Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Shonna Kaye Fleck"'
Autor:
Glen R. Nemerow, Susan C. Stevenson, Shonna Kaye Fleck, Edith Aguilar, Dan J. Von Seggern, J.C Gonzalez Armas, Martin Friedlander, Karen Kinder, Peter Ghazal
Publikováno v:
Molecular Therapy. 7:27-34
Strategies for retargeting adenoviral (Ad) vectors have been developed, but their in vivo efficacy remains to be demonstrated. Gene delivery to specific ocular cell types represents an approach to treating many diseases that cause irreversible blindn
Publikováno v:
Journal of Virology. 73:1601-1608
Adenoviruses (Ads) are nonenveloped DNA viruses with icosahedral symmetry. There are at least 47 known Ad serotypes, many of which are associated with respiratory, gastrointestinal, or ocular disease (23). Ad has served as a model for the study of ma
Autor:
Joan Fernandez, Glen R. Nemerow, Shonna Kaye Fleck, Eugene Wu, Shuang Huang, Dan J. Von Seggern
Publikováno v:
Virology. 279(1)
The ocular tropism of adenovirus type 37 (Ad37) does not correlate with the wide distribution of the 46-kDa coxsackievirus and adenovirus receptor (CAR), the major receptor for most adenovirus serotypes. We previously found that Ad37 infects and bind
Publikováno v:
Journal of virology. 74(1)
While adenovirus (Ad) gene delivery vectors are useful in many gene therapy applications, their broad tropism means that they cannot be directed to a specific target cell. There are also a number of cell types involved in human disease which are not