Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shoib Sarwar Siddiqui"'
Autor:
Cijo George Vazhappilly, Shoib Sarwar Siddiqui, Ruby John Anto, Rajan Radhakrishnan, Naveen Kumar Devanga Ragupathi
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/83023b1cd65b403385e547fe9d8625b4
Autor:
Mohammed Saqif Ahmad, Maria Braoudaki, Hershna Patel, Irshad Ahmad, Shagufta, Shoib Sarwar Siddiqui
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Siglecs are well known immunotherapeutic targets in cancer. Current checkpoint inhibitors have exhibited limited efficacy, prompting a need for novel therapeutics for targets such as Siglec-15. Presently, small molecule inhibitors targeting Siglec-15
Externí odkaz:
https://doaj.org/article/fe8095863a714a81aed1e8991ed7ed9e
Autor:
Seba Alsawaf, Fatema Alnuaimi, Saba Afzal, Rinku Mariam Thomas, Ayshwarya Lakshmi Chelakkot, Wafaa S. Ramadan, Rawad Hodeify, Rachel Matar, Maxime Merheb, Shoib Sarwar Siddiqui, Cijo George Vazhappilly
Publikováno v:
Biology, Vol 11, Iss 12, p 1717 (2022)
The kidney is susceptible to reactive oxygen species-mediated cellular injury resulting in glomerulosclerosis, tubulointerstitial fibrosis, tubular cell apoptosis, and senescence, leading to renal failure, and is a significant cause of death worldwid
Externí odkaz:
https://doaj.org/article/38a7e9bb61c54c41865457e41d477965
Autor:
Rawad Hodeify, Shoib Sarwar Siddiqui, Rachel Matar, Cijo George Vazhappilly, Maxime Merheb, Hussain Al Zouabi, John Marton
Publikováno v:
Heliyon, Vol 7, Iss 1, Pp e06041- (2021)
Cisplatin (CDDP) is currently one of the most effective FDA-approved treatments for breast cancer. Previous studies have shown that CDDP-induced cell death in human breast cancer (MCF-7) cells is associated with disruption of calcium homeostasis. How
Externí odkaz:
https://doaj.org/article/0028820d3d34474e8872fdedc86bb0f5
Publikováno v:
Biomedicines, Vol 8, Iss 8, p 286 (2020)
The p53 protein plays a central role in mediating immune functioning and determines the fate of the cells. Its role as a tumor suppressor, and in transcriptional regulation and cytokine activity under stress conditions, is well defined. The wild type
Externí odkaz:
https://doaj.org/article/7ea0f8bde4b8406e98f344fb2fad06e8
Autor:
Shoib Sarwar Siddiqui, Rachel Matar, Maxime Merheb, Rawad Hodeify, Cijo George Vazhappilly, John Marton, Syed Azharuddin Shamsuddin, Hussain Al Zouabi
Publikováno v:
Cells, Vol 8, Iss 10, p 1125 (2019)
Siglecs (Sialic acid-binding immunoglobulin-type lectins) are a I-type lectin that typically binds sialic acid. Siglecs are predominantly expressed in immune cells and generate activating or inhibitory signals. They are also shown to be expressed on
Externí odkaz:
https://doaj.org/article/bbe64837c7e245c18c5b8e225e7286e7
Autor:
Maxime Merheb, Rachel Matar, Rawad Hodeify, Shoib Sarwar Siddiqui, Cijo George Vazhappilly, John Marton, Syed Azharuddin, Hussain AL Zouabi
Publikováno v:
Cells, Vol 8, Iss 5, p 433 (2019)
Mitochondria are unique organelles carrying their own genetic material, independent from that in the nucleus. This review will discuss the nature of mitochondrial DNA (mtDNA) and its levels in the cell, which are the key elements to consider when try
Externí odkaz:
https://doaj.org/article/54071c536e334e97b737d07c49589ebf
Autor:
Maria, Braoudaki, Mohammed Saqif, Ahmad, Denis, Mustafov, Sara, Seriah, Mohammad Naseem, Siddiqui, Shoib Sarwar, Siddiqui
Publikováno v:
Seminars in Cancer Biology. 86:436-449
Colorectal cancer (CRC) is considered the second cause of cancer death worldwide. The early diagnosis plays a key role in patient prognosis and subsequently overall survival. Similar to several types of cancer, colorectal cancer is also characterised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b56cbc7412aa2374c25bf0c7ba6d606
https://doi.org/10.1016/j.semcancer.2022.06.002
https://doi.org/10.1016/j.semcancer.2022.06.002
Autor:
Shoib Sarwar Siddiqui, Rawad Hodeify, Shimy Mathew, Seba Alsawaf, Anood Alghfeli, Rachel Matar, Maxime Merheb, John Marton, Hussain AbdulKarim Al Zouabi, Dhiviya Prabaa Muthuirulandi Sethuvel, Naveen Kumar Devanga Ragupathi, Cijo George Vazhappilly
Publikováno v:
Inflammopharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c95a58b1b6d3f2a9b6d378b11d00505
https://doi.org/10.1007/s10787-023-01247-4
https://doi.org/10.1007/s10787-023-01247-4
Autor:
Shoib Sarwar Siddiqui
Publikováno v:
Molecular aspects of medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a2f14acab457377ab40fed4e5f3a35
https://pubmed.ncbi.nlm.nih.gov/36243585
https://pubmed.ncbi.nlm.nih.gov/36243585