Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shorena Gelozia"'
Autor:
Monica X. Li, Shorena Gelozia, Gaddafi I. Danmaliki, Yurong Wen, Philip B. Liu, M. Joanne Lemieux, Frederick G. West, Brian D. Sykes, Peter M. Hwang
Publikováno v:
Biochemistry and Biophysics Reports, Vol 16, Iss , Pp 145-151 (2018)
The compound MCI-154 was previously shown to increase the calcium sensitivity of cardiac muscle contraction. Using solution NMR spectroscopy, we demonstrate that MCI-154 interacts with the calcium-sensing subunit of the cardiac troponin complex, card
Externí odkaz:
https://doaj.org/article/7921eb263864415793b07715535b4a6d
Publikováno v:
Chemistry - A European Journal. 24:6052-6056
Organoaluminum-mediated double interrupted Nazarov cyclization to access bicyclo[3.1.0]hexanols via nucleophilic methyl attack followed by Simmons-Smith-type electrophilic cyclopropanation is reported. These alcohols can undergo ring opening to affor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9291c26c1abb62843157d77b727454d5
https://doi.org/10.1002/chem.201800758
https://doi.org/10.1002/chem.201800758
Autor:
Peter M. Hwang, Fangze Cai, Frederick G. West, Steffen Lindert, Shorena Gelozia, Sandra E. Pineda-Sanabria, Monica X. Li, Brian D. Sykes
Publikováno v:
Journal of Molecular and Cellular Cardiology. 101:134-144
In cardiac and skeletal muscle, the troponin complex turns muscle contraction on and off in a calcium-dependent manner. Many small molecules are known to bind to the troponin complex to modulate its calcium binding affinity, and this may be useful in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad2f1487eb989d94759d99c5c6dbaa7a
https://doi.org/10.1016/j.yjmcc.2016.10.016
https://doi.org/10.1016/j.yjmcc.2016.10.016
Autor:
Peter M. Hwang, Shorena Gelozia, Gaddafi I. Danmaliki, Frederick G. West, Monica X. Li, Brian D. Sykes, Yurong Wen, Philip B. Liu, M. Joanne Lemieux
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 16, Iss, Pp 145-151 (2018)
Biochemistry and Biophysics Reports, Vol 16, Iss, Pp 145-151 (2018)
The compound MCI-154 was previously shown to increase the calcium sensitivity of cardiac muscle contraction. Using solution NMR spectroscopy, we demonstrate that MCI-154 interacts with the calcium-sensing subunit of the cardiac troponin complex, card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01770d43974b586a21b4f6ffb374fa11
https://pubmed.ncbi.nlm.nih.gov/30417133
https://pubmed.ncbi.nlm.nih.gov/30417133
Autor:
J. Andrew McCammon, Sandra E. Pineda-Sanabria, Brian D. Sykes, Peter M. Hwang, Steffen Lindert, Fangze Cai, Shorena Gelozia, Monica Li, Frederick G. West
Publikováno v:
Biophysical Journal. 110(3)
Heart failure is the end stage of almost all heart disease, characterized by an inability of the heart to pump enough blood to satisfy the needs of the body. Systolic heart failure is caused by impaired cardiac muscle contraction. In theory, an ideal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995ba1c2365a440b3a774d8d658a7ad0
Publikováno v:
Journal of Enzyme Inhibition & Medicinal Chemistry. 2022, Vol. 37 Issue 1, p641-651. 11p.
Autor:
Gelozia, Shorena1, Kwon, Yonghoon1, McDonald, Robert1, West, F. G.1 frederick.west@ualberta.ca
Publikováno v:
Chemistry - A European Journal. 4/20/2018, Vol. 24 Issue 23, p6052-6056. 5p.