Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Shokichi, Tsukamoto"'
Autor:
Arata Ishii, Shokichi Tsukamoto, Naoya Mimura, Yurie Miyamoto-Nagai, Yusuke Isshiki, Shinichiro Matsui, Sanshiro Nakao, Asuka Shibamiya, Yutaro Hino, Kensuke Kayamori, Nagisa Oshima-Hasegawa, Tomoya Muto, Yusuke Takeda, Tomoki Suichi, Sonoko Misawa, Chikako Ohwada, Koutaro Yokote, Satoshi Kuwabara, Chiaki Nakaseko, Hiroyuki Takamatsu, Emiko Sakaida
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal protein [M-protein], and skin changes) is a rare systemic disorder characterized by various symptoms caused by underlying plasma cell (PC) dyscrasia. Detection of monoc
Externí odkaz:
https://doaj.org/article/9b8f610b006b45589b8f86626a22aab6
Autor:
Yusuke Isshiki, Motohiko Oshima, Naoya Mimura, Kensuke Kayamori, Yurie Miyamoto-Nagai, Masahide Seki, Yaeko Nakajima-Takagi, Takashi Kanamori, Eisuke Iwamoto, Tomoya Muto, Shokichi Tsukamoto, Yusuke Takeda, Chikako Ohwada, Sonoko Misawa, Jun-ichiro Ikeda, Masashi Sanada, Satoshi Kuwabara, Yutaka Suzuki, Emiko Sakaida, Chiaki Nakaseko, Atsushi Iwama
Publikováno v:
JCI Insight, Vol 7, Iss 20 (2022)
POEMS syndrome is a rare monoclonal plasma cell disorder, with unique symptoms distinct from those of other plasma cell neoplasms, including high serum VEGF levels. Because the prospective isolation of POEMS clones has not yet been successful, their
Externí odkaz:
https://doaj.org/article/1465a2b380054f029fc2853ac8d0fd0e
Autor:
Yurie Nagai, Naoya Mimura, Ola Rizq, Yusuke Isshiki, Motohiko Oshima, Mohamed Rizk, Atsunori Saraya, Shuhei Koide, Yaeko Nakajima-Takagi, Makiko Miyota, Tetsuhiro Chiba, Nagisa Oshima-Hasegawa, Tomoya Muto, Shokichi Tsukamoto, Shio Mitsukawa, Yusuke Takeda, Chikako Ohwada, Masahiro Takeuchi, Tohru Iseki, Chiaki Nakaseko, William Lennox, Josephine Sheedy, Marla Weetall, Koutaro Yokote, Atsushi Iwama, Emiko Sakaida
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The novel small molecule PTC596 inhibits microtubule polymerization and its clinical development has been initiated for some solid cancers. We herein investigated the preclinical efficacy of PTC596 alone and in combination with proteasome in
Externí odkaz:
https://doaj.org/article/481913bfae7549a8909dc48c57cf66bb
Autor:
Arata Ishii, Shokichi Tsukamoto, Tatsuzo Mishina, Shintaro Izumi, Yurie Nagai, Miki Yamazaki, Yutaro Hino, Kensuke Kayamori, Nagisa Oshima-Hasegawa, Tomoya Muto, Shio Mitsukawa, Yusuke Takeda, Naoya Mimura, Chikako Ohwada, Chiaki Nakaseko, Jun-ichiro Ikeda, Emiko Sakaida
Publikováno v:
Leukemia Research Reports, Vol 16, Iss , Pp 100278- (2021)
A 45-year-old woman was diagnosed with myelodysplastic syndrome (MDS) with trisomy 8 and Behçet-like disease (BLD) with multiple colorectal ulcers. Nonspecific inflammatory cells were infiltrated in the intestinal mucosa, whereas fluorescence in sit
Externí odkaz:
https://doaj.org/article/393c811684ac4cb4948e5a4ed89d09a4
Autor:
Koji Takaishi, Masahiro Takeuchi, Shokichi Tsukamoto, Naoya Takayama, Motohiko Oshima, Kenji Kimura, Yusuke Isshiki, Kensuke Kayamori, Yutaro Hino, Nagisa Oshima-Hasegawa, Shio Mitsukawa, Yusuke Takeda, Naoya Mimura, Chikako Ohwada, Tohru Iseki, Sou Nakamura, Koji Eto, Atsushi Iwama, Koutaro Yokote, Chiaki Nakaseko, Emiko Sakaida
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Externí odkaz:
https://doaj.org/article/c57643ca72a24b709c0e3e521a23f0a4
Autor:
Tomoki, Suichi, Sonoko, Misawa, Yukari, Sekiguchi, Kazumoto, Shibuya, Keigo, Nakamura, Hiroki, Kano, Yuya, Aotsuka, Ryo, Otani, Marie, Morooka, Shokichi, Tsukamoto, Yusuke, Takeda, Naoya, Mimura, Chikako, Ohwada, Emiko, Sakaida, Satoshi, Kuwabara
Publikováno v:
Internal Medicine. 61:2567-2572
Objective Immunomodulatory drugs and proteasome inhibitors are therapeutic options for polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome. This study aimed to evaluate the efficacy and safety of the
Autor:
Yutaro Hino, Akira Watanabe, Rio Seki, Shokichi Tsukamoto, Yusuke Takeda, Emiko Sakaida, Katsuhiko Kamei
Publikováno v:
Journal of Fungi, Vol 7, Iss 10, p 806 (2021)
Invasive fungal disease (IFD) in patients with haematological disorders is a fatal disease, making rapid identification and treatment crucial. However, the identification of the causative fungus is often difficult, sometimes even impossible. There ha
Externí odkaz:
https://doaj.org/article/09e3e6fa6b4b46d39c66186df2507718
Autor:
Ayako Nakamura, Chikako Ohwada, Masahiro Takeuchi, Yusuke Takeda, Shokichi Tsukamoto, Naoya Mimura, Oshima-Hasegawa Nagisa, Yasumasa Sugita, Hiroaki Tanaka, Hisashi Wakita, Nobuyuki Aotsuka, Kosei Matsue, Koutaro Yokote, Osamu Ohara, Chiaki Nakaseko, Emiko Sakaida
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221941 (2019)
We investigated the feasibility of using next-generation sequencing (NGS) technique using molecular barcoding technology to detect MYD88 L265P mutation in unselected peripheral blood mononuclear cells (PBMCs) in 52 patients with Waldenström's macrog
Externí odkaz:
https://doaj.org/article/865fc6461bc047078c345fa256bd41ec
Autor:
Irene M. Ghobrial, Elisabeth M. Battinelli, Aldo M. Roccaro, Jodi Forward, Antonio Sacco, Daisy Huynh, Karma Z. Salem, Salomon Manier, Katsutoshi Kokubun, Yuji Mishima, Chia-Jen Liu, Michele Moschetta, Yawara Kawano, Kelly E. Johnson, Jihye Park, Shokichi Tsukamoto, Satoshi Takagi
5TGM1 cells co-localized with platelets in femur of syngeneic murine model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82bb4d8629e3fe2a439ef88697fcfbb7
https://doi.org/10.1158/1078-0432.22465209.v1
https://doi.org/10.1158/1078-0432.22465209.v1
Autor:
Irene M. Ghobrial, Elisabeth M. Battinelli, Aldo M. Roccaro, Jodi Forward, Antonio Sacco, Daisy Huynh, Karma Z. Salem, Salomon Manier, Katsutoshi Kokubun, Yuji Mishima, Chia-Jen Liu, Michele Moschetta, Yawara Kawano, Kelly E. Johnson, Jihye Park, Shokichi Tsukamoto, Satoshi Takagi
Purpose: Tumor cell–platelet interactions contribute to tumor progression and metastasis in solid tumors. However, the role of platelets in hematological malignancies is not clear. We investigated the association of platelet activation status with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b61d5f3f2ff258f4df66d49f4cc0ac1
https://doi.org/10.1158/1078-0432.c.6525945.v1
https://doi.org/10.1158/1078-0432.c.6525945.v1