Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shoji Shiraishi"'
Autor:
Toru Marubayashi, Youichi Itoyama, Shoji Shiraishi, Yukitaka Ushio, Masato Kochi, Isao Kitamura
Publikováno v:
Journal of Neurosurgery. 99:106-114
Object. The goal of this study was to confirm the effectiveness of our novel treatment strategy, neoadjuvant therapy (NAT) consisting of combined chemo- and radiotherapy, which are performed before complete excision of residual tumor in patients with
Autor:
Shoji Shiraishi, Takanori Kamiryo, Masato Kochi, Jun Ichi Kuratsu, Hideo Nakamura, Hirofumi Hirano, Yukitaka Ushio, Kenji Tada, Hideyuki Saya
Publikováno v:
Journal of Neurosurgery. 95:651-659
Object. The most frequent genetic abnormality in human malignant gliomas is loss of heterozygosity (LOH) on chromosome 10. Candidate genes on chromosome 10 that are associated with the prognosis of patients with anaplastic astrocytoma (AA) and gliobl
Autor:
Shoji Shiraishi, Takahiro Kimura, Yukitaka Ushio, Tazuko Iwasaki, Takeshi Kino, Keizo Yamamoto, Hideo Takeshima, Isao Kitamura, Kenji Tada, Tomoaki Goto, Yoshiki Saito, Shozaburo Uemura, Jun Ichi Kuratsu, Masato Kochi, Toru Nishi
Publikováno v:
Journal of Neuro-Oncology. 49:63-70
This prospective randomized trial was performed to compare the effectiveness of intra-arterial ACNU with intravenous ACNU in newly diagnosed patients with supratentorial glioblastoma. The primary end points were overall survival and progression-free
Autor:
Naoki, Shinojima, Kenji, Tada, Shoji, Shiraishi, Takanori, Kamiryo, Masato, Kochi, Hideo, Nakamura, Keishi, Makino, Hideyuki, Saya, Hirofumi, Hirano, Jun-Ichi, Kuratsu, Koji, Oka, Yasuji, Ishimaru, Yukitaka, Ushio
Publikováno v:
Cancer research. 63(20)
Glioblastoma multiforme (GBM) frequently involves amplification and alteration of the epidermal growth factor receptor (EGFR) gene, resulting in overexpression of varied mutations, including the most common mutation, EGFRvIII, as well as wild-type EG
Autor:
Yukitaka Ushio, Masato Kochi, Shoji Shiraishi, Naoki Shinojima, Jun Ichi Kuratsu, Kenji Tada, Takanori Kamiryo, Hideyuki Saya
Publikováno v:
Neuro-oncology. 5(4)
Neurofibromatosis 1 (NF1) is an autosomal dominant disorder that predisposes sufferers to various forms of neoplasia. Among affected individuals, 15%-20% develop astrocytomas, especially pilocytic astrocytomas (PA), which are benign and classified as
Publikováno v:
Neurosurgery. 54(2)
OBJECTIVE O 6-Methylguanine-deoxyribonucleic acid methyltransferase (MGMT) is a deoxyribonucleic acid repair protein associated with the chemoresistance of chloroethylnitrosoureas. We investigated whether MGMT promoter hypermethylation is associated
Autor:
Yukitaka Ushio, Jun Ichi Kuratsu, Shoji Shiraishi, Kenji Tada, Hideyuki Saya, Hideo Nakamura, Masato Kochi, Keishi Makino
Publikováno v:
Cancer. 95(2)
BACKGROUND The influence of p53 mutations on the biology of astrocytic tumors is controversial. p53 is thought to be inactivated in the early stage of gliomagenesis; however, what role its inactivation plays in the malignancy of gliomas remains unkno
Autor:
Kenji Tada, Yukitaka Ushio, Hideyuki Saya, Shoji Shiraishi, Hideo Nakamura, Naoki Shinojima, Jun Ichi Kuratsu, Masato Kochi, Takanori Kamiryo
Publikováno v:
Journal of neurosurgery. 96(5)
Object. One of the most frequent genetic abnormalities found in patients with glioblastoma multiforme (GBM) is homozygous deletion of the p16 tumor suppressor gene. The authors investigated whether this deletion is associated with prognosis in patien
Autor:
Kenji Tada, Kimio Yoshizato, Yukitaka Ushio, Jun Ichi Kuratsu, Tomoaki Goto, Takeshi Kino, Hideo Takeshima, Shoji Shiraishi, Masato Kochi, Gunter A. Hofmann, Takahiro Kimura, Sukhendu B. Dev, Toru Nishi
Publikováno v:
International Journal of Oncology.
Electroporation, a standard laboratory method of introducing exogenous molecules into cells, has been gaining importance as a very effective non-viral physical technique of gene delivery. In this study, we have used subcutaneous model of the C6 rat g
Publikováno v:
Transactions of the Iron and Steel Institute of Japan. 24:891-898