Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Shoji Masumori"'
Autor:
Keiichi Itoh1,2, Shoji Masumori2, Daisuke Mukai2, Hiroyuki Sakakibara3, Michiko Yasuda4, Kayoko Shimoi1 shimoi@u-shizuoka-ken.ac.jp
Publikováno v:
Journal of Toxicological Sciences. 2019, Vol. 44 Issue 4, p273-282. 10p.
Autor:
Gen Fujii, Takahiro Hamoya, Keiji Wakabayashi, Aya Nagano, Wakana Onuma, Daichi Asai, Michihiro Mutoh, Satoru Takahashi, Shingo Miyamoto, Noriyuki Miyoshi, Susumu Tomono, Shoji Masumori
Publikováno v:
Nutrition and Cancer. 69:855-861
Colorectal cancer is one of the leading causes of death worldwide. Reactive oxygen species produce oxidative stress and contribute to colorectal carcinogenesis. Because dietary citrus has been shown to reduce oxidative stress, we investigated the eff
Autor:
Jin Tanaka, Jyoji Yamate, Shoji Masumori, Makoto Hayashi, Masahito Fukumuro, Miho Nagai, Sawako Kasamoto, Maya Ueda
Publikováno v:
Experimental and Toxicologic Pathology. 69:187-191
According to the International Conference on Harmonization Guidance on Genotoxicity Testing and Data Interpretation for Pharmaceuticals Intended for Human Use (ICH S2(R1)), a positive response in any in vitro assay necessitates additional in vivo tes
Autor:
Makoto Hayashi, Shoji Masumori
Publikováno v:
The Micronucleus Assay in Toxicology ISBN: 9781788011341
The micronucleus assay is one of the genotoxicity assays used to detect chromosomal aberration induction in vivo. Rodent micronucleus assay using erythropoietic cells has been used most widely for chemical safety in the risk assessment of human healt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6044ed697e68280939078a4733684e8c
https://doi.org/10.1039/9781788013604-00128
https://doi.org/10.1039/9781788013604-00128
Autor:
Hiroyuki Sakakibara, Kayoko Shimoi, Shoji Masumori, Keiichi Itoh, Michiko T. Yasuda, Daisuke Mukai
Publikováno v:
The Journal of toxicological sciences. 44(4)
Previously, we reported that the frequency of micronucleated reticulocytes (MNRETs) in the peripheral blood of male C3H/He mice intraperitoneally administered ethylnitrosourea (ENU) (25 mg/kg body weight) in the dark period (zeitgeber time, ZT15) was
Autor:
Takashi Shimada, Masakazu Kakuni, Masahito Fukumuro, Makoto Hayashi, Yuji Ishida, Chise Tateno, Shoji Masumori
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis. 839
Genotoxicity assays are characterized by a method, an in vitro or in vivo target, and an endpoint. Many cell types have been used as targets, including bacterial cells, cultured mammalian cells, and rodent cells in vivo. Human cells are the most impo
Autor:
Yohei Fujiishi, Maya Ueda, Shoji Masumori, Makoto Hayashi, Michiyo Oba, Yuriko Kougo, Jin Tanaka, Miho Nagai, Kazufumi Kawasako, Masakatsu Natsume, Shigeaki Takami, Fuyumi Uno, Masahito Fukumuro, Emiko Okada, Yumi Wako, Wakako Ohyama, Ayaka Akahori, Kazunori Narumi
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. :51-55
Repeated-dose liver, bone marrow, and gastrointestinal tract micronucleus assays that use young adult rats were evaluated in a collaborative study that was organized by the Japanese Environmental Mutagen Society–Mammalian Mutagenicity Study Group.
Autor:
Keiichi Itoh1,2, Shoji Masumori2, Madoka Nakajima2, Makoto Hayashi2, Hiroyuki Sakakibara1, Kayoko Shimoi1,3 shimoi@u-shizuoka-ken.ac.jp
Publikováno v:
Journal of Toxicological Sciences. Apr2012, Vol. 37 Issue 2, p427-430. 4p.
Autor:
Shigehisa Endoh, Masayo Hosoi, Makoto Hayashi, Masato Naya, Norihiro Kobayashi, Shoji Masumori, Junko Nakanishi, Fuyumi Uno, Junko Maru, Madoka Nakajima, Makoto Ema
Publikováno v:
Journal of Applied Toxicology. 33:1053-1060
The genotoxicity of multi-walled carbon nanotubes (MWCNTs) was evaluated in vivo with comet assays using the lung cells of rats given MWCNTs. The MWCNTs were intratracheally instilled as a single dose at 0.2 or 1.0 mg kg–1 or a repeated dose at 0.0
Autor:
Makoto Hayashi, Madoka Nakajima, Kayoko Shimoi, Shoji Masumori, Keiichi Itoh, Hiroyuki Sakakibara
Publikováno v:
The Journal of Toxicological Sciences. 37:427-430
Mammals, including human beings, have a circadian clock system to regulate behavioral and physiological processes. In this study, we investigated the effect of dosing time on micronucleus induction in the bone marrow by evaluating the frequencies of