Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shogo Narimatsu"'
Autor:
Aiko Hasegawa, Shoji Saito, Shogo Narimatsu, Shigeru Nakano, Mika Nagai, Hideki Ohnota, Yoichi Inada, Hirokazu Morokawa, Ikumi Nakashima, Daisuke Morita, Yuichiro Ide, Kazuyuki Matsuda, Haruko Tashiro, Shigeki Yagyu, Miyuki Tanaka, Yozo Nakazawa
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 5, Pp n/a-n/a (2021)
Abstract Objectives As the prognosis of relapsed/refractory (R/R) acute myeloid leukaemia (AML) remains poor, novel treatment strategies are urgently needed. Clinical trials have shown that chimeric antigen receptor (CAR)‐T cells for AML are more c
Externí odkaz:
https://doaj.org/article/1425b53972624649b7548613523d6ce8
Autor:
Hiroshi Inakura, Yohei Mukai, Shogo Narimatsu, Yasuo Yoshioka, Aya Tanabe, Shinsaku Nakagawa, Naoki Okada, Xinglei Yao, Shin-ichi Tsunoda, Tomohiro Morishige, Yasuo Tsutsumi, Youko Monobe, Takayoshi Imazawa
Publikováno v:
Archives of Toxicology. 86:1297-1307
It has gradually become evident that nanomaterials, which are widely used in cosmetics, foods, and medicinal products, could induce substantial inflammation. However, the roles played by the physical characteristics of nanomaterials in inflammatory r
Autor:
Shinsaku Nakagawa, Naoki Okada, Tomohiro Morishige, Yohei Mukai, Shogo Narimatsu, Yasuo Yoshioka, Shin-ichi Tsunoda, Xinglei Yao, Yasuo Tsutsumi, Michael I Nishimura
Publikováno v:
Biochemical and Biophysical Research Communications. 415:558-562
T-cell receptors (TCR) recognize complexes between human leukocyte antigens (HLA) and peptides derived from intracellular proteins. Their therapeutic use for antigen targeting, however, has been hindered by the very low binding affinity of TCRs, typi
Autor:
Yohei Mukai, Hikaru Watanabe, Tomohiro Morishige, Shogo Narimatsu, Yasuo Yoshioka, Xinglei Yao, Shin-ichi Tsunoda, Shinsaku Nakagawa, Aya Tanabe, Takashi Masano, Yasuo Tsutsumi, Naoki Okada
Publikováno v:
Cytokine. 56:489-493
The cytokine lymphotoxin-α (LTα) is a promising anticancer agent; however, its instability currently limits its therapeutic potential. Modification of proteins with polyethylene glycol (PEGylation) can improve their in vivo stability, but PEGylatio
Autor:
Shogo Yamamoto, Miho Miura, Hiroyuki Katayama, Takashi Furukawa, Shogo Narimatsu, Yoshihiro Suzuki, Akira Iwakiri
Publikováno v:
Journal of Bioscience and Bioengineering. 112:369-372
The monitoring of NVs in municipal wastewater by both real-time RT-LAMP and real-time RT-PCR, and the comparison of these two methods with respect to NV detection were carried out. The change in NVs detected by real-time RT-LAMP agreed well with that
Autor:
Tomohiro Morishige, Yusuke Eto, Xinglei Yao, Hiroyuki Mizuguchi, Yohei Mukai, Naoki Okada, Shogo Narimatsu, Shinsaku Nakagawa, Yasuo Yoshioka
Publikováno v:
Biological and Pharmaceutical Bulletin. 33:1073-1076
Cancer gene therapy with adenovirus vectors (Adv) is limited to local administration because systemic administration of Adv produces a weak therapeutic effect and severe side effects. Previously, we generated a dual cancer-specific Adv system by usin
Autor:
Yasuo Yoshioka, Yohei Mukai, Shogo Narimatsu, Tomohiro Morishige, Shinji Ikemizu, Shin-ichi Tsunoda, Naoki Okada, Shinsaku Nakagawa, Yasuo Tsutsumi
Publikováno v:
Cytokine. 61(2)
The cytokine lymphotoxin-α (LTα) is a promising candidate for use in cancer therapy. However, the instability of LTαin vivo and the insufficient levels of tumor necrosis factor receptor 1 (TNFR1)-mediated bioactivity of LTα limit its therapeutic
Autor:
Yasuaki Kawai, Hiroyuki Mizuguchi, Naoki Okada, Yohei Mukai, Jian-Qing Gao, Yasuo Yoshioka, Shinsaku Nakagawa, Shogo Narimatsu, Yusuke Eto, Tomohiro Morishige, Xinglei Yao
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 19(9)
Previously, we generated a cancer-specific gene therapy system using adenovirus vectors (Adv) conjugated to polyethylene glycol (Adv-PEG). Here, we developed a novel Adv that targets both tumor tissues and tumor vasculatures after systemic administra
Autor:
Xinglei Yao, Hiroshi Kiwada, Shinsaku Nakagawa, Yohei Mukai, Shogo Narimatsu, Tomohiro Morishige, Yasuo Yoshioka, Hiroyuki Mizuguchi, Yusuke Eto, Naoki Okada, Tatsuhiro Ishida
Publikováno v:
Biologicalpharmaceutical bulletin. 33(9)
Application of adenovirus vectors (Adv) in metastatic cancer treatment is limited. We previously demonstrated that covalent conjugation of polyethleneglycol (PEG) to Adv enhances therapeutic effects and decreases toxic side-effects after systemic adm
Autor:
Xinglei Yao, Takayoshi Imazawa, Shinsaku Nakagawa, Hiroshi Inakura, Yasuo Yoshioka, Yasuo Tsutsumi, Yohei Mukai, Shin-ichi Tsunoda, Shogo Narimatsu, Aya Tanabe, Naoki Okada, Youko Monobe, Tomohiro Morishige
Publikováno v:
Biomaterials. 31(26)
Although amorphous silica particles (SPs) are widely used in cosmetics, foods and medicinal products, it has gradually become evident that SPs can induce substantial inflammation accompanied by interleukin-1beta (IL-1beta) production. Here, to develo