Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Shohreh Amini"'
Autor:
Nune Darbinian, Armine Darbinyan, Nana Merabova, Myrna Kassem, Gabriel Tatevosian, Shohreh Amini, Laura Goetzl, Michael E. Selzer
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionMitochondrial dysfunction is postulated to be a central event in fetal alcohol spectrum disorders (FASD). People with the most severe form of FASD, fetal alcohol syndrome (FAS) are estimated to live only 34 years (95% confidence interval,
Externí odkaz:
https://doaj.org/article/cd581b5194c84af399acf8a6b6b3268a
Autor:
Prasanta K. Dash, Rafal Kaminski, Ramona Bella, Hang Su, Saumi Mathews, Taha M. Ahooyi, Chen Chen, Pietro Mancuso, Rahsan Sariyer, Pasquale Ferrante, Martina Donadoni, Jake A. Robinson, Brady Sillman, Zhiyi Lin, James R. Hilaire, Mary Banoub, Monalisha Elango, Nagsen Gautam, R. Lee Mosley, Larisa Y. Poluektova, JoEllyn McMillan, Aditya N. Bade, Santhi Gorantla, Ilker K. Sariyer, Tricia H. Burdo, Won-Bin Young, Shohreh Amini, Jennifer Gordon, Jeffrey M. Jacobson, Benson Edagwa, Kamel Khalili, Howard E. Gendelman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-20 (2019)
Here, the authors show that sequential treatment with long-acting slow-effective release ART and AAV9- based delivery of CRISPR-Cas9 results in undetectable levels of virus and integrated DNA in a subset of humanized HIV-1 infected mice. This proof-o
Externí odkaz:
https://doaj.org/article/ad4b010214414d8c84777d8ae90f684b
Autor:
Ramona Bella, Rafal Kaminski, Pietro Mancuso, Won-Bin Young, Chen Chen, Rahsan Sariyer, Tracy Fischer, Shohreh Amini, Pasquale Ferrante, Jeffrey M. Jacobson, Fatah Kashanchi, Kamel Khalili
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 12, Iss , Pp 275-282 (2018)
We used NOD/SCID mice, also known as NRG, to assess the ability of lentivirus-mediated intravenous delivery of CRISPR in editing the HIV-1 genome from the circulating PBMC engrafts, some of which homed within several animal solid tissues. Lentivirus-
Externí odkaz:
https://doaj.org/article/c3b71237f904449d850998e4e755e66e
Autor:
Daniel Gonzalez, Julien Hiblot, Nune Darbinian, Jernelle C. Miller, Guillaume Gotthard, Shohreh Amini, Eric Chabriere, Mikael Elias
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 121-127 (2014)
Stable and soluble proteins are ideal candidates for functional and structural studies. Unfortunately, some proteins or enzymes can be difficult to isolate, being sometimes poorly expressed in heterologous systems, insoluble and/or unstable. Numerous
Externí odkaz:
https://doaj.org/article/1f39595541af4daabc6dce54893eef7f
Autor:
Shohreh Amini, Shahab Mohaghegh
Publikováno v:
Fluids, Vol 4, Iss 3, p 126 (2019)
Reservoir simulation models are the major tools for studying fluid flow behavior in hydrocarbon reservoirs. These models are constructed based on geological models, which are developed by integrating data from geology, geophysics, and petro-physics.
Externí odkaz:
https://doaj.org/article/a9289e9853fb44ed965dc5d09108eead
Autor:
Rafal Kaminski, Hassen S Wollebo, Prasun K Datta, Martyn K White, Shohreh Amini, Kamel Khalili
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98304 (2014)
Transcription from the HIV-1 promoter is controlled by a series of ubiquitous and inducible cellular proteins with the ability to enter the nucleus and interact with the promoter. A DNA sequence spanning nucleotides -120 to -80, which supports the as
Externí odkaz:
https://doaj.org/article/ec0c9eb3cd4d4314b775fbb844c2a5f9
Autor:
Jennifer Gordon, Ilker K Sariyer, Marisol De La Fuente-Granada, Brian J Augelli, Jessica Otte, S Ausim Azizi, Shohreh Amini, Kamel Khalili, Barbara Krynska
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65947 (2013)
JC virus (JCV), a common human polyomavirus, is the etiological agent of the demyelinating disease, progressive multifocal leukoencephalopathy (PML). In addition to its role in PML, studies have demonstrated the transforming ability of the JCV early
Externí odkaz:
https://doaj.org/article/0f9509b1975547709df9ea85b878f522
Autor:
Rakhee Sachdeva, Nune Darbinian, Kamel Khalili, Shohreh Amini, Daniel Gonzalez, Ahmed Djeghader, Eric Chabriére, Andrew Suh, Ken Scott, Malgorzata Simm
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e69623 (2013)
Independent research groups reported that DING protein homologues isolated from bacterial, plant and human cells demonstrate the anti-HIV-1 activity. This might indicate that diverse organisms utilize a DING-mediated broad-range protective innate imm
Externí odkaz:
https://doaj.org/article/e5564c10024e4c07bc8e945016224de9
Autor:
Carlos A Barrero, Prasun K Datta, Satarupa Sen, Satish Deshmane, Shohreh Amini, Kamel Khalili, Salim Merali
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68376 (2013)
Human immunodeficiency virus type 1 encoded viral protein Vpr is essential for infection of macrophages by HIV-1. Furthermore, these macrophages are resistant to cell death and are viral reservoir. However, the impact of Vpr on the macrophage proteom
Externí odkaz:
https://doaj.org/article/565ecf7396b94dd98a70805bd8449410
Autor:
Prasanta K. Dash, Chen Chen, Rafal Kaminski, Hang Su, Pietro Mancuso, Brady Sillman, Chen Zhang, Shuren Liao, Sruthi Sravanam, Hong Liu, Emiko Waight, Lili Guo, Saumi Mathews, Rahsan Sariyer, R. Lee Mosley, Larisa Y. Poluektova, Maurizio Caocci, Shohreh Amini, Santhi Gorantla, Tricia H. Burdo, Benson Edagwa, Howard E. Gendelman, Kamel Khalili
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Treatment of HIV-1 ADA -infected CD34+ NSG-humanized mice with long-acting ester prodrugs of cabotegravir, lamivudine, and abacavir in combination with native rilpivirine was followed by dual CRISPR-Cas9 C-C chemokine receptor type five (CCR5) and HI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0521cb8aacc7a64087afd83a552e4482
https://doi.org/10.1073/pnas.2217887120
https://doi.org/10.1073/pnas.2217887120