Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Shoichi Kado"'
Autor:
Masao Togao, Shinnosuke Tajima, Takashi Kurakawa, Gaku Wagai, Jun Otsuka, Shoichi Kado, Koji Kawakami
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 6, Pp n/a-n/a (2021)
Abstract Several studies revealed that substantial artificial changes in the gut microbiota resulted in modification of hepatic cytochrome P450 3a (Cyp3a) in mice. Consequently, we hypothesized that “normal” variation of the gut microbiota might
Externí odkaz:
https://doaj.org/article/73de0c09ea594900a4773b80efdcf66d
Autor:
Keisuke Taniguchi, Tomo Suzuki, Tomomi Okamura, Akinobu Kurita, Gou Nohara, Satoru Ishii, Shoichi Kado, Akimitsu Takagi, Momomi Tsugane, Yoshiyuki Shishido
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Metastatic brain tumors are regarded as the most advanced stage of certain types of cancer; however, chemotherapy has played a limited role in the treatment of brain metastases. Here, we established murine models of brain metastasis using cell lines
Externí odkaz:
https://doaj.org/article/39157eec5a8c4744ab579f8c951d9381
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175497 (2017)
Each species of intestinal bacteria requires a nutritional source to maintain its population in the intestine. Dietary factors are considered to be major nutrients; however, evidence directly explaining the in situ utilization of dietary factors is l
Externí odkaz:
https://doaj.org/article/dec75d285cda4203a4708680ac49744e
Publikováno v:
Experimental Animals. 71:22-27
An incident reporting system (IRS) prevents possible adverse events by collecting and analyzing incidents that occur. However, few studies are available regarding IRSs in the laboratory animal field. This study aimed to develop an incident severity c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3873f52cfdfe8fbaee674adc3e17cd67
https://doi.org/10.1538/expanim.21-0073
https://doi.org/10.1538/expanim.21-0073
Autor:
Yoshiyuki Shishido, Akimitsu Takagi, Akinobu Kurita, Tomo Suzuki, Tomomi Okamura, Gou Nohara, Shoichi Kado, Keisuke Taniguchi, Satoru Ishii, Momomi Tsugane
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
Metastatic brain tumors are regarded as the most advanced stage of certain types of cancer; however, chemotherapy has played a limited role in the treatment of brain metastases. Here, we established murine models of brain metastasis using cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048c582a7c8dfb71f1412757f6c71804
https://doi.org/10.3389/fonc.2021.754365
https://doi.org/10.3389/fonc.2021.754365
Autor:
Koji Kawakami, Takashi Kurakawa, Shoichi Kado, Jun Otsuka, Shinnosuke Tajima, Masao Togao, Gaku Wagai
Publikováno v:
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 9, Iss 6, Pp n/a-n/a (2021)
Pharmacology Research & Perspectives, Vol 9, Iss 6, Pp n/a-n/a (2021)
Several studies revealed that substantial artificial changes in the gut microbiota resulted in modification of hepatic cytochrome P450 3a (Cyp3a) in mice. Consequently, we hypothesized that “normal” variation of the gut microbiota might also alte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7b0282d1543812f9c370cea26c786d
http://europepmc.org/articles/PMC8573722
http://europepmc.org/articles/PMC8573722
Publikováno v:
Biopharmaceutics & Drug Disposition
The link between drug‐metabolizing enzymes and gut microbiota is well established. In particular, hepatic cytochrome P450 (CYP) 3A activities are presumed to be affected by gut microbiota. However, there is no direct evidence that the gut microbiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5cf4be42d812e73a0e6d3d6945d85aa
https://pubmed.ncbi.nlm.nih.gov/32562497
https://pubmed.ncbi.nlm.nih.gov/32562497
Autor:
Ryota Tochinai, Shoichi Kado, Minoru Ando, Kayoko Komatsu, Yuriko Nagata, Tomo Suzuki, Junta Murakami, Masayoshi Kuwahara, Toshihide Kobayashi, Chie Hata
Publikováno v:
Journal of Toxicologic Pathology
Cardiotoxicity is a concern in the development of microtubule-disassembling agents (MDAs) as vascular-disrupting agents of tumors. This study investigated cardiotoxicity in rats induced by a single-dose of combretastatin A4 disodium phosphate (CA4DP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01090b37ee42b482d8b7fce4337c835e
https://doi.org/10.1293/tox.2018-0023
https://doi.org/10.1293/tox.2018-0023
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis. 844
The usefulness of the rat repeated-dose liver and gastrointestinal (GI) tract micronucleus (MN) tests to detect site-specific carcinogens has been shown previously using 22 chemicals in a study conducted by the Mammalian Mutagenicity Study group in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5167a34196efb86050c24657ebc58749
https://pubmed.ncbi.nlm.nih.gov/31326036
https://pubmed.ncbi.nlm.nih.gov/31326036
Autor:
Shoichi Kado, Katsuya Suzuki, Kayoko Komatsu, Kazumi Uchida, Ryota Tochinai, Tomo Suzuki, Yuriko Nagata, Chie Hata, Kimiyuki Kaneko, Minoru Ando, Masayoshi Kuwahara
Publikováno v:
Journal of Toxicologic Pathology
The microtubule inhibitor colchicine is cardiotoxic and is suggested to impair impulse formation and conduction. However, little is known about the electrocardiographic (ECG) changes induced by colchicine in experimental animals and the detailed path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b755c7320b3faebc07c11c971f21c0
http://europepmc.org/articles/PMC4217234
http://europepmc.org/articles/PMC4217234