Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Shoichi Takikita"'
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 4, Iss C, Pp 25-29 (2015)
Hypomyelination in developing brain is often accompanied by congenital metabolic disorders. Menkes kinky hair disease is an X-linked neurodegenerative disease of impaired copper transport, resulting from a mutation of the Menkes disease gene, a trans
Externí odkaz:
https://doaj.org/article/7b4359e3461e4433b8460a187b5682b6
Autor:
Takashi Yagi, Eileen J McMahon, Shoichi Takikita, Ikuko Mohri, Glenn K Matsushima, Kinuko Suzuki
Publikováno v:
Neurobiology of Disease, Vol 16, Iss 1, Pp 98-109 (2004)
The twitcher mouse is an authentic murine model of a genetic demyelinating disease globoid cell leukodystrophy. Allogeneic bone marrow transplantation (BMT) in twitcher mice resulted in the clinicopathological improvement. Thus, using green fluoresce
Externí odkaz:
https://doaj.org/article/8faef5f6807f462a8361e1d19391bced
Autor:
Shoichi Takikita, Cynthia Schreiner, Rebecca Baum, Tao Xie, Evelyn Ralston, Paul H Plotz, Nina Raben
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15239 (2010)
PGC-1α is a transcriptional co-activator that plays a central role in the regulation of energy metabolism. Our interest in this protein was driven by its ability to promote muscle remodeling. Conversion from fast glycolytic to slow oxidative fibers
Externí odkaz:
https://doaj.org/article/29f1fd6a68f84f48a5f2b0ac27a9d057
Autor:
John R. Weis, Harumi Suzuki, Masayuki Kitajima, Kenshiro Oshima, Takeshi Otsubo, Taeko Dohi, Yuki I. Kawamura, Toshiyuki Takai, Ryunosuke Muro, Masahira Hattori, Takaho A. Endo, Hiroyo Oda, Tetsuro Toyoda, Yoichi Shinkai, Shoichi Takikita
Publikováno v:
The Journal of Immunology. 197:2269-2279
ESET/SETDB1, one of the major histone methyltransferases, catalyzes histone 3 lysine 9 (H3K9) trimethylation. ESET is critical for suppressing expression of retroviral elements in embryonic stem cells; however, its role in the immune system is not kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a88d3985164b6e0d82afce63aae709d
https://doi.org/10.4049/jimmunol.1502486
https://doi.org/10.4049/jimmunol.1502486
Autor:
Rebecca Baum, Sengen Xu, Masaaki Komatsu, Jack H. Van der Meulen, Cynthia Schreiner, Paul H. Plotz, Tao Xie, Evelyn Ralston, Rachel Myerowitz, Nina Raben, Kanneboyina Nagaraju, Shoichi Takikita
Publikováno v:
Autophagy. 6:1078-1089
Autophagy, an intracellular system for delivering portions of cytoplasm and damaged organelles to lysosomes for degradation/recycling, plays a role in many physiological processes and is disturbed in many diseases. We recently provided evidence for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfac534ba06fff6a8d6392f49714ae0
https://doi.org/10.4161/auto.6.8.13378
https://doi.org/10.4161/auto.6.8.13378
Autor:
Evelyn Ralston, Paul H. Plotz, Rebecca Baum, Nina Raben, Shoichi Takikita, Noboru Mizushima, Lauren Shea, Victoria Hill
Publikováno v:
Human Molecular Genetics. 17:3897-3908
The role of autophagy, a catabolic lysosome-dependent pathway, has recently been recognized in a variety of disorders, including Pompe disease, the genetic deficiency of the glycogen-degrading lysosomal enzyme acid-alpha glucosidase. Accumulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6dca7e70345fd838896969575af9c32
https://doi.org/10.1093/hmg/ddn292
https://doi.org/10.1093/hmg/ddn292
Autor:
Yoshihiro Urade, Kuriko Kagitani-Shimono, Ikuko Mohri, Takahisa Kanekiyo, Kinuko Suzuki, Issei Okazaki, Masako Taniike, Hyung Suk Kim, Shoichi Takikita, Kosuke Aritake, Takashi Yagi
Publikováno v:
Journal of Neurochemistry. 97:641-651
Lipocalin-type prostaglandin (PG) D synthase (L-PGDS) is a dually functional protein, acting both as a PGD2-synthesizing enzyme and as an extracellular transporter of various lipophilic small molecules. L-PGDS is expressed in oligodendrocytes (OLs) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6df1b559bc941e4b43985938b88f6f30
https://doi.org/10.1111/j.1471-4159.2006.03753.x
https://doi.org/10.1111/j.1471-4159.2006.03753.x
Publikováno v:
Congenital Anomalies. 45:9-13
The study presented here investigated the pathogenetic relationship among different types of neuronal migration disorders occurring simultaneously in the brain using an experimental model induced by ibotenate in hamsters. In the cerebral cortex, abno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5661c511c1bc2374156f3dceffe96cfb
https://doi.org/10.1111/j.1741-4520.2005.00054.x
https://doi.org/10.1111/j.1741-4520.2005.00054.x
Autor:
Chihiro Sawai, Tomoyuki Takano, Shoichi Takikita, Masaki Ohno, Toshihiro Sawai, Yoshihiro Takeuchi, Yuko Sakaue
Publikováno v:
Journal of the Japan Epilepsy Society. 23:114-120
1996年から2004年までの8年間に当科に入院したけいれん重積状態97例108機会に対するミダゾラム静注療法の有効性について検討した。基礎疾患はてんかん50機会、熱性けいれん37機会、急性
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d57d5b6c9d4085d62ac436c40bb97545
https://doi.org/10.3805/jjes.23.114
https://doi.org/10.3805/jjes.23.114
Autor:
Ikuko Mohri, Shoichi Takikita, Takashi Yagi, Kinuko Suzuki, Eileen J. McMahon, Glenn K. Matsushima
Publikováno v:
Neurobiology of Disease, Vol 16, Iss 1, Pp 98-109 (2004)
The twitcher mouse is an authentic murine model of a genetic demyelinating disease globoid cell leukodystrophy. Allogeneic bone marrow transplantation (BMT) in twitcher mice resulted in the clinicopathological improvement. Thus, using green fluoresce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e987da76a0f843b17d24ad3825e18b
https://doi.org/10.1016/j.nbd.2004.01.002
https://doi.org/10.1016/j.nbd.2004.01.002