Zobrazeno 1 - 10
of 1 173
pro vyhledávání: '"Short read"'
Publikováno v:
Genomics & Informatics, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Rapidly increasing the amount of short-read data generated by NGSs (new-generation sequencers) calls for the development of fast and accurate read alignment programs. The programs based on the hash table (BLAST) and Burrows-Wheeler transform
Externí odkaz:
https://doaj.org/article/bc2b53d30bf04e8d835215d9a284c30e
Autor:
Kristen J. Wade, Rayo Suseno, Kerry Kizer, Jacqueline Williams, Juliano Boquett, Stacy Caillier, Nicholas R. Pollock, Adam Renschen, Adam Santaniello, Jorge R. Oksenberg, Paul J. Norman, Danillo G. Augusto, Jill A. Hollenbach
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-23 (2024)
Abstract The extremely high levels of genetic polymorphism within the human major histocompatibility complex (MHC) limit the usefulness of reference-based alignment methods for sequence assembly. We incorporate a short-read, de novo assembly algorith
Externí odkaz:
https://doaj.org/article/da420c82ac434ddc86e06bc9431d32c9
Autor:
Signe Bråtelund, Tom Ruttink, Franz Goecke, Ole Jacob Broch, Gunnar Klemetsdal, Jørgen Ødegård, Åshild Ergon
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-22 (2024)
Abstract Background Kelps are not only ecologically important, being primary producers and habitat forming species, they also hold substantial economic potential. Expansion of the kelp cultivation industry raises the interest for genetic improvement
Externí odkaz:
https://doaj.org/article/a61c38eb84ca46f9ab9047882b76a4de
Autor:
Dora M. Rajonhson, Pacharaporn Angthong, Timpika Thepsuwan, Sawannee Sutheeworapong, Penpicha Satanwat, Paveena Tapaneeyaworawong, Sorawit Powtongsook, Worarat Kruasuwan, Piroon Jenjaroenpun, Thidathip Wongsurawat, Sage Chaiyapechara, Wanilada Rungrassamee
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT Despite their immense economic value as a key aquaculture species, the production of Pacific white shrimp (Litopenaeus vannamei) faces significant challenges from intensive farming practices and disease outbreaks. Routine microbial profiling
Externí odkaz:
https://doaj.org/article/69cd3724ae5048bf8115388d342ea95f
Autor:
Lauge Holm Sørensen, Susanne Karlsmose Pedersen, Jacob Dyring Jensen, Niamh Lacy-Roberts, Athina Andrea, Michael S. M. Brouwer, Kees T. Veldman, Yan Lou, Maria Hoffmann, Rene S. Hendriksen
Publikováno v:
mSystems, Vol 9, Iss 9 (2024)
ABSTRACT As antimicrobial resistance (AMR) surveillance shifts to genomics, ensuring the quality of whole-genome sequencing (WGS) data produced across laboratories is critical. Participation in genomic proficiency tests (GPTs) not only increases indi
Externí odkaz:
https://doaj.org/article/ac0fb612ce65470aaed0fa33bfc40c09
Autor:
Isaac Framst, Rebecca M. Wolking, Justin Schonfeld, Nicole Ricker, Janet Beeler-Marfisi, Gabhan Chalmers, Pauline L. Kamath, Grazieli Maboni
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionSpillover events of Mycoplasma ovipneumoniae have devastating effects on the wild sheep populations. Multilocus sequence typing (MLST) is used to monitor spillover events and the spread of M. ovipneumoniae between the sheep populations. M
Externí odkaz:
https://doaj.org/article/0d3b8a1d893a41399cc562193b7c9a10
Publikováno v:
PeerJ, Vol 12, p e17748 (2024)
Background Tandem duplication (TD) is a common and important type of structural variation in the human genome. TDs have been shown to play an essential role in many diseases, including cancer. However, it is difficult to accurately detect TDs due to
Externí odkaz:
https://doaj.org/article/647c96dccc2b4c7c80fb4d7e8ba93ee3
Autor:
Nikolett Szakállas, Barbara K. Barták, Gábor Valcz, Zsófia B. Nagy, István Takács, Béla Molnár
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
The large-scale heterogeneity of genetic diseases necessitated the deeper examination of nucleotide sequence alterations enhancing the discovery of new targeted drug attack points. The appearance of new sequencing techniques was essential to get more
Externí odkaz:
https://doaj.org/article/881364eb0fd04ce2abc71adbb856ef8d
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/0bf68de1d6bd4bb78b0723e95b765380
Autor:
Laurie Lecomte, Mariann Árnyasi, Anne‐Laure Ferchaud, Matthew Kent, Sigbjørn Lien, Kristina Stenløkk, Florent Sylvestre, Louis Bernatchez, Claire Mérot
Publikováno v:
Evolutionary Applications, Vol 17, Iss 3, Pp n/a-n/a (2024)
Abstract Genomic structural variants (SVs) are now recognized as an integral component of intraspecific polymorphism and are known to contribute to evolutionary processes in various organisms. However, they are inherently difficult to detect and geno
Externí odkaz:
https://doaj.org/article/af2bf1f321854600af8440ea2f99cf5d