Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Shoichiro Inokuchi"'
Autor:
Tetsuhiro Tanaka, Shoichi Maruyama, Noriharu Chishima, Hiroki Akiyama, Koji Shimamoto, Shoichiro Inokuchi, Keiji Yokota, Asuka Ozaki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Chronic kidney disease (CKD) guidelines recommend early identification and intervention to delay the progression of CKD. The Kidney Disease: Improving Global Outcomes (KDIGO) heatmap is widely used for risk evaluation in CKD management; howe
Externí odkaz:
https://doaj.org/article/36dfbefc5f48479a84cb4e5537f638d9
Autor:
Shoichiro Inokuchi, Koji Shimamoto
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionRomosozumab is a monoclonal antibody approved for osteoporosis which targets sclerostin, an endogenous inhibitor of Wnt/β-catenin pathway. Given the essential roles of the Wnt/β-catenin pathway in various tissues, we hypothesized romoso
Externí odkaz:
https://doaj.org/article/8bfce2cb4fd349a48b7a28c72d6def5b
Publikováno v:
Current Therapeutic Research, Vol 99, Iss , Pp 100724- (2023)
ABSTRACT: Background: Chronic constipation is a common condition affecting people of all ages; therefore, the socioeconomic burden of chronic constipation is nonnegligible. Elobixibat (ELO), an ileal bail acid transport inhibitor, was launched in Jap
Externí odkaz:
https://doaj.org/article/1a9c5ae36db745f4809ab6849fda70fd
Autor:
Miki Nakano, Masahiro Ayano, Kazuo Kushimoto, Shotaro Kawano, Kazuhiko Higashioka, Shoichiro Inokuchi, Hiroki Mitoma, Yasutaka Kimoto, Mitsuteru Akahoshi, Nobuyuki Ono, Yojiro Arinobu, Koichi Akashi, Takahiko Horiuchi, Hiroaki Niiro
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract CD226 is an activating receptor expressed on the cell surface of natural killer cells and T cells. Although CD226 polymorphism is known to be involved in systemic lupus erythematosus (SLE), the involvement of soluble CD226 (sCD226) in SLE is
Externí odkaz:
https://doaj.org/article/184c7d5b436a488e8be4ca2c72aa394a
Autor:
Miki Nakano, Masahiro Ayano, Kazuo Kushimoto, Shotaro Kawano, Kazuhiko Higashioka, Shoichiro Inokuchi, Hiroki Mitoma, Yasutaka Kimoto, Mitsuteru Akahoshi, Nobuyuki Ono, Yojiro Arinobu, Koichi Akashi, Takahiko Horiuchi, Hiroaki Niiro
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundCD226, an activating receptor expressed on the surface of natural killer (NK) cells and T cells, is also seen on B cells and CD226 polymorphism is associated with systemic lupus erythematosus (SLE). Because the specific roles of CD226+ B ce
Externí odkaz:
https://doaj.org/article/60435d1459ed459082a1816d2fbbd4c8
Autor:
Masato Takeuchi, Shoichiro Inokuchi, Takeshi Kimura, Narumi Eguchi, Koji Kawakami, Tai Takahashi
Publikováno v:
Annals of Clinical Epidemiology. 5:5-12
Autor:
Shoichiro, Inokuchi, Hiroki, Mitoma, Shotaro, Kawano, Masahiro, Ayano, Yasutaka, Kimoto, Mitsuteru, Akahoshi, Yojiro, Arinobu, Koichi, Akashi, Takahiko, Horiuchi, Hiroaki, Niiro
Publikováno v:
Pathogenesis of rheumatoid arthritis: one year in review 2022. 40:522-531
Emerging evidence has shown the importance of inflammasome activation in the progression of autoimmune diseases. In this study, we aimed to identify the main cell types activating inflammasome in autoimmune diseases and to clarify the intracellular p
Autor:
Yojiro Arinobu, Hiroki Mitoma, Hiroaki Niiro, Tomofumi Tatsutani, Takahiko Horiuchi, Koji Mishima, Tomoya Nishida, Koichi Akashi, Yasutaka Kimoto, Mitsuteru Akahoshi, Masahiro Ayano, Shoichiro Inokuchi
Publikováno v:
Modern Rheumatology Case Reports. 5:278-284
A 53-year-old woman was admitted to our hospital for headache secondary to an acute subdural haematoma in the right cerebellar tentorium. She had been diagnosed with systemic lupus erythematosus (S...
Autor:
Hiroki Mitoma, Shoichiro Inokuchi, Shota Nakano, Yojiro Arinobu, Hiroaki Niiro, Shotaro Kawano, Yasutaka Kimoto, Masahiro Ayano, Koichi Akashi, Hiroshi Tsukamoto, Takahiko Horiuchi, Mitsuteru Akahoshi
Publikováno v:
The Journal of Immunology. 204:2088-2097
DNase 1–like 3 (DNase1L3), which belongs to DNase1 family, was originally identified as one of apoptosis- and necrosis-related endonucleases that fragmentate intranucleosomal DNA. A loss-of-function mutation has been reported in murine models of sy
Autor:
Yojiro Arinobu, Hiroaki Niiro, Tomofumi Tatsutani, Koichi Akashi, Remi Tokushima, Shoichiro Inokuchi, Takeyuki Goto, Koji Mishima, Yoji Nagasaki
Publikováno v:
Nihon Naika Gakkai Zasshi. 109:603-610