Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Shoichiro Miyatake"'
Publikováno v:
Biochemical and biophysical research communications. 501(2)
Members of the BTB-ZF transcription factor family play important roles in lymphocyte development. During T cell development, ZNF131, a BTB-ZF protein, is critical for the double-negative (DN) to double-positive (DP) transition and is also involved in
Autor:
Masato Taoka, Tomokatsu Ikawa, Osamu Koiwai, Shoichiro Miyatake, Hisao Masai, Toshiaki Isobe, Hiroshi Kawamoto, Choji Taya, Tomohiro Iguchi, Kazuhisa Aoki, Hiroshi Yoshitani, Makiko Toma-Hirano
Publikováno v:
The Journal of Immunology. 195:982-993
Many members of the BTB-ZF family have been shown to play important roles in lymphocyte development and function. The role of zinc finger Znf131 (also known as Zbtb35) in T cell lineage was elucidated through the production of mice with floxed allele
Autor:
Kazuhisa Aoki, Osamu Kaminuma, Noriko Sato, Shoichiro Miyatake, Atsumi Yamaguchi, Takumi Hosozawa
Publikováno v:
The Journal of Immunology. 182:7698-7707
Demethylation of transcriptional regulatory elements and gene coding regions is an important step in the epigenetic regulation of gene expression. Several noncoding conserved regions are required for the efficient transcription of cytokine genes. In
Autor:
Edgar Serfling, Shoichiro Miyatake, Arthur Schmidt, Mithilesh Kumar Jha, Stefan Klein-Hessling, Tobias Bopp, Edgar Schmitt
Publikováno v:
Journal of Biological Chemistry. 283:31030-31037
Elevated intracellular cyclic AMP levels, which suppress the proliferation of naive T cells and type 1 T helper (Th1) cells are a property of T helper 2 (Th2) cells and regulatory T cells. While cyclic AMP signals interfere with the IL-2 promoter ind
Autor:
Yuichiro Kajiyama, Takayuki Ohtomo, Shoichiro Miyatake, Akio Mori, Noriaki Kobayashi, Makiko Umezu-Goto, Osamu Kaminuma
Publikováno v:
International Archives of Allergy and Immunology. 146:2-6
Background: Conserved noncoding sequence-1 (CNS-1) is an important regulatory element for T helper 2 cytokine expression. IL-4, IL-5 and IL-13 expression as well as serum IgE level were attenuated in CNS-1–/– mice. Method: CNS-1–/– and CNS-1+
Autor:
Sahori Namiki, Yumiko Kamogawa-Schifter, Makiko Toma-Hirano, Ken-ichi Arai, Shoichiro Miyatake
Publikováno v:
European Journal of Immunology. 37:2707-2714
Ly49Q is expressed on peripheral mouse plasmacytoid dendritic cells (pDC). Immature Ly49Q-negative pDC precursors acquire Ly49Q in the bone marrow and then migrate into the periphery. While searching for molecules that regulate pDC maturation, we fou
Autor:
Shoichiro Miyatake, Kanako Ohsawa, Mauro Giacca, Hisao Masai, Richard M. Locksley, Takumi Hosozawa, Atsumi Yamaguchi, Toshiro Hayashida, Masako Oda
Publikováno v:
Scopus-Elsevier
CIÊNCIAVITAE
CIÊNCIAVITAE
Lineage commitment of Th cells is associated with the establishment of specific transcriptional programs of cytokines. However, how Th cell differentiation affects the program of DNA replication has not been addressed. To gain insight into interplays
Autor:
Akio Mori, Osamu Kaminuma, Shigeko Inokuma, Tomomi Hashimoto, Shoichiro Miyatake, Fujiko Kitamura, Noriko Kitamura
Publikováno v:
International Archives of Allergy and Immunology. 137:55-59
Background: Helper T cells and T cell cytokines play central roles in allergic disorders including bronchial asthma. We reported enhanced IL-5 production by peripheral blood T cells of asthmatic patients. A transcription factor, GATA-3, has been impl
Autor:
Nobuhiro Ishida, Shoichiro Miyatake, Kazuhisa Aoki, Yutaka Sanai, Toshiyasu Kuba, Masao Kawakita
Publikováno v:
Genomics. 85:106-116
We report the molecular cloning of SLC35D2, a novel member of the SLC35 nucleotide sugar transporter family. The gene SLC35D2 maps to chromosome 9q22.33. SLC35D2 cDNA codes for a hydrophobic protein consisting of 337 amino acid residues with 10 putat
Publikováno v:
Immunology. 106:212-221
We have previously reported that human granulocyte-macrophage colony-stimulating factor (hGM-CSF) causes a stage-specific inhibition of T-cell receptor (TCR) alphabeta cell development in the thymus of transgenic mice constitutively expressing the hG