Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Shontelle Dodson"'
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Muscle Wasting in Cancer Cachexia: Clinical Implications, Diagnosis, and Emerging Treatment Strategies
Autor: Mitchell S. Steiner, David Cella, Vickie E. Baracos, Aminah Jatoi, William J. Evans, James T. Dalton, Shontelle Dodson
Publikováno v: Annual Review of Medicine. 62:265-279
Cancer cachexia is a complex metabolic condition characterized by loss of skeletal muscle. Common clinical manifestations include muscle wasting, anemia, reduced caloric intake, and altered immune function, which contribute to increased disability, f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671814b5911ffaea1ca6460c92e02d9d
https://doi.org/10.1146/annurev-med-061509-131248
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Effect of enobosarm on physical function in cancer patients with < or ≥ 5% weight loss in a phase IIb trial
Autor: Mary Ann Johnston, Mitchell S. Steiner, Michael L. Hancock, Shontelle Dodson
Publikováno v: Journal of Clinical Oncology. 30:e19585-e19585
e19585 Background: Although cachexia has been defined as >5% weight loss, limited data exists on the prevention and treatment of muscle wasting prior to a patient becoming cachectic. Cancer induced muscle wasting can begin early in the course of a pa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d7861a97bddb1337651b611cb6eb50b
https://doi.org/10.1200/jco.2012.30.15_suppl.e19585
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6
Prevalence and impact of hypogonadism in cancer patients with severe muscle wasting in phase IIb enobosarm trial
Autor: Mary Ann Johnston, Adrian S. Dobs, Mitchell S. Steiner, Ronald A. Morton, Shontelle Dodson, Michael L. Hancock
Publikováno v: Journal of Clinical Oncology. 30:e19582-e19582
e19582 Background: Hypogonadism has been associated with weight loss and poor outcomes in cancer patients. Up to 50% of males with advanced cancer are hypogonadal at presentation or during the course of treatment. Wasting in cancer patients has also
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7175442a01d88950963aa2761493c839
https://doi.org/10.1200/jco.2012.30.15_suppl.e19582
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The impact of less than 8% weight loss on overall survival in subjects with non-small cell lung cancer (NSCLC) treated in a phase IIb trial of GTx-024
Autor: Michael L. Hancock, Adrian S. Dobs, Mitchell S. Steiner, Mary Ann Johnston, Shontelle Dodson
Publikováno v: Journal of Clinical Oncology. 29:9117-9117
9117 Background: Cancer cachexia causes muscle wasting and decline in physical function. Studies show that NSCLC patients with weight loss at diagnosis have worse treatment outcomes and shorter ove...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e36d07851d0a0fa42af5fc687f965dc0
https://doi.org/10.1200/jco.2011.29.15_suppl.9117
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Effect of GTx-024, a selective androgen receptor modulator (SARM), on physical function in patients with non-small cell lung cancer (NSCLC) with cancer cachexia
Autor: G. Barnette, Mitchell S. Steiner, Shontelle Dodson, Mary Ann Johnston, Adrian S. Dobs, Michael L. Hancock
Publikováno v: Journal of Clinical Oncology. 29:9022-9022
9022 Background: Cancer cachexia causes muscle wasting and leads to decline in physical function. NSCLC patients with weight loss at diagnosis are less able to tolerate chemotherapy, have worse out...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17019aeb214767fd95ba12144352a033
https://doi.org/10.1200/jco.2011.29.15_suppl.9022
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9
Effect of GTx-024, a selective androgen receptor modulator (SARM), on stair climb performance and quality of life (QOL) in patients with cancer cachexia
Autor: K.G. Barnette, Michael L. Hancock, Shontelle Dodson, Mitchell S. Steiner, D. Rodriguez, Ronald A. Morton
Publikováno v: Journal of Clinical Oncology. 28:9147-9147
9147 Background: Cancer cachexia is a catabolic muscle wasting condition that leads to a reduction in lean body mass (LBM). The associated changes not only affect patient's health, but also QOL. We...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::43da57c79099c40eeb1fbf0f7b17e8f0
https://doi.org/10.1200/jco.2010.28.15_suppl.9147
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The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial
Autor: Mitchell S. Steiner, James T. Dalton, Shontelle Dodson, Kester G. Barnette, Michael L. Hancock, Casey E. Bohl, D. Rodriguez, Ronald A. Morton
Publikováno v: Journal of Cachexia, Sarcopenia and Muscle
BACKGROUND: Cachexia, also known as muscle wasting, is a complex metabolic condition characterized by loss of skeletal muscle and a decline in physical function. Muscle wasting is associated with cancer, sarcopenia, chronic obstructive pulmonary dise
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad4b13bc3bd9233eb68da47d2d026b2
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