Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shohini Ghosh-Choudhary"'
Autor:
Shohini Ghosh-Choudhary, Neil Carleton, S. Mehdi Nouraie, Corrine R. Kliment, Richard A. Steinman
Publikováno v:
JCI Insight, Vol 7, Iss 6 (2022)
MD-PhD trainees constitute an important source of physician-scientists. Persistence on this challenging path is facilitated by success in garnering independent (R grant) support from the NIH. Published research tracks academic appointments and global
Externí odkaz:
https://doaj.org/article/bc7f739c93324026aeb9b50a6951001a
Autor:
Kristin M. French, Joshua T. Maxwell, Srishti Bhutani, Shohini Ghosh-Choudhary, Marcos J. Fierro, Todd D. Johnson, Karen L. Christman, W. Robert Taylor, Michael E. Davis
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Cardiac progenitor cells (CPCs) have rapidly advanced to clinical trials, yet little is known regarding their interaction with the microenvironment. Signaling cues present in the microenvironment change with development and disease. This work aims to
Externí odkaz:
https://doaj.org/article/6de0e541fe5a45b19336e150975bb8d6
Publikováno v:
Acad Med
Substantial gender inequities persist across academic medicine. These issues are not new: Recent evidence still points to a chilly climate for women in academic medicine, including those in physician-scientist training. The discussion for how to addr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4e374873d6854c4d1f2b177a24145b
https://europepmc.org/articles/PMC8770678/
https://europepmc.org/articles/PMC8770678/
Publikováno v:
FASEB J
Mitochondria are intimately connected to cell fate and function. Here, we review how these intracellular organelles participate in the induction and maintenance of the senescent state. In particular, we discuss how alterations in mitochondrial metabo
Autor:
Laxminath Tumburu, Mehdi Pirooznia, Arun S. Shet, Luis E.F. Almeida, James S. Nichols, Jun Zhu, Eric Lindberg, Maliha Maryam Ahmad, Christopher K. E. Bleck, Ilker Tunc, Ishwarya Sivakumar, Christian A. Combs, Emilia Alina Barbu, Fayaz Seifuddin, Lauren H. W. Wilkins, Swee Lay Thein, Shohini Ghosh-Choudhary, Shutong Yang, Simon Yang, Pradeep K. Dagur, Zenaide M.N. Quezado, Jay H. Chung
Publikováno v:
Blood
The pathophysiology of sickle cell disease (SCD) is driven by chronic inflammation fueled by damage associated molecular patterns (DAMPs). We show that elevated cell-free DNA (cfDNA) in patients with SCD is not just a prognostic biomarker, it also co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd088c5875ba43424f5c0c86979f0f0
https://europepmc.org/articles/PMC8176765/
https://europepmc.org/articles/PMC8176765/
Publikováno v:
Advances in experimental medicine and biology. 1303
Reductionist approaches have served as the cornerstone for traditional mechanistic endeavors in biomedical research. However, for pulmonary hypertension (PH), a relatively rare but deadly vascular disease of the lungs, the use of traditional reductio
Autor:
Zijian Zhang, James C. Gumbart, Alexandra Atalis, Emily J. Devereaux, Randall Toy, Pallab Pradhan, Shohini Ghosh-Choudhary, Simran Dhal, Casey E. Vantucci, Nick J. Willett, Jinhwan Kim, Krishnendu Roy, Katie M. Kuo, Jiaying Liu, Jianguo Wen, Da Huo, Kelsey P. Kubelick, Stanislav Emelianov, Zhiheng Lyu, Younan Xia
Publikováno v:
Nano Lett
Monoclonal antibodies (mAb) have had a transformative impact on treating cancers and immune-disorders. However, their use is limited by high development time and monetary cost, manufacturing complexities, suboptimal pharmacokinetics, and availability
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030630454
Reductionist approaches have served as the cornerstone for traditional mechanistic endeavors in biomedical research. However, for pulmonary hypertension (PH), a relatively rare but deadly vascular disease of the lungs, the use of traditional reductio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a80d158c16d7ea0409aad31a11ec7f1
https://doi.org/10.1007/978-3-030-63046-1_4
https://doi.org/10.1007/978-3-030-63046-1_4
Autor:
Susmita Sahoo, Joshua T. Maxwell, Michael Davis, Yash Mehta, Alex George, Shohini Ghosh-Choudhary, Srishti Bhutani, Yaxuan Liang, Milton E. Brown, Udit Agarwal, Manu O. Platt
Publikováno v:
Circulation Research. 120:701-712
Rationale : Studies have demonstrated that exosomes can repair cardiac tissue post–myocardial infarction and recapitulate the benefits of cellular therapy. Objective : We evaluated the role of donor age and hypoxia of human pediatric cardiac progen
Publikováno v:
Trends Cell Biol
Increasing evidence has implicated metabolic pathways as key regulators of cell fate and function. While the metabolism of glucose, amino acids and fatty acids are essential to maintain overall energy homeostasis, the choice of a given metabolic path