Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Shoma Tsubota"'
Autor:
Hiroki Kitai, Noritoshi Kato, Koichi Ogami, Shintaro Komatsu, Yu Watanabe, Seiko Yoshino, Eri Koshi, Shoma Tsubota, Yoshio Funahashi, Takahiro Maeda, Kazuhiro Furuhashi, Takuji Ishimoto, Tomoki Kosugi, Shoichi Maruyama, Kenji Kadomatsu, Hiroshi I. Suzuki
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-23 (2022)
Abstract Background Combinatorial gene regulation by multiple microRNAs (miRNAs) is widespread and closely spaced target sites often act cooperatively to achieve stronger repression (“neighborhood” miRNA cotargeting). While miRNA cotarget sites a
Externí odkaz:
https://doaj.org/article/814489ea1fa84422a7415f8368b0e8b0
Autor:
Lei Zhai, Anushree Balachandran, Rebecca Larkin, Janith A. Seneviratne, Sylvia A. Chung, Amit Lalwani, Shoma Tsubota, Dominik Beck, Kenji Kadomatsu, Anneleen Beckers, Kaat Durink, Katleen De Preter, Frank Speleman, Michelle Haber, Murray D. Norris, Alexander Swarbrick, Belamy B. Cheung, Glenn M. Marshall, Daniel R. Carter
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15571 (2023)
MYCN amplification occurs in approximately 20–30% of neuroblastoma patients and correlates with poor prognosis. The TH-MYCN transgenic mouse model mimics the development of human high-risk neuroblastoma and provides strong evidence for the oncogeni
Externí odkaz:
https://doaj.org/article/d559d7b12c324b4bb5d46cc7f02c2a1c
Autor:
Akihiro Ryuge, Tomoki Kosugi, Kayaho Maeda, Ryoichi Banno, Yang Gou, Kei Zaitsu, Takanori Ito, Yuka Sato, Akiyoshi Hirayama, Shoma Tsubota, Takashi Honda, Kazuki Nakajima, Tomoya Ozaki, Kunio Kondoh, Kazuo Takahashi, Noritoshi Kato, Takuji Ishimoto, Tomoyoshi Soga, Takahiko Nakagawa, Teruhiko Koike, Hiroshi Arima, Yukio Yuzawa, Yasuhiko Minokoshi, Shoichi Maruyama, Kenji Kadomatsu
Publikováno v:
JCI Insight, Vol 6, Iss 20 (2021)
Monocarboxylates, such as lactate and pyruvate, are precursors for biosynthetic pathways, including those for glucose, lipids, and amino acids via the tricarboxylic acid (TCA) cycle and adjacent metabolic networks. The transportation of monocarboxyla
Externí odkaz:
https://doaj.org/article/2d5d18e46a2a402ab5dd1a6ba411562d
Autor:
Motoharu Hamada, Nobuhiro Nishio, Yusuke Okuno, Satoshi Suzuki, Nozomu Kawashima, Hideki Muramatsu, Shoma Tsubota, Matthew H. Wilson, Daisuke Morita, Shinsuke Kataoka, Daisuke Ichikawa, Norihiro Murakami, Rieko Taniguchi, Kyogo Suzuki, Daiei Kojima, Yuko Sekiya, Eri Nishikawa, Atsushi Narita, Asahito Hama, Seiji Kojima, Yozo Nakazawa, Yoshiyuki Takahashi
Publikováno v:
EBioMedicine, Vol 34, Iss , Pp 18-26 (2018)
Insertional mutagenesis is an important risk with all genetically modified cell therapies, including chimeric antigen receptor (CAR)-T cell therapy used for hematological malignancies. Here we describe a new tagmentation-assisted PCR (tag-PCR) system
Externí odkaz:
https://doaj.org/article/1c1f19432a8a44f499fd2f54a51c2412
Autor:
Dongliang Cao, Satoshi Kishida, Peng Huang, Ping Mu, Shoma Tsubota, Masaaki Mizuno, Kenji Kadomatsu
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86813 (2014)
Tumorsphere culture enriches and expands tumor cells, thus providing important resources for cancer studies. However, as compared with metastatic tissues, primary tumors in the nervous system rarely give rise to long-surviving tumorspheres, thereby s
Externí odkaz:
https://doaj.org/article/b447d872521a4946bc4b64ad17be890a
Autor:
Kenji Kadomatsu, Toshikazu Ushijima, Shinichi Kiyonari, Dongliang Cao, Satoshi Yamashita, Miki Ohira, Teppei Shimamura, Satoshi Kishida, Shoma Tsubota
This file contains additional details of materials and methods used in this study including medium preparation, H&E staining, immunofluorescence analysis of frozen sections, immunohistochemistry on paraffin sections, in situ hybridization, western bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dab1ae55f53f158de01948365849384
https://doi.org/10.1158/0008-5472.22414214.v1
https://doi.org/10.1158/0008-5472.22414214.v1
Autor:
Kenji Kadomatsu, Toshikazu Ushijima, Shinichi Kiyonari, Dongliang Cao, Satoshi Yamashita, Miki Ohira, Teppei Shimamura, Satoshi Kishida, Shoma Tsubota
This file contains Supplementary Fig. S1 to S8. Figure S1: RA (+) and RA (-) medium comparison. Figure S2: Transcriptomic differences in SMG and spheres from 3-week-old WT and TH-MYCN mice. Figure S3: Expression pattern of human MYCN mRNA and H&E sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d91d5eee140da46c7fe4d31035c2d5
https://doi.org/10.1158/0008-5472.22414217
https://doi.org/10.1158/0008-5472.22414217
Autor:
Kenji Kadomatsu, Toshikazu Ushijima, Shinichi Kiyonari, Dongliang Cao, Satoshi Yamashita, Miki Ohira, Teppei Shimamura, Satoshi Kishida, Shoma Tsubota
A microarray analysis among 3-week-old WT SMG, TH-MYCN SMG, and TH-MYCN spheres. The table contains data processing, probe information, and the list of genes in three groups, and the results of gene ontology analysis for each group.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec0e5380030dea31e2cc8929d144130
https://doi.org/10.1158/0008-5472.22414229.v1
https://doi.org/10.1158/0008-5472.22414229.v1
Autor:
Kenji Kadomatsu, Toshikazu Ushijima, Shinichi Kiyonari, Dongliang Cao, Satoshi Yamashita, Miki Ohira, Teppei Shimamura, Satoshi Kishida, Shoma Tsubota
The table contains the list of PRC2 target genes created by Ben-Porath et al., and the result of microarray analysis for PRC2 components between E13.5 TH-MYCN spheres and E13.5 WT spheres.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4236e9a48759206ea6b1b0803c7269f6
https://doi.org/10.1158/0008-5472.22414211.v1
https://doi.org/10.1158/0008-5472.22414211.v1
Autor:
Kenji Kadomatsu, Toshikazu Ushijima, Shinichi Kiyonari, Dongliang Cao, Satoshi Yamashita, Miki Ohira, Teppei Shimamura, Satoshi Kishida, Shoma Tsubota
A microarray analysis of TH-MYCN spheres cultured in RA (+) and (-) medium. The table contains data processing, probe information, and the results of gene ontology analysis for differentially expressed genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e4433018ffe7c9a63e29cf16d04601
https://doi.org/10.1158/0008-5472.22414223.v1
https://doi.org/10.1158/0008-5472.22414223.v1