Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Short-read sequencing"'
Autor:
Kristen J. Wade, Rayo Suseno, Kerry Kizer, Jacqueline Williams, Juliano Boquett, Stacy Caillier, Nicholas R. Pollock, Adam Renschen, Adam Santaniello, Jorge R. Oksenberg, Paul J. Norman, Danillo G. Augusto, Jill A. Hollenbach
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-23 (2024)
Abstract The extremely high levels of genetic polymorphism within the human major histocompatibility complex (MHC) limit the usefulness of reference-based alignment methods for sequence assembly. We incorporate a short-read, de novo assembly algorith
Externí odkaz:
https://doaj.org/article/da420c82ac434ddc86e06bc9431d32c9
Autor:
Dora M. Rajonhson, Pacharaporn Angthong, Timpika Thepsuwan, Sawannee Sutheeworapong, Penpicha Satanwat, Paveena Tapaneeyaworawong, Sorawit Powtongsook, Worarat Kruasuwan, Piroon Jenjaroenpun, Thidathip Wongsurawat, Sage Chaiyapechara, Wanilada Rungrassamee
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT Despite their immense economic value as a key aquaculture species, the production of Pacific white shrimp (Litopenaeus vannamei) faces significant challenges from intensive farming practices and disease outbreaks. Routine microbial profiling
Externí odkaz:
https://doaj.org/article/69cd3724ae5048bf8115388d342ea95f
Autor:
Lauge Holm Sørensen, Susanne Karlsmose Pedersen, Jacob Dyring Jensen, Niamh Lacy-Roberts, Athina Andrea, Michael S. M. Brouwer, Kees T. Veldman, Yan Lou, Maria Hoffmann, Rene S. Hendriksen
Publikováno v:
mSystems, Vol 9, Iss 9 (2024)
ABSTRACT As antimicrobial resistance (AMR) surveillance shifts to genomics, ensuring the quality of whole-genome sequencing (WGS) data produced across laboratories is critical. Participation in genomic proficiency tests (GPTs) not only increases indi
Externí odkaz:
https://doaj.org/article/ac0fb612ce65470aaed0fa33bfc40c09
Autor:
Isaac Framst, Rebecca M. Wolking, Justin Schonfeld, Nicole Ricker, Janet Beeler-Marfisi, Gabhan Chalmers, Pauline L. Kamath, Grazieli Maboni
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionSpillover events of Mycoplasma ovipneumoniae have devastating effects on the wild sheep populations. Multilocus sequence typing (MLST) is used to monitor spillover events and the spread of M. ovipneumoniae between the sheep populations. M
Externí odkaz:
https://doaj.org/article/0d3b8a1d893a41399cc562193b7c9a10
Autor:
Kasimsetty, Aradhana 1, Hwang, Young 1, Everett, John K. 1, McFarland, Alexander G. 1, Zolnoski, Sonja A. 1, Lu, Tianyu 1, Roche, Aoife M. 1, Martínez-García, Pedro Manuel 4, Sabatino, Denise E. 2, 3, Bushman, Frederic D. 1, ∗
Publikováno v:
In Molecular Therapy - Methods & Clinical Development 12 December 2024 32(4)
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/0bf68de1d6bd4bb78b0723e95b765380
Autor:
Guilherme B. Neumann, Paula Korkuć, Monika Reißmann, Manuel J. Wolf, Katharina May, Sven König, Gudrun A. Brockmann
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-7 (2023)
Abstract When resequencing animal genomes, some short reads cannot be mapped to the reference genome and are usually discarded. In this study, unmapped reads from 302 German Black Pied cattle were analyzed to identify potential pathogenic DNA. These
Externí odkaz:
https://doaj.org/article/708b00d4dd314b00b180daccf0b38d19
Autor:
Niamh M. Ryan, Aiden Corvin
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-11 (2023)
Abstract The human genome contains regions that cannot be adequately assembled or aligned using next generation short-read sequencing technologies. More than 2500 genes are known contain such ‘dark’ regions. In this study, we investigate the nega
Externí odkaz:
https://doaj.org/article/afee534b54f84988a488977764c9177e
Autor:
Laurie Lecomte, Mariann Árnyasi, Anne‐Laure Ferchaud, Matthew Kent, Sigbjørn Lien, Kristina Stenløkk, Florent Sylvestre, Louis Bernatchez, Claire Mérot
Publikováno v:
Evolutionary Applications, Vol 17, Iss 3, Pp n/a-n/a (2024)
Abstract Genomic structural variants (SVs) are now recognized as an integral component of intraspecific polymorphism and are known to contribute to evolutionary processes in various organisms. However, they are inherently difficult to detect and geno
Externí odkaz:
https://doaj.org/article/af2bf1f321854600af8440ea2f99cf5d
Autor:
Tatiana Maroilley, Meng‐Han Tsai, Rumika Mascarenhas, Catherine Diao, Maryam Khanbabaei, Sabine Kaya, Christel Depienne, Maja Tarailo‐Graovac, Karl Martin Klein
Publikováno v:
Epilepsia Open, Vol 8, Iss 2, Pp 659-665 (2023)
Abstract Familial adult myoclonic epilepsy (FAME) is an adult‐onset neurological disease characterized by cortical tremor, myoclonus, and seizures due to a pentanucleotide repeat expansion: a combination of pathogenic TTTCA expansion associated wit
Externí odkaz:
https://doaj.org/article/b2e5a45fd1074c5ebc0bbf673f737af7