Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shokoufeh Ghezelbash"'
Publikováno v:
Journal of Cardiovascular Pharmacology, 66(6), 515-522. LIPPINCOTT WILLIAMS & WILKINS
Atrial fibrillation (AF) is the most common cardiac arrhythmia with a substantial impact on morbidity and mortality. Antiarrhythmic drugs play a major role in rhythm-control therapy of AF. However, currently available agents exhibit limited efficacy
Autor:
Issam Abu-Taha, Scott A. LeMaire, Luge Li, Katherina M. Alsina, Larry D. Scott, Prince Jeyabal, Dobromir Dobrev, Shuyi Cao, Corey L. Reynolds, Ying H. Shen, Shokoufeh Ghezelbash, Ali El-Armouche, Xander H.T. Wehrens, Gong Chen, Xiaolu Pan, Tina Veleva, Christine Beeton, Stanley Nattel, Chunxia Yao, Wilhelm Schmitz, N. Tony Eissa, Frank U. Müller, Na Li
Publikováno v:
Circulation. 138(20)
Background: Atrial fibrillation (AF) is frequently associated with enhanced inflammatory response. The NLRP3 (NACHT, LRR, and PYD domain containing protein 3) inflammasome mediates caspase-1 activation and interleukin-1β release in immune cells but
Autor:
Dobromir Dobrev, Shokoufeh Ghezelbash
Publikováno v:
CardioVasc. 15:36-40
Es wird angenommen, dass Vorhofflimmern durch zwei Grundmechanismen entsteht: ektope (getriggerte) Aktivitat und kreisende Erregungen. Das Auslosen und Aufrechterhalten von Vorhofflimmern ist auf elektrophysiologische und strukturelle Veranderungen z
Publikováno v:
Journal of Molecular and Cellular Cardiology, 103, 110-120. ELSEVIER SCI LTD
Serine/threonine protein phosphatases control dephosphorylation of numerous cardiac proteins, including a variety of ion channels and calcium-handling proteins, thereby providing precise post-translational regulation of cardiac electrophysiology and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc352b5f397ff24c484b2af7d2045a6b
https://cris.maastrichtuniversity.nl/en/publications/003d5dfc-a83a-4be1-993a-0bce878245ac
https://cris.maastrichtuniversity.nl/en/publications/003d5dfc-a83a-4be1-993a-0bce878245ac
Introduction: Although there have been important technological advances for the treatment of cardiac arrhythmias (e.g., catheter ablation technology), antiarrhythmic drugs (AADs) remain the cornerstone therapy for the majority of patients with arrhyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5d24c5119530c39fb0fc0fc313faab
https://www.ncbi.nlm.nih.gov/pubmed/28691539
https://www.ncbi.nlm.nih.gov/pubmed/28691539
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Atrial fibrillation (AF) is a complex disease process, and the molecular mechanisms underlying initiation and progression of the disease are unclear. Consequently, AF has been difficult to model. In this study, we have presented a novel tr
Autor:
Gerrit Frommeyer, Lars Eckardt, Sridharan Rajamani, Peter Milberg, Shokoufeh Ghezelbash, Nani Osada, Luiz Belardinelli, Radu Razvan, Günter Breithardt
Publikováno v:
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 15(5)
Aims In several clinical and pre-clinical studies, application of ranolazine (RAN) led to suppression of atrial fibrillation (AF). The aim of the present study was to investigate whether RAN can suppress AF in an experimental rabbit whole heart model
Autor:
Jordi Heijman, Dobromir Dobrev, Lina Badimon, Shokoufeh Ghezelbash, Niels Voigt, Cristina E. Molina
Publikováno v:
EP Europace. 17:iii88-iii88
557 Determinants of altered atrial Na+-Ca2+ exchanger function in patients with chronic atrial fibrillation {#article-title-2} Purpose: Dysfunctional Na+-Ca2+ exchanger type-1 (NCX1) is implicated in atrial fibrillation (AF) triggers/drivers, but the