Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Shoji, Yokochi"'
Autor:
Kohei Shitara, Satoshi Ueha, Shigeyuki Shichino, Hiroyasu Aoki, Haru Ogiwara, Tetsuya Nakatsura, Toshihiro Suzuki, Manami Shimomura, Toshiaki Yoshikawa, Kayoko Shoda, Shigehisa Kitano, Makiko Yamashita, Takayuki Nakayama, Akihiro Sato, Sakiko Kuroda, Masashi Wakabayashi, Shogo Nomura, Shoji Yokochi, Satoru Ito, Kouji Matsushima, Toshihiko Doi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Background Transient CD4+ T cell depletion led to the proliferation of tumor-specific CD8+ T cells in the draining lymph node and increased infiltration of PD-1+CD8+ T cells into the tumor, which resulted in strong anti-tumor effects in tumo
Externí odkaz:
https://doaj.org/article/f3fa5960399a4030b38ca80859495c2b
Autor:
Chang-Yu Chen, Satoshi Ueha, Yoshiro Ishiwata, Shoji Yokochi, De Yang, Joost J. Oppenheim, Haru Ogiwara, Shigeyuki Shichino, Shungo Deshimaru, Francis H. W. Shand, Shiro Shibayama, Kouji Matsushima
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Transient depletion of CD4+ T cells results in tumor suppression and survival benefit in murine models; however, the tumor progression and recurrence still occur over more long-term monitoring of mice. Thus, we explored an additio
Externí odkaz:
https://doaj.org/article/66c6295675c24b7c82a27034e116f967
Autor:
Kouji Matsushima, Shiro Shibayama, Tatsuro Ogawa, Hiroyasu Aoki, Yuzuka Kanno, Shungo Deshimaru, Haru Ogiwara, Joost J. Oppenheim, De Yang, Shoji Yokochi, Shigeyuki Shichino, Yoshiro Ishiwata, Satoshi Ueha, Chang-Yu Chen
The expansion of intratumoral stem-like/progenitor exhausted CD8+ T (Tstem/Tpex) cells provides a potential approach to improve the therapeutic efficacy of immune checkpoint blockade (ICB). Thus, here we demonstrate a strategy to facilitate Tstem/Tpe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c68af7bd2adb3ecdb017878aeb93bc4
https://doi.org/10.1158/2326-6066.c.6550191
https://doi.org/10.1158/2326-6066.c.6550191
Autor:
Kouji Matsushima, Shiro Shibayama, Tatsuro Ogawa, Hiroyasu Aoki, Yuzuka Kanno, Shungo Deshimaru, Haru Ogiwara, Joost J. Oppenheim, De Yang, Shoji Yokochi, Shigeyuki Shichino, Yoshiro Ishiwata, Satoshi Ueha, Chang-Yu Chen
Supplementary Figures 1-5 and Supplementary table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57412bcc6d7812a93ce9b1841a5fc87f
https://doi.org/10.1158/2326-6066.22543263
https://doi.org/10.1158/2326-6066.22543263
Autor:
Kouji Matsushima, Satoru Ito, Kazuhiro Kakimi, Francis H.W. Shand, Etsuko Toda, Yuya Terashima, Shigeyuki Shichino, Kosuke Hachiga, Takuya Nakajima, Krishant Chand, Haru Ogiwara, Yoshiro Ishiwata, Shoji Yokochi, Satoshi Ueha
Table S1. Antibodies for flow cytometry and immunohistostaining. Table S2. Primers and probes used in real-time PCR. Supplementary Figure S1. Generation of B16F10-ÃŽ?hLNGFR transfected cells. Supplementary Figure S2. Optimization of the timing and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f66545ae48cce7c67741cc6100a5e45
https://doi.org/10.1158/2326-6066.22538611
https://doi.org/10.1158/2326-6066.22538611
Autor:
Kouji Matsushima, Satoru Ito, Kazuhiro Kakimi, Francis H.W. Shand, Etsuko Toda, Yuya Terashima, Shigeyuki Shichino, Kosuke Hachiga, Takuya Nakajima, Krishant Chand, Haru Ogiwara, Yoshiro Ishiwata, Shoji Yokochi, Satoshi Ueha
Depletion of CD4+ cells in tumor-bearing mice has strong antitumor effects. However, the mechanisms underlying these effects and the therapeutic benefits of CD4+ cell depletion relative to other immunotherapies have not been fully evaluated. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c34ef412ef4cfc3bcc8fd169115d3312
https://doi.org/10.1158/2326-6066.c.6548827.v1
https://doi.org/10.1158/2326-6066.c.6548827.v1
Autor:
Tatsuro Ogawa, Shiro Shibayama, De Yang, Haru Ogiwara, Hiroyasu Aoki, Yuzuka Kanno, Joost J. Oppenheim, Yoshiro Nagakute Aza-arata Ishiwata, Shoji Yokochi, Kouji Matsushima, Shungo Deshimaru, Chang Yu Chen, Shigeyuki Shichino, Satoshi Ueha
Publikováno v:
Cancer Immunol Res
The expansion of intratumoral stem-like/progenitor exhausted CD8+ T (Tstem/Tpex) cells provides a potential approach to improve the therapeutic efficacy of immune checkpoint blockade (ICB). Thus, here we demonstrate a strategy to facilitate Tstem/Tpe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e788cb6adb2153bc63e4758e407aa2b9
https://doi.org/10.1158/2326-6066.cir-21-0265
https://doi.org/10.1158/2326-6066.cir-21-0265
Autor:
Yoshiro Ishiwata, Chang Yu Chen, Joost J. Oppenheim, Tatsuro Ogawa, Shiro Shibayama, Haru Ogiwara, De Yang, Shungo Deshimaru, Yuzuka Kanno, Satoshi Ueha, Koji Matsushima, Shigeyuki Shichino, Shoji Yokochi
BackgroundThe expansion of intratumoral stem-like CD8+ T (Tstem) cells provides a potential approach to improving the therapeutic efficacy of immune checkpoint blockade (ICB). Thus, here we demonstrate a strategy to facilitate Tstem cell expansion by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::801358abc60a0c99cb74029ecba843aa
https://doi.org/10.1101/2020.12.15.422990
https://doi.org/10.1101/2020.12.15.422990
Autor:
Shiro Shibayama, Satoru Ito, Kouji Matsushima, Yoshiro Ishiwata, Shoji Yokochi, Yusuke Shono, Satoshi Ueha, Mizuha Kosugi-Kanaya
Publikováno v:
Cancer Science. 108:1967-1973
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is not only a well-established immunotherapy for hematologic malignancies, but is potentially useful for treating solid tumors refractory to available therapies. However, application of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ebf337ebe4a0aea5b72336a6cb343ff
https://doi.org/10.1111/cas.13346
https://doi.org/10.1111/cas.13346
Autor:
Satoru Ito, Toshihiro Suzuki, Makiko Yamashita, Takayuki Nakayama, Sakiko Kuroda, Hiroyasu Aoki, Manami Shimomura, Shoji Yokochi, Toshiaki Yoshikawa, Shogo Nomura, Satoshi Ueha, Kohei Shitara, Kouji Matsushima, Haru Ogiwara, Tetsuya Nakatsura, Shigeyuki Shichino, Akihiro Sato, Toshihiko Doi, Shigehisa Kitano, Kayoko Shoda, Masashi Wakabayashi
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Background Transient CD4+ T cell depletion led to the proliferation of tumor-specific CD8+ T cells in the draining lymph node and increased infiltration of PD-1+CD8+ T cells into the tumor, which resulted in strong anti-tumor effects in tumor-bearing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdf9745586e64d4e764eb767ef0e7ba3
https://doi.org/10.1186/s40425-019-0677-y
https://doi.org/10.1186/s40425-019-0677-y