Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Shoko Nagotani"'
Publikováno v:
Cell Transplantation, Vol 20 (2011)
Possible strategies for treating stroke include: 1) thrombolytic therapy with tissue plasminogen activator (tPA): restoring cerebral blood flow in the acute phase of ischemic stroke but sometimes causing hemorrhagic transformation (HT); 2) stem cell
Externí odkaz:
https://doaj.org/article/b9aff9f0a6be467c98cb8edfca5a8aad
Publikováno v:
Cell Transplantation, Vol 18 (2009)
Possible strategies for treating ischemic stroke include neuroprotection (preventing injured neurons from undergoing apoptosis in the acute phase of cerebral ischemia) and stem cell therapy (the repair of disrupted neuronal networks with newly born n
Externí odkaz:
https://doaj.org/article/04009af5973649b4b9760b3c9592e133
[Aseptic meningitis as paraneoplastic syndrome related to chronic myeloid leukemia in chronic phase]
Autor:
Yusuke, Meguri, Kentaro, Deguchi, Tomohito, Kawano, Kenta, Hayashino, Aya, Komura, Yutaro, Shiraishi, Chikamasa, Yoshida, Shoko, Nagotani, Kazuhiko, Yamamoto, Kenji, Imajo
Publikováno v:
[Rinsho ketsueki] The Japanese journal of clinical hematology. 62(11)
Chronic myeloid leukemia (CML) is a clonal hemopoietic stem cell disorder characterized by reciprocal translocation between the long arms of chromosomes 9 and 22 that produces the fusion BCR-ABL1 gene. Major manifestations in CML patients are increas
Autor:
Kenji, Yamazaki, Hiroshi, Wakabayashi, Yu, Suganami, Shinichi, Sano, Yu, Wakunami, Takashi, Katayama, Kentaro, Deguchi, Shoko, Nagotani, Masayuki, Kishida
Publikováno v:
Acta Medica Okayama. 71(4):341-344
We report a case of a woman with typical dermatomyositis (DM) with skin manifestations, severe myalgia and muscle weakness complicated by interstitial lung disease (ILD) and pneumomediastinum. Pneumomediastinum persisted despite treatment with immuno
Autor:
Atsushi Tsuchiya, Mikio Shoji, K. Abe, Han Zhe Zhang, Takeshi Hayashi, Kentaro Deguchi, Shoko Nagotani, Yoshihide Sehara, Xiquan Wang, Makiko Nagai
Publikováno v:
Neurological Research. 29:463-468
Platelet derived-endothelial cell growth factor (PD-ECGF) is a highly potent angiogenic factor. Although angiogenesis plays an active role in pathophysiology of stroke, the expression pattern of this molecule in ischemic brain has not been investigat
Autor:
Koji Abe, Shoko Nagotani, Makiko Nagai, Mikio Shoji, Takeshi Hayashi, Tatsushi Kamiya, Yasuyuki Ohta, Yasushi Takehisa, Nobuhiko Ohmori, Tetsuro Murakami, Isao Nagano, Miyuki Okamoto
Publikováno v:
Internal Medicine. 46:751-755
We report two patients with spinocerebellar ataxia (SCA) with cranial and spinal motor neuron involvement. They initially presented with cerebellar ataxia, followed by bulbar palsy and limb motor neuron sign. One of the patients had a brother with al
Autor:
Isao Nagano, Shoko Nagotani, Guang Jin, Kentaro Deguchi, Takeshi Hayashi, Hanzhe Zhang, Hiroshi Kamada, Yoshihide Sehara, Mikio Shoji, Koji Abe
Publikováno v:
Neurological Research. 28:822-825
Reduction of brain plasticity underlies the poor outcome of aged stroke patients. The molecular mechanism of plasticity reduction by aging is uncertain, but disturbed lipid metabolism may be implicated.We investigated the expression of low density li
Autor:
Guang Jin, Isao Nagano, Takeshi Hayashi, Feng Li, Mikio Shoji, Koji Abe, Pak H. Chan, Shoko Nagotani, Kentaro Deguchi
Publikováno v:
Brain Research. 1048:59-68
The endoplasmic reticulum (ER) plays an important role in ischemic neuronal cell death. In order to determine the effect of dantrolene, a ryanodine receptor antagonist, on ER stress response and ischemic brain injury, we investigated changes in ER st
Autor:
Isao Nagano, Mikio Shoji, Nam Ho Huh, Takeshi Hayashi, Masahiro Miyazaki, Mikiro Takaishi, Koji Abe, Shoko Nagotani, Atsuhiko Oohira, Guang Jin, Kentaro Deguchi, Feng Li
Publikováno v:
Brain Research. 1037:194-199
Neurocan is one of the major chondroitin sulfate proteoglycans in the nervous tissues. The expression and proteolytic cleavage of neurocan are developmentally regulated in the normal rat brain, and the full-length neurocan is detected in juvenile bra
Autor:
Kentaro Deguchi, Yoshihide Sehara, Isao Nagano, Takeshi Hayashi, Shoko Nagotani, Hanzhe Zhang, Mikio Shoji, Koji Abe, Tsuyomu Ikenoue, Masanori Iwai, Tomoaki Ikeda, Guang Jin
Publikováno v:
Brain Research. 1038:41-49
Ischemia/hypoxia (I/H) causes severe perinatal brain disorders such as cerebral palsy. The neonatal brain possesses much plasticity, and to enhance new cell production would be an innovative means of therapy for such disorders. In order to elucidate