Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shogo Kuwagata"'
Autor:
Yoshimi Imamura-Uehara, Mako Yasuda-Yamahara, Shogo Kuwagata, Kosuke Yamahara, Mamoru Yoshibayashi, Yuki Tanaka-Sasaki, Akio Shimizu, Hisakazu Ogita, Masami Chin-Kanasaki, Shinji Kume
Publikováno v:
Biochemistry and Biophysics Reports, Vol 37, Iss , Pp 101607- (2024)
Renal artery stenosis-induced chronic renal ischemia is an important cause of renal dysfunction, especially in older adults, and its incidence is currently increasing. To elucidate the mechanisms underlying chronic renal hypoperfusion-induced kidney
Externí odkaz:
https://doaj.org/article/c46db925d33343ed9e64a58237eff28d
Autor:
Issei Tomita, Hiroaki Tsuruta, Mako Yasuda‐Yamahara, Kosuke Yamahara, Shogo Kuwagata, Yuki Tanaka‐Sasaki, Masami Chin‐Kanasaki, Yukihiro Fujita, Eiichiro Nishi, Hideki Katagiri, Hiroshi Maegawa, Shinji Kume
Publikováno v:
Aging Cell.
Accumulating evidence suggests health benefits of ketone bodies, and especially for longevity. However, the precise role of endogenous ketogenesis in mammalian life span, and the safety and efficacy of the long-term exogenous supplementation of keton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55500c0336a400b1c5c41dddf0242bf9
https://doi.org/10.1111/acel.13833
https://doi.org/10.1111/acel.13833
Autor:
Yoshihiko Fujino, Mako Yasuda-Yamahara, Yuki Tanaka-Sasaki, Shogo Kuwagata, Kosuke Yamahara, Atsuko Tagawa, Masami Chin-Kanasaki, Motoko Yanagita, Hiroshi Maegawa, Shinji Kume
Publikováno v:
Biochemical and biophysical research communications. 620:15-20
Lipoprotein lipase (LPL) is an enzyme that catalyzes the hydrolysis of circulating triglyceride and the transport of fatty acids into cells. Its activity is positively regulated by insulin, and insulin resistance is associated with low LPL activity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4434302144e79201d69802a8c59bdb97
http://hdl.handle.net/10422/00013367
http://hdl.handle.net/10422/00013367
Autor:
Shinji Kume, Mako Yasuda-Yamahara, Yoshimi Imamura-Uehara, Shogo Kuwagata, Kosuke Yamahara, Naoko Takeda, Masami Chin-Kanasaki, Koichi Kato, Seiko Ohno, Yoshihisa Nakagawa, Hiroshi Maegawa
Publikováno v:
Internal medicine (Tokyo, Japan). 61(20)
Fabry disease is an inherited lysosomal disorder caused by mutations in the alpha-galactosidase A gene. We herein report a Fabry disease patient with enzyme replacement therapy (ERT)-resistant proteinuria who showed improvement in the estimated glome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f98ddd37e2231ac84e8d42d6de166b
https://pubmed.ncbi.nlm.nih.gov/35283375
https://pubmed.ncbi.nlm.nih.gov/35283375
Autor:
Makoto Tagaya, Shinji Kume, Mako Yasuda-Yamahara, Shogo Kuwagata, Kosuke Yamahara, Naoko Takeda, Yuki Tanaka, Masami Chin-Kanasaki, Yuki Nakae, Hideki Yokoi, Masashi Mukoyama, Naotada Ishihara, Masatoshi Nomura, Shin-ichi Araki, Hiroshi Maegawa
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1868(5)
Aims:Identifying the mechanisms that underlie progression from endothelial damage to podocyte damage, which leads to massive proteinuria, is an urgent issue that must be clarified to improve renal outcome in diabetic kidney disease (DKD). We aimed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c3b596cd885365bdbd3cf6fd93231a
http://hdl.handle.net/10422/00013229
http://hdl.handle.net/10422/00013229
Autor:
Shin-ichi Araki, Makoto Tagaya, Shogo Kuwagata, Masami Kanasaki, Shoji Omachi, Yoshimi Imamura, Natsuko Tomita, Hiroshi Maegawa, Hiroaki Turuta, Eri Oi, Kazunobu Sawai, Shinji Kume, Yuuji Sasaki
Publikováno v:
Nihon Toseki Igakkai Zasshi. 51:463-467
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d92e66d574044ae77765790885e1ec8b
https://doi.org/10.4009/jsdt.51.463
https://doi.org/10.4009/jsdt.51.463
Autor:
Hisazumi Araki, Daisuke Koya, Shogo Kuwagata, Takeshi Sugaya, Masami Chin-Kanasaki, Shinji Kume, Masakazu Haneda, Jun Nakazawa, Takashi Uzu, Shin-ichi Araki, Hiroshi Maegawa
Publikováno v:
Kidney International. 90:1211-1225
Hypoxia causes proximal tubular cell damage in diabetes, even though proximal tubular cells have an adaptive system to combat hypoxia involving induction of hypoxia factor-1 (HIF-1) and inhibition of mechanistic target of rapamycin complex 1 (mTORC1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92816839716bf3dfc11651e8971fdca9
https://doi.org/10.1016/j.kint.2016.06.036
https://doi.org/10.1016/j.kint.2016.06.036
Autor:
Shogo Kuwagata, Yoshinori Tsujimura, Yoshikata Morita, Hiromi Mizutani, Mitsuhiro Suehiro, Motohide Isono, Noriko Kato
Publikováno v:
Internal Medicine. 51:1613-1618
Interstitial lung disease (ILD) frequently accompanies polymyositis (PM) and dermatomyositis (DM) and is a major cause of mortality. The rapid diagnosis of ILD is paramount. However, the early changes of presymptomatic ILD are difficult to detect. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea77bd576992bb3da7b39f0cfc51cc03
https://doi.org/10.2169/internalmedicine.51.6813
https://doi.org/10.2169/internalmedicine.51.6813
Publikováno v:
Leukemia Research. 30:1235-1239
The progenitor cells of myelodysplastic syndrome (MDS) are thought to undergo a multistep process during their transformation into overt acute leukemia. In this study, the role of mutation of the KIT gene in the extracellular membrane, juxtamembrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ede4b440e78cff4d0ef193089f95112
https://doi.org/10.1016/j.leukres.2006.02.008
https://doi.org/10.1016/j.leukres.2006.02.008
Autor:
Kosuke Yamahara, Atsunori Kashiwagi, Shinji Kume, Keiji Isshiki, Hisazumi Araki, Yoshikata Morita, Takashi Uzu, Shogo Kuwagata, Shin-ichi Araki, Hiroshi Maegawa, Mariko Soumura
Publikováno v:
Clinical and Experimental Nephrology
Background Because oral nonsteroidal anti-inflammatory drugs (NSAIDs) have adverse effects on kidney function, patients with kidney diseases are administered these drugs as transdermal patches. Little is known about the effects of NSAID patches on re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75fea57a5defe588888e5c2d900f052d
https://pubmed.ncbi.nlm.nih.gov/23921417
https://pubmed.ncbi.nlm.nih.gov/23921417