Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Shoichiro, Horita"'
Autor:
Yuko Maejima, Shoko Yokota, Masaru Shimizu, Shoichiro Horita, Daisuke Kobayashi, Akihiro Hazama, Kenju Shimomura
Publikováno v:
Nutrition & Metabolism, Vol 18, Iss 1, Pp 1-15 (2021)
Abstract Background Feeding rhythm disruption contributes to the development of obesity. The receptors of glucagon-like peptide-1 (GLP-1) are distributed in the wide regions of the brain. Among these regions, GLP-1 receptors (GLP-1R) are expressed in
Externí odkaz:
https://doaj.org/article/e2c9447372424a83bcc795d655f055d1
Autor:
Shoichiro Horita, Tomoyuki Ono, Saul Gonzalez-Resines, Yuko Ono, Megumi Yamachi, Songji Zhao, Carmen Domene, Yuko Maejima, Kenju Shimomura
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Developmental delay, epilepsy, and neonatal diabetes (DEND) syndrome, the most severe end of neonatal diabetes mellitus, is caused by mutation in the ATP-sensitive potassium (KATP) channel. In addition to diabetes, DEND patients present musc
Externí odkaz:
https://doaj.org/article/f773962797f64e77ad79d1b308605126
Autor:
Yuki Shiimura, Shoichiro Horita, Akie Hamamoto, Hidetsugu Asada, Kunio Hirata, Misuzu Tanaka, Kenji Mori, Tomoko Uemura, Takuya Kobayashi, So Iwata, Masayasu Kojima
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Ghrelin is a gastric peptide hormone with important physiological functions, including growth hormone release and appetite-stimulating activity. Here, authors solved the crystal structure of the ghrelin receptor bound to antagonist and suggested a po
Externí odkaz:
https://doaj.org/article/e7526d5cb5754366b7a2d14fcf34c3e1
Publikováno v:
Nutrition & Metabolism, Vol 17, Iss 1, Pp 1-8 (2020)
Abstract Obesity is becoming one of the most severe global health problems. However, risk of developing normal weight obesity, where an individual has a high percentage of body fat despite a normal body mass index, is gaining attention since such ind
Externí odkaz:
https://doaj.org/article/7268b493e5364ab89e673053d3d02ad6
Autor:
Kenji Gonda, Takanori Akama, Takayuki Nakamura, Eiko Hashimoto, Naomi Kyoya, Yuichi Rokkaku, Yuko Maejima, Shoichiro Horita, Kazunoshin Tachibana, Noriko Abe, Tohru Ohtake, Kenju Shimomura, Koji Kono, Shigehira Saji, Seiichi Takenoshita, Eiji Higashihara
Publikováno v:
Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-6 (2019)
Abstract Background Autosomal dominant polycystic kidney disease is defined as an inherited disorder characterized by renal cyst formation due to mutations in the PKD1 or PKD2 gene, whereas tuberous sclerosis complex is an autosomal dominant neurocut
Externí odkaz:
https://doaj.org/article/549c962f85f84f4383118f94fe04f5c2
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-4 (2019)
Abstract Objectives In an aging population, an increase in the number of elderly cancer patients with cognitive impairment is expected. The possible association between cancer and cognitive impairment is important to elucidate, because it can have a
Externí odkaz:
https://doaj.org/article/2c0b9abf36f74dc5a48e70fa1cf93e11
Autor:
Tomoyuki Momma, Kenji Gonda, Yoshinori Akama, Eisei Endo, Daisuke Ujiie, Shotaro Fujita, Yuko Maejima, Shoichiro Horita, Kenju Shimomura, Shigehira Saji, Koji Kono, Rei Yashima, Fumiaki Watanabe, Kokichi Sugano, Tadashi Nomizu
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-6 (2019)
Abstract Background Lynch syndrome, is an autosomal dominantly inherited disease that predisposes individuals to a high risk of colorectal cancers, and some mismatch-repair genes have been identified as causative genes. The purpose of this study was
Externí odkaz:
https://doaj.org/article/9be6b609b23e4de0a85235d579ea1bbe
Autor:
Ryota Imai, Shingen Misaka, Shoichiro Horita, Shoko Yokota, Rie O’hashi, Yuko Maejima, Kenju Shimomura
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-6 (2018)
Abstract Objective Memantine, a drug for Alzheimer’s disease, is considered to suppress excessive stimulation of N-methyl-d-aspartic acid receptors and to prevent neuronal death. However, a recent report indicated that the neuronal KATP channel als
Externí odkaz:
https://doaj.org/article/79769b8189a34640a1f24a30f39e2406
Autor:
Shu Taira, Akari Ikeda, Shoko Kobayashi, Hitomi Shikano, Ryuzoh Ikeda, Yuko Maejima, Shoichiro Horita, Jun Yokoyama, Kenju Shimomura
Publikováno v:
Applied Sciences, Vol 11, Iss 13, p 6217 (2021)
We compared four derivatization reagents to analyze catecholamines and amino acids by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. 2,4,6-Trimethylpyrylium tetrafluoroborate (TMPy), 2,4-diphenyl-pyranylium tetrafluoroborate (
Externí odkaz:
https://doaj.org/article/4dc463eed1ff4e708b6d968dd94273b2
Autor:
Yuko Maejima1 maejimay@fmu.ac.jp, Shoichiro Horita1, Shoko Yokota1, Tomoyuki Ono1, Proks, Peter2, Hiromi Yoshida-Komiya3, Yoichi Ueta4, Katsuhiko Nishimori1, Shingen Misaka1, Kenju Shimomura1 shimomur@fmu.ac.jp
Publikováno v:
Journal of Food & Drug Analysis. 2021, Vol. 29 Issue 4, p653-675. 23p.