit, John A. Montgomery, Anita T. Shortnacy-Fowler, Frank Seela
Publikováno v:
Helvetica Chimica Acta. 82:2240-2245
Coupling of 2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide with 4-methoxypyrazolo[3,4-d]pyrimidine gave an α-D/β-D mixture of N1- and N2-coupled products. All the anomers were separated and deblocked to yield the corresponding nucleosides.
Autor:
John A. Montgomery, Kamal N. Tiwari, Anita T. Shortnacy-Fowler, Lea Messini, John A. Secrist, James M. Riordan, Scott C. Meyers, Steven E. Ealick
Publikováno v:
Journal of Medicinal Chemistry. 41:3865-3871
A series of 4'-thio-D-arabinofuranosylpurine nucleosides was prepared and evaluated as potential anticancer agents. The details of a convenient and high-yielding synthesis of the carbohydrate precursor 1-O-acetyl-2,3,5-tri-O-benzyl-4-thio-D-arabinofu
Autor:
Charles A. Krauth, Anita T. Shortnacy-Fowler, John A. Secrist, G. Arnett, John A. Montgomery, Cecil D. Kwong, William M. Shannon, Melinda G. Hollingshead
Publikováno v:
Nucleosides and Nucleotides. 17:1409-1443
The activity of a series of compounds related to adenosine-N 1-oxide (1) and 1-(benzyloxy)adenosine (42) against vaccinia virus has been determined both in vitro and in a vaccinia mouse tailpox model. Significant activities have been found both in vi
Publikováno v:
Nucleosides and Nucleotides. 13:1017-1029
A series of 8-substituted purine ribonucleosides were prepared from 2′, 3′, 5′-tri-O-acetyl-8-bromoadenosine and evaluated for cytotoxicity and antiviral activity. Four of these nucleosides (6b-9b) were significantly toxic to both HEp-2 and L12
Publikováno v:
ChemInform. 26